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Rtn4rl1 reticulon 4 receptor-like 1 [ Mus musculus (house mouse) ]

Gene ID: 237847, updated on 3-Apr-2018

Summary

Official Symbol
Rtn4rl1provided by MGI
Official Full Name
reticulon 4 receptor-like 1provided by MGI
Primary source
MGI:MGI:2661375
See related
Ensembl:ENSMUSG00000045287 Vega:OTTMUSG00000006197
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Ngr3; Ngrh2; Ngrl2
Expression
Broad expression in adrenal adult (RPKM 25.5), bladder adult (RPKM 10.8) and 22 other tissues See more
Orthologs

Genomic context

See Rtn4rl1 in Genome Data Viewer
Location:
11; 11 B5
Exon count:
3
Annotation release Status Assembly Chr Location
106 current GRCm38.p4 (GCF_000001635.24) 11 NC_000077.6 (75193993..75267769)
Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 11 NC_000077.5 (75007495..75081264)

Chromosome 11 - NC_000077.6Genomic Context describing neighboring genes Neighboring gene microRNA 132 Neighboring gene candidate tumor suppressor in ovarian cancer 2 Neighboring gene diphthamide biosynthesis 1 Neighboring gene predicted gene, 35169 Neighboring gene predicted gene, 35117 Neighboring gene replication protein A1 Neighboring gene SET and MYND domain containing 4

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)

Pathways from BioSystems

General gene information

Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
chondroitin sulfate binding IDA
Inferred from Direct Assay
more info
PubMed 
heparin binding IMP
Inferred from Mutant Phenotype
more info
PubMed 
signaling receptor activity ISO
Inferred from Sequence Orthology
more info
 
Process Evidence Code Pubs
corpus callosum development IMP
Inferred from Mutant Phenotype
more info
PubMed 
negative regulation of axon regeneration IMP
Inferred from Mutant Phenotype
more info
PubMed 
negative regulation of neuron projection development IMP
Inferred from Mutant Phenotype
more info
PubMed 
Component Evidence Code Pubs
anchored component of membrane IEA
Inferred from Electronic Annotation
more info
 
anchored component of plasma membrane ISO
Inferred from Sequence Orthology
more info
 
cell projection IEA
Inferred from Electronic Annotation
more info
 
cell surface ISO
Inferred from Sequence Orthology
more info
 
external side of plasma membrane ISO
Inferred from Sequence Orthology
more info
 
integral component of membrane IEA
Inferred from Electronic Annotation
more info
 
membrane IEA
Inferred from Electronic Annotation
more info
 
membrane raft ISO
Inferred from Sequence Orthology
more info
 
plasma membrane IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
reticulon-4 receptor-like 1
Names
nogo receptor-like 2
nogo-66 receptor homolog 2
nogo-66 receptor-related protein 3
rtn4rl1

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_177708.5NP_808376.1  reticulon-4 receptor-like 1 precursor

    See identical proteins and their annotated locations for NP_808376.1

    Status: PROVISIONAL

    Source sequence(s)
    AK140456
    Consensus CDS
    CCDS25043.1
    UniProtKB/Swiss-Prot
    Q8K0S5
    Related
    ENSMUSP00000099572.3, OTTMUSP00000006489, ENSMUST00000102514.3, OTTMUST00000013970
    Conserved Domains (4) summary
    cd00116
    Location:102255
    LRR_RI; Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond ...
    sd00033
    Location:78101
    LRR_RI; leucine-rich repeat [structural motif]
    pfam12799
    Location:150188
    LRR_4; Leucine Rich repeats (2 copies)
    pfam13855
    Location:174233
    LRR_8; Leucine rich repeat

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 106

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm38.p4 C57BL/6J

Genomic

  1. NC_000077.6 Reference GRCm38.p4 C57BL/6J

    Range
    75193993..75267769
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006533225.2XP_006533288.1  reticulon-4 receptor-like 1 isoform X1

    Conserved Domains (4) summary
    cd00116
    Location:155308
    LRR_RI; Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond ...
    sd00033
    Location:131154
    LRR_RI; leucine-rich repeat [structural motif]
    pfam12799
    Location:203241
    LRR_4; Leucine Rich repeats (2 copies)
    pfam13855
    Location:227286
    LRR_8; Leucine rich repeat
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