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TOP3BP1 DNA topoisomerase III beta pseudogene 1 [ Homo sapiens (human) ]

Gene ID: 23751, updated on 2-Sep-2022

Summary

Official Symbol
TOP3BP1provided by HGNC
Official Full Name
DNA topoisomerase III beta pseudogene 1provided by HGNC
Primary source
HGNC:HGNC:11994
See related
AllianceGenome:HGNC:11994
Gene type
pseudo
RefSeq status
REVIEWED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
TOP3B2
Summary
This gene was predicted by automated computational analysis. It encodes a protein with similarity to human topoisomerase (DNA) III beta, which is thought to relax supercoiled DNA upon replication, transcription, and cell division. This gene lies in the immunoglobulin lambda gene cluster on chromosome 22q11.21. [provided by RefSeq, Jul 2008]
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Genomic context

See TOP3BP1 in Genome Data Viewer
Location:
22q11.22
Annotation release Status Assembly Chr Location
110 current GRCh38.p14 (GCF_000001405.40) 22 NC_000022.11 (22223186..22223665, complement)
110 current T2T-CHM13v2.0 (GCF_009914755.1) 22 NC_060946.1 (22636740..22637219, complement)
105.20220307 previous assembly GRCh37.p13 (GCF_000001405.25) 22 NC_000022.10 (22577579..22578058, complement)

Chromosome 22 - NC_000022.11Genomic Context describing neighboring genes Neighboring gene immunoglobulin lambda locus Neighboring gene URI1, prefoldin-like chaperone pseudogene Neighboring gene immunoglobulin lambda variable 10-54 Neighboring gene immunoglobulin lambda variable (IV)-53 (pseudogene) Neighboring gene V-set pre-B cell surrogate light chain 1

Genomic regions, transcripts, and products

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

Genomic

  1. NG_000002.1 

    Range
    201568..202047 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 110 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000022.11 Reference GRCh38.p14 Primary Assembly

    Range
    22223186..22223665 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060946.1 Alternate T2T-CHM13v2.0

    Range
    22636740..22637219 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)