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Cdk17 cyclin-dependent kinase 17 [ Mus musculus (house mouse) ]

Gene ID: 237459, updated on 12-Aug-2019

Summary

Official Symbol
Cdk17provided by MGI
Official Full Name
cyclin-dependent kinase 17provided by MGI
Primary source
MGI:MGI:97517
See related
Ensembl:ENSMUSG00000020015
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Pctk2; 6430598J10Rik
Expression
Broad expression in frontal lobe adult (RPKM 15.4), cortex adult (RPKM 13.0) and 27 other tissues See more
Orthologs

Genomic context

See Cdk17 in Genome Data Viewer
Location:
10; 10 C2
Exon count:
23
Annotation release Status Assembly Chr Location
108 current GRCm38.p6 (GCF_000001635.26) 10 NC_000076.6 (93160876..93251094)
Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 10 NC_000076.5 (92623621..92704087)

Chromosome 10 - NC_000076.6Genomic Context describing neighboring genes Neighboring gene predicted gene, 40740 Neighboring gene predicted gene, 40741 Neighboring gene microRNA 1931 Neighboring gene ELK3, member of ETS oncogene family Neighboring gene predicted gene, 32551 Neighboring gene predicted gene, 32688

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Gene trapped (1) 
  • Endonuclease-mediated (1) 

Pathways from BioSystems

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Clone Names

  • MGC25109

Gene Ontology Provided by MGI

Function Evidence Code Pubs
ATP binding IEA
Inferred from Electronic Annotation
more info
 
cyclin-dependent protein serine/threonine kinase activity IEA
Inferred from Electronic Annotation
more info
 
kinase activity IEA
Inferred from Electronic Annotation
more info
 
nucleotide binding IEA
Inferred from Electronic Annotation
more info
 
protein kinase activity IEA
Inferred from Electronic Annotation
more info
 
protein serine/threonine kinase activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
transferase activity IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
phosphorylation IEA
Inferred from Electronic Annotation
more info
 
protein phosphorylation IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Component Evidence Code Pubs
cytoplasm IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
nucleus IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 

General protein information

Preferred Names
cyclin-dependent kinase 17
Names
PCTAIRE-motif protein kinase 2
Pctaire2
cell division protein kinase 17
serine/threonine-protein kinase PCTAIRE-2
NP_666351.2
XP_006513689.1
XP_006513690.1
XP_011241749.1
XP_030100944.1
XP_030100945.1
XP_030100946.1

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_146239.2NP_666351.2  cyclin-dependent kinase 17

    See identical proteins and their annotated locations for NP_666351.2

    Status: VALIDATED

    Source sequence(s)
    BB085519, BC064815, BQ442862, BU841444, BY130550, CD350146, CJ117086, CX242491, DV646930
    Consensus CDS
    CCDS48670.1
    UniProtKB/Swiss-Prot
    Q8K0D0
    Related
    ENSMUSP00000070355.7, ENSMUST00000069965.8
    Conserved Domains (2) summary
    cd07872
    Location:185493
    STKc_PCTAIRE2; Catalytic domain of the Serine/Threonine Kinase, PCTAIRE-2 kinase
    PLN00009
    Location:189477
    PLN00009; cyclin-dependent kinase A; Provisional

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 108 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm38.p6 C57BL/6J

Genomic

  1. NC_000076.6 Reference GRCm38.p6 C57BL/6J

    Range
    93160876..93251094
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_030245085.1XP_030100945.1  cyclin-dependent kinase 17 isoform X4

  2. XM_030245086.1XP_030100946.1  cyclin-dependent kinase 17 isoform X5

  3. XM_011243447.3XP_011241749.1  cyclin-dependent kinase 17 isoform X3

    See identical proteins and their annotated locations for XP_011241749.1

    UniProtKB/Swiss-Prot
    Q8K0D0
    Conserved Domains (2) summary
    cd07872
    Location:185493
    STKc_PCTAIRE2; Catalytic domain of the Serine/Threonine Kinase, PCTAIRE-2 kinase
    PLN00009
    Location:189477
    PLN00009; cyclin-dependent kinase A; Provisional
  4. XM_006513627.3XP_006513690.1  cyclin-dependent kinase 17 isoform X3

    See identical proteins and their annotated locations for XP_006513690.1

    UniProtKB/Swiss-Prot
    Q8K0D0
    Conserved Domains (2) summary
    cd07872
    Location:185493
    STKc_PCTAIRE2; Catalytic domain of the Serine/Threonine Kinase, PCTAIRE-2 kinase
    PLN00009
    Location:189477
    PLN00009; cyclin-dependent kinase A; Provisional
  5. XM_030245084.1XP_030100944.1  cyclin-dependent kinase 17 isoform X2

    Related
    ENSMUSP00000150873.1, ENSMUST00000215286.1
  6. XM_006513626.3XP_006513689.1  cyclin-dependent kinase 17 isoform X1

    Conserved Domains (1) summary
    cd07872
    Location:201509
    STKc_PCTAIRE2; Catalytic domain of the Serine/Threonine Kinase, PCTAIRE-2 kinase

RNA

  1. XR_003948686.1 RNA Sequence

  2. XR_003948687.1 RNA Sequence

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