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Il22ra2 interleukin 22 receptor, alpha 2 [ Mus musculus (house mouse) ]

Gene ID: 237310, updated on 27-Feb-2024

Summary

Official Symbol
Il22ra2provided by MGI
Official Full Name
interleukin 22 receptor, alpha 2provided by MGI
Primary source
MGI:MGI:2665114
See related
Ensembl:ENSMUSG00000039760 AllianceGenome:MGI:2665114
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
CRF2X; CRF2-10; CRF2-s1; Il-22bp
Summary
Predicted to enable interleukin-22 binding activity and interleukin-22 receptor activity. Acts upstream of or within negative regulation of inflammatory response and regulation of tyrosine phosphorylation of STAT protein. Located in cytosol. Orthologous to human IL22RA2 (interleukin 22 receptor subunit alpha 2). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Low expression observed in reference dataset See more
Orthologs
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Genomic context

See Il22ra2 in Genome Data Viewer
Location:
10 A3; 10 8.52 cM
Exon count:
5
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 10 NC_000076.7 (19497776..19510429)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 10 NC_000076.6 (19622028..19634681)

Chromosome 10 - NC_000076.7Genomic Context describing neighboring genes Neighboring gene STARR-seq mESC enhancer starr_25937 Neighboring gene predicted gene, 33104 Neighboring gene STARR-positive B cell enhancer mm9_chr10:19238623-19238923 Neighboring gene STARR-seq mESC enhancer starr_25938 Neighboring gene CapStarr-seq enhancer MGSCv37_chr10:19303894-19304196 Neighboring gene STARR-positive B cell enhancer ABC_E2317 Neighboring gene interferon gamma receptor 1 Neighboring gene STARR-seq mESC enhancer starr_25939 Neighboring gene predicted gene, 33332 Neighboring gene CapStarr-seq enhancer MGSCv37_chr10:19411574-19411868 Neighboring gene interleukin 20 receptor, alpha Neighboring gene predicted gene, 25256

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Targeted (7)  1 citation
  • Endonuclease-mediated (3) 

General protein information

Preferred Names
interleukin-22 receptor subunit alpha-2
Names
IL-22 receptor subunit alpha-2
IL-22R-alpha-2
IL-22RA2
IL22BP
cytokine receptor family II soluble 1
cytokine receptor family type 2, soluble 1
interleukin-22-binding protein
zcytoR16

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_178258.5NP_839989.2  interleukin-22 receptor subunit alpha-2 precursor

    See identical proteins and their annotated locations for NP_839989.2

    Status: PROVISIONAL

    Source sequence(s)
    AK138913
    Consensus CDS
    CCDS23717.1
    UniProtKB/Swiss-Prot
    Q3UU14, Q7TNI5, Q80XF5
    UniProtKB/TrEMBL
    Q08AV1, Q3UTW4, Q3V3G3
    Related
    ENSMUSP00000042642.8, ENSMUST00000036564.8
    Conserved Domains (2) summary
    pfam01108
    Location:30113
    Tissue_fac; Tissue factor
    pfam09294
    Location:125230
    Interfer-bind; Interferon-alpha/beta receptor, fibronectin type III

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000076.7 Reference GRCm39 C57BL/6J

    Range
    19497776..19510429
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)