Smok2b sperm motility kinase 2B [Mus musculus (house mouse)] - Gene

Summary

Official Symbol: Smok2bprovided by MGI
Official Full Name: sperm motility kinase 2Bprovided by MGI
Primary source: MGI:MGI:3037705
See related: Ensembl:ENSMUSG00000073457 AllianceGenome:MGI:3037705
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Mus musculus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as: Gm1847; Smok+129
Summary: Enables protein kinase activity. Acts upstream of or within protein phosphorylation. [provided by Alliance of Genome Resources, Apr 2022]
Expression: Restricted expression toward testis adult (RPKM 2.8) See more
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Genomic context

Location:: 17; 17 A1

Exon count:: 3

Annotation release	Status	Assembly	Chr	Location
109	current	GRCm39 (GCF_000001635.27)	17	NC_000083.7 (13449150..13456076)
108.20200622	previous assembly	GRCm38.p6 (GCF_000001635.26)	17	NC_000083.6 (13230263..13237189)

Chromosome 17 - NC_000083.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: Mouse ENCODE transcriptome data
Description: RNA profiling data sets generated by the Mouse ENCODE project.
BioProject: PRJNA66167
Publication: PMID 25409824
Analysis date: n/a

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Gene Ontology Provided by MGI

Function	Evidence Code	Pubs
enables ATP binding	IEA Inferred from Electronic Annotation more info
enables kinase activity	IEA Inferred from Electronic Annotation more info
enables nucleotide binding	IEA Inferred from Electronic Annotation more info
enables protein kinase activity	IDA Inferred from Direct Assay more info	PubMed
enables protein serine/threonine kinase activity	IBA Inferred from Biological aspect of Ancestor more info	PubMed
enables transferase activity	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
involved_in cellular response to glucose starvation	IBA Inferred from Biological aspect of Ancestor more info	PubMed
involved_in intracellular signal transduction	IBA Inferred from Biological aspect of Ancestor more info	PubMed
involved_in negative regulation of TOR signaling	IBA Inferred from Biological aspect of Ancestor more info	PubMed
acts_upstream_of_or_within phosphorylation	IEA Inferred from Electronic Annotation more info
involved_in protein phosphorylation	IBA Inferred from Biological aspect of Ancestor more info	PubMed
acts_upstream_of_or_within protein phosphorylation	IDA Inferred from Direct Assay more info	PubMed

Component	Evidence Code	Pubs
part_of nucleotide-activated protein kinase complex	IBA Inferred from Biological aspect of Ancestor more info	PubMed

General protein information

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Preferred Names: sperm motility kinase 2B

NP_001161385.1

EC 2.7.11.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001167913.2 → NP_001161385.1 sperm motility kinase 2B

See identical proteins and their annotated locations for NP_001161385.1

Status: VALIDATED

Source sequence(s)

AC166099, AC166360

Consensus CDS

CCDS49952.1

UniProtKB/Swiss-Prot

Q9QYZ3

Related

ENSMUSP00000124967.2, ENSMUST00000162940.3

Conserved Domains (3) summary

smart00220
Location:8 → 256

S_TKc; Serine/Threonine protein kinases, catalytic domain

cd14337
Location:275 → 314

UBA_MARK_Par1; UBA domain found in microtubule-associated protein (MAP)/microtubule affinity-regulating kinase (MARK)/ partitioning-defective 1 (Par-1) and similar proteins

cd14003
Location:7 → 255

STKc_AMPK-like; Catalytic domain of AMP-activated protein kinase-like Serine/Threonine Kinases