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SNHG1 small nucleolar RNA host gene 1 [ Homo sapiens (human) ]

Gene ID: 23642, updated on 23-Nov-2021

Summary

Official Symbol
SNHG1provided by HGNC
Official Full Name
small nucleolar RNA host gene 1provided by HGNC
Primary source
HGNC:HGNC:32688
See related
Ensembl:ENSG00000255717 MIM:603222
Gene type
ncRNA
RefSeq status
REVIEWED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
UHG; U22HG; lncRNA16; LINC00057; NCRNA00057
Summary
This locus represents a small nucleolar RNA host gene that produces multiple alternatively spliced long non-coding RNAs. This gene is upregulated in cancers and is thought to act as promoter of cell proliferation. This transcript negatively regulates tumor suppressor genes such as tumor protein p53. Expression of this locus may be a marker of tumor progression. [provided by RefSeq, Dec 2017]
Expression
Broad expression in bone marrow (RPKM 85.9), ovary (RPKM 53.7) and 23 other tissues See more
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Genomic context

See SNHG1 in Genome Data Viewer
Location:
11q12.3
Exon count:
11
Annotation release Status Assembly Chr Location
109.20211119 current GRCh38.p13 (GCF_000001405.39) 11 NC_000011.10 (62851978..62855885, complement)
105.20201022 previous assembly GRCh37.p13 (GCF_000001405.25) 11 NC_000011.9 (62619450..62623357, complement)

Chromosome 11 - NC_000011.10Genomic Context describing neighboring genes Neighboring gene STX5 divergent transcript Neighboring gene testis expressed 54 Neighboring gene WD repeat domain 74 Neighboring gene RNA, U2 small nuclear 2, pseudogene Neighboring gene small nucleolar RNA, C/D box 22 Neighboring gene small nucleolar RNA, C/D box 31 Neighboring gene small nucleolar RNA, C/D box 30 Neighboring gene small nucleolar RNA, C/D box 29 Neighboring gene small nucleolar RNA, C/D box 28 Neighboring gene small nucleolar RNA, C/D box 27 Neighboring gene small nucleolar RNA, C/D box 26 Neighboring gene small nucleolar RNA, C/D box 25 Neighboring gene solute carrier family 3 member 2 Neighboring gene uncharacterized LOC105369333 Neighboring gene cholinergic receptor muscarinic 1

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Other Names

  • U22 snoRNA host
  • long intergenic non-protein coding RNA 57
  • small nucleolar RNA host gene 1 (non-protein coding)

Gene Ontology Provided by GOA

Process Evidence Code Pubs
involved_in RNA processing IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
located_in nucleolus IEA
Inferred from Electronic Annotation
more info
 

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

RNA

  1. NR_003098.2 RNA Sequence

    Status: REVIEWED

    Source sequence(s)
    AA877654, BC011809, DA856235
    Related
    ENST00000539921.6
  2. NR_152575.1 RNA Sequence

    Status: REVIEWED

    Source sequence(s)
    AA877654, AK095849, BC011809, BC063571
    Related
    ENST00000658540.1
  3. NR_152576.1 RNA Sequence

    Status: REVIEWED

    Source sequence(s)
    AA877654, AK095849, BC063571
    Related
    ENST00000537925.5
  4. NR_152577.1 RNA Sequence

    Status: REVIEWED

    Source sequence(s)
    AP001160
  5. NR_152578.1 RNA Sequence

    Status: REVIEWED

    Source sequence(s)
    AA877654, AP001160, BC011809, BI828157
    Related
    ENST00000539975.5
  6. NR_152579.1 RNA Sequence

    Status: REVIEWED

    Source sequence(s)
    AA877654, BC011809, BG493280
  7. NR_152580.1 RNA Sequence

    Status: REVIEWED

    Source sequence(s)
    AA877654, BC011809, BG531729
  8. NR_152581.1 RNA Sequence

    Status: REVIEWED

    Source sequence(s)
    AA877654, BC011809, BM843108
    Related
    ENST00000541578.6
  9. NR_152582.1 RNA Sequence

    Status: REVIEWED

    Source sequence(s)
    AA877654, AP001160, BC011809, CB145643
    Related
    ENST00000537869.5
  10. NR_152583.1 RNA Sequence

    Status: REVIEWED

    Source sequence(s)
    AA877654, AK095849, AP001160, BC011809, BM745869
  11. NR_152584.1 RNA Sequence

    Status: REVIEWED

    Source sequence(s)
    AA877654, AK095849, BC011809, BC063571, CN337018
  12. NR_152585.1 RNA Sequence

    Status: REVIEWED

    Source sequence(s)
    AA877654, AK095849, BC011809, BC063571, BG167802

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.20211119

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000011.10 Reference GRCh38.p13 Primary Assembly

    Range
    62851978..62855885 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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