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VSIG2 V-set and immunoglobulin domain containing 2 [ Homo sapiens (human) ]

Gene ID: 23584, updated on 1-Jun-2020

Summary

Official Symbol
VSIG2provided by HGNC
Official Full Name
V-set and immunoglobulin domain containing 2provided by HGNC
Primary source
HGNC:HGNC:17149
See related
Ensembl:ENSG00000019102 MIM:606011
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
CTH; CTXL; 2210413P10Rik
Expression
Biased expression in stomach (RPKM 210.7), colon (RPKM 56.0) and 6 other tissues See more
Orthologs

Genomic context

See VSIG2 in Genome Data Viewer
Location:
11q24.2
Exon count:
7
Annotation release Status Assembly Chr Location
109.20200522 current GRCh38.p13 (GCF_000001405.39) 11 NC_000011.10 (124747474..124752255, complement)
105 previous assembly GRCh37.p13 (GCF_000001405.25) 11 NC_000011.9 (124617370..124622109, complement)

Chromosome 11 - NC_000011.10Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC107984405 Neighboring gene neurogranin Neighboring gene Sharpr-MPRA regulatory region 10895 Neighboring gene endothelial cell adhesion molecule Neighboring gene uncharacterized LOC101929340

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Gene Ontology Provided by GOA

Component Evidence Code Pubs
integral component of plasma membrane TAS
Traceable Author Statement
more info
PubMed 
membrane TAS
Traceable Author Statement
more info
PubMed 

General protein information

Preferred Names
V-set and immunoglobulin domain-containing protein 2
Names
CT-like protein
cortical thymocyte receptor (X. laevis CTX) like
cortical thymocyte-like protein

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001329920.2NP_001316849.1  V-set and immunoglobulin domain-containing protein 2 isoform 2 precursor

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) differs in the 3' UTR and coding sequence compared to variant 1. The resulting isoform (2) is shorter at the C-terminus compared to isoform 1.
    Source sequence(s)
    AK000460, BC012567
    Consensus CDS
    CCDS86258.1
    UniProtKB/Swiss-Prot
    Q96IQ7
    Related
    ENSP00000385013.1, ENST00000403470.1
  2. NM_014312.5NP_055127.2  V-set and immunoglobulin domain-containing protein 2 isoform 1 precursor

    See identical proteins and their annotated locations for NP_055127.2

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) encodes the longer isoform (1).
    Source sequence(s)
    BC007313, BC012567
    Consensus CDS
    CCDS8452.1
    UniProtKB/Swiss-Prot
    Q96IQ7
    Related
    ENSP00000318684.5, ENST00000326621.10
    Conserved Domains (2) summary
    pfam07686
    Location:31142
    V-set; Immunoglobulin V-set domain
    cd00096
    Location:164231
    Ig; Immunoglobulin domain

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000011.10 Reference GRCh38.p13 Primary Assembly

    Range
    124747474..124752255 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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