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Plscr4 phospholipid scramblase 4 [ Mus musculus (house mouse) ]

Gene ID: 235527, updated on 12-Aug-2018

Summary

Official Symbol
Plscr4provided by MGI
Official Full Name
phospholipid scramblase 4provided by MGI
Primary source
MGI:MGI:2143267
See related
Ensembl:ENSMUSG00000032377 Vega:OTTMUSG00000022961
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
AV245873
Expression
Broad expression in bladder adult (RPKM 12.3), lung adult (RPKM 8.2) and 15 other tissues See more
Orthologs

Genomic context

See Plscr4 in Genome Data Viewer
Location:
9; 9 E3.3
Exon count:
9
Annotation release Status Assembly Chr Location
106 current GRCm38.p4 (GCF_000001635.24) 9 NC_000075.6 (92457371..92492516)
Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 9 NC_000075.5 (92352216..92387354)

Chromosome 9 - NC_000075.6Genomic Context describing neighboring genes Neighboring gene phospholipid scramblase 2 Neighboring gene RIKEN cDNA 1700057G04 gene Neighboring gene predicted gene 15493 Neighboring gene RIKEN cDNA B430319G15 gene Neighboring gene procollagen lysine, 2-oxoglutarate 5-dioxygenase 2 Neighboring gene predicted gene 2495

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

General gene information

Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
CD4 receptor binding ISO
Inferred from Sequence Orthology
more info
 
enzyme binding ISO
Inferred from Sequence Orthology
more info
 
phospholipid scramblase activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Process Evidence Code Pubs
cellular response to lipopolysaccharide IEP
Inferred from Expression Pattern
more info
PubMed 
phospholipid scrambling IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Component Evidence Code Pubs
integral component of membrane IEA
Inferred from Electronic Annotation
more info
 
membrane IEA
Inferred from Electronic Annotation
more info
 
plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
plasma membrane ISO
Inferred from Sequence Orthology
more info
 

General protein information

Preferred Names
phospholipid scramblase 4
Names
PL scramblase 4
ca(2+)-dependent phospholipid scramblase 4

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_178711.3NP_848826.1  phospholipid scramblase 4

    See identical proteins and their annotated locations for NP_848826.1

    Status: VALIDATED

    Source sequence(s)
    AK035919, AK079413, AK082330
    Consensus CDS
    CCDS23407.1
    UniProtKB/Swiss-Prot
    P58196
    UniProtKB/TrEMBL
    Q8BV91
    Related
    ENSMUSP00000034941.7, OTTMUSP00000026427, ENSMUST00000034941.8, OTTMUST00000055245
    Conserved Domains (2) summary
    pfam03803
    Location:96318
    Scramblase; Scramblase
    pfam11029
    Location:27113
    DAZAP2; DAZ associated protein 2 (DAZAP2)

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 106

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm38.p4 C57BL/6J

Genomic

  1. NC_000075.6 Reference GRCm38.p4 C57BL/6J

    Range
    92457371..92492516
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006511130.2XP_006511193.1  phospholipid scramblase 4 isoform X1

    Conserved Domains (1) summary
    pfam03803
    Location:85307
    Scramblase; Scramblase
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