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TTC33 tetratricopeptide repeat domain 33 [ Homo sapiens (human) ]

Gene ID: 23548, updated on 12-Oct-2019

Summary

Official Symbol
TTC33provided by HGNC
Official Full Name
tetratricopeptide repeat domain 33provided by HGNC
Primary source
HGNC:HGNC:29959
See related
Ensembl:ENSG00000113638
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
OSRF
Expression
Ubiquitous expression in brain (RPKM 7.4), thyroid (RPKM 4.0) and 24 other tissues See more
Orthologs

Genomic context

See TTC33 in Genome Data Viewer
Location:
5p13.1
Exon count:
5
Annotation release Status Assembly Chr Location
109.20190905 current GRCh38.p13 (GCF_000001405.39) 5 NC_000005.10 (40711576..40755961, complement)
105 previous assembly GRCh37.p13 (GCF_000001405.25) 5 NC_000005.9 (40711678..40756072, complement)

Chromosome 5 - NC_000005.10Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC105374736 Neighboring gene uncharacterized LOC105374737 Neighboring gene prostaglandin E receptor 4 Neighboring gene HNF1 motif-containing MPRA enhancer 12 Neighboring gene protein kinase AMP-activated catalytic subunit alpha 1 Neighboring gene small nucleolar RNA, C/D box 72 Neighboring gene ribosomal protein L37

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Gene Ontology Provided by GOA

Function Evidence Code Pubs
protein binding IPI
Inferred from Physical Interaction
more info
PubMed 

General protein information

Preferred Names
tetratricopeptide repeat protein 33
Names
TPR repeat protein 33
osmosis responsive factor

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_012382.3NP_036514.1  tetratricopeptide repeat protein 33

    See identical proteins and their annotated locations for NP_036514.1

    Status: VALIDATED

    Source sequence(s)
    AC093264, AI174764, BC015701, BC036536, BE869916, BF509085, BM543635, BM689740, BQ922097, CR738110, DA518274, DA652008
    Consensus CDS
    CCDS3931.1
    UniProtKB/Swiss-Prot
    Q6PID6
    Related
    ENSP00000338533.4, ENST00000337702.5
    Conserved Domains (2) summary
    sd00006
    Location:5987
    TPR; TPR repeat [structural motif]
    cl27017
    Location:71192
    YfgC; Putative Zn-dependent protease, contains TPR repeats [General function prediction only]

RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 109.20190905

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000005.10 Reference GRCh38.p13 Primary Assembly

    Range
    40711576..40755961 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_011514003.3XP_011512305.1  tetratricopeptide repeat protein 33 isoform X1

    See identical proteins and their annotated locations for XP_011512305.1

    UniProtKB/Swiss-Prot
    Q6PID6
    Conserved Domains (2) summary
    sd00006
    Location:5987
    TPR; TPR repeat [structural motif]
    cl27017
    Location:71192
    YfgC; Putative Zn-dependent protease, contains TPR repeats [General function prediction only]
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