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Fez1 fasciculation and elongation protein zeta 1 (zygin I) [ Mus musculus (house mouse) ]

Gene ID: 235180, updated on 8-Jul-2018
Official Symbol
Fez1provided by MGI
Official Full Name
fasciculation and elongation protein zeta 1 (zygin I)provided by MGI
Primary source
MGI:MGI:2670976
See related
Ensembl:ENSMUSG00000032118 Vega:OTTMUSG00000034186
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
UNC76; UNC-76
Expression
Biased expression in CNS E18 (RPKM 83.7), cerebellum adult (RPKM 71.7) and 6 other tissues See more
Orthologs
See Fez1 in Genome Data Viewer
Location:
9; 9 A4
Exon count:
14
Annotation release Status Assembly Chr Location
106 current GRCm38.p4 (GCF_000001635.24) 9 NC_000075.6 (36821891..36878927)
Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 9 NC_000075.5 (36651244..36686225)

Chromosome 9 - NC_000075.6Genomic Context describing neighboring genes Neighboring gene STT3, subunit of the oligosaccharyltransferase complex, homolog A (S. cerevisiae) Neighboring gene predicted gene, 26787 Neighboring gene etoposide induced 2.4 mRNA Neighboring gene predicted gene 27219 Neighboring gene Pbx/knotted 1 homeobox 2 Neighboring gene predicted gene, 34652 Neighboring gene predicted gene, 34538

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
Products Interactant Other Gene Complex Source Pubs Description

Markers

Homology

Clone Names

  • MGC19293

Gene Ontology Provided by MGI

Function Evidence Code Pubs
gamma-tubulin binding IDA
Inferred from Direct Assay
more info
PubMed 
protein N-terminus binding ISO
Inferred from Sequence Orthology
more info
 
protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
protein kinase C binding ISO
Inferred from Sequence Orthology
more info
 
Process Evidence Code Pubs
establishment of cell polarity ISO
Inferred from Sequence Orthology
more info
 
establishment of mitochondrion localization ISO
Inferred from Sequence Orthology
more info
 
mitochondrion morphogenesis ISO
Inferred from Sequence Orthology
more info
 
negative regulation of autophagosome assembly ISO
Inferred from Sequence Orthology
more info
 
positive regulation of anterograde axonal transport of mitochondrion ISO
Inferred from Sequence Orthology
more info
 
positive regulation of neuron differentiation ISO
Inferred from Sequence Orthology
more info
 
positive regulation of neuron projection development ISO
Inferred from Sequence Orthology
more info
 
Component Evidence Code Pubs
Golgi apparatus ISO
Inferred from Sequence Orthology
more info
 
axon IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
axon ISO
Inferred from Sequence Orthology
more info
 
cell projection ISO
Inferred from Sequence Orthology
more info
 
centrosome IDA
Inferred from Direct Assay
more info
PubMed 
cytoplasm IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
cytoplasm IDA
Inferred from Direct Assay
more info
PubMed 
cytoplasm ISO
Inferred from Sequence Orthology
more info
 
cytoskeleton IEA
Inferred from Electronic Annotation
more info
 
dendrite ISO
Inferred from Sequence Orthology
more info
 
growth cone ISO
Inferred from Sequence Orthology
more info
 
membrane IEA
Inferred from Electronic Annotation
more info
 
microtubule IEA
Inferred from Electronic Annotation
more info
 
colocalizes_with mitochondrion ISO
Inferred from Sequence Orthology
more info
 
neuronal cell body ISO
Inferred from Sequence Orthology
more info
 
plasma membrane ISO
Inferred from Sequence Orthology
more info
 
Preferred Names
fasciculation and elongation protein zeta-1
Names
zygin I
zygin-1

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001357610.1NP_001344539.1  fasciculation and elongation protein zeta-1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) represents the longest transcript. All six transcripts encode the same protein.
    Source sequence(s)
    CT009699, CT955982
    Conserved Domains (1) summary
    pfam07763
    Location:58297
    FEZ; FEZ-like protein
  2. NM_001357611.1NP_001344540.1  fasciculation and elongation protein zeta-1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) differs in the 5' UTR compared to variant 1. All six variants encode the same protein.
    Source sequence(s)
    CT009699
    Conserved Domains (1) summary
    pfam07763
    Location:58297
    FEZ; FEZ-like protein
  3. NM_001357612.1NP_001344541.1  fasciculation and elongation protein zeta-1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (3) differs in the 5' UTR compared to variant 1. All six variants encode the same protein.
    Source sequence(s)
    CT009699, CT955982
    Conserved Domains (1) summary
    pfam07763
    Location:58297
    FEZ; FEZ-like protein
  4. NM_001357613.1NP_001344542.1  fasciculation and elongation protein zeta-1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (5) differs in the 5' UTR compared to variant 1. All six variants encode the same protein.
    Source sequence(s)
    CT009699
    Conserved Domains (1) summary
    pfam07763
    Location:58297
    FEZ; FEZ-like protein
  5. NM_001357614.1NP_001344543.1  fasciculation and elongation protein zeta-1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (6) differs in the 5' UTR compared to variant 1. All six variants encode the same protein.
    Source sequence(s)
    CT009699
    Conserved Domains (1) summary
    pfam07763
    Location:58297
    FEZ; FEZ-like protein
  6. NM_183171.5NP_898994.2  fasciculation and elongation protein zeta-1

    See identical proteins and their annotated locations for NP_898994.2

    Status: VALIDATED

    Description
    Transcript Variant: This variant (4) differs in the 5' UTR compared to variant 1. All six variants encode the same protein.
    Source sequence(s)
    CT009699
    Consensus CDS
    CCDS40581.1
    UniProtKB/Swiss-Prot
    Q8K0X8
    Related
    ENSMUSP00000126072.1, ENSMUST00000163816.7
    Conserved Domains (1) summary
    pfam07763
    Location:58297
    FEZ; FEZ-like protein

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 106

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm38.p4 C57BL/6J

Genomic

  1. NC_000075.6 Reference GRCm38.p4 C57BL/6J

    Range
    36821891..36878927
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_017313312.1XP_017168801.1  fasciculation and elongation protein zeta-1 isoform X1

    UniProtKB/Swiss-Prot
    Q8K0X8
    Conserved Domains (1) summary
    pfam07763
    Location:58297
    FEZ; FEZ-like protein
  2. XM_006510229.3XP_006510292.1  fasciculation and elongation protein zeta-1 isoform X1

    UniProtKB/Swiss-Prot
    Q8K0X8
    Conserved Domains (1) summary
    pfam07763
    Location:58297
    FEZ; FEZ-like protein
  3. XM_006510227.3XP_006510290.1  fasciculation and elongation protein zeta-1 isoform X1

    UniProtKB/Swiss-Prot
    Q8K0X8
    Related
    ENSMUSP00000034630.8, OTTMUSP00000046953, ENSMUST00000034630.14, OTTMUST00000086695
    Conserved Domains (1) summary
    pfam07763
    Location:58297
    FEZ; FEZ-like protein
  4. XM_017313313.1XP_017168802.1  fasciculation and elongation protein zeta-1 isoform X1

    UniProtKB/Swiss-Prot
    Q8K0X8
    Conserved Domains (1) summary
    pfam07763
    Location:58297
    FEZ; FEZ-like protein
  5. XM_006510228.3XP_006510291.1  fasciculation and elongation protein zeta-1 isoform X1

    UniProtKB/Swiss-Prot
    Q8K0X8
    Conserved Domains (1) summary
    pfam07763
    Location:58297
    FEZ; FEZ-like protein
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