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Zfp809 zinc finger protein 809 [ Mus musculus (house mouse) ]

Gene ID: 235047, updated on 12-May-2024

Summary

Official Symbol
Zfp809provided by MGI
Official Full Name
zinc finger protein 809provided by MGI
Primary source
MGI:MGI:2143362
See related
Ensembl:ENSMUSG00000057982 AllianceGenome:MGI:2143362
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
C330026E23
Summary
Enables sequence-specific DNA binding activity. Acts upstream of or within innate immune response and negative regulation of single stranded viral RNA replication via double stranded DNA intermediate. Located in nucleus. Is expressed in early conceptus and genitourinary system. [provided by Alliance of Genome Resources, Apr 2022]
Expression
Ubiquitous expression in bladder adult (RPKM 9.1), placenta adult (RPKM 4.0) and 28 other tissues See more
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Genomic context

See Zfp809 in Genome Data Viewer
Location:
9 A3; 9 8.65 cM
Exon count:
8
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 9 NC_000075.7 (22136980..22165413)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 9 NC_000075.6 (22225667..22254117)

Chromosome 9 - NC_000075.7Genomic Context describing neighboring genes Neighboring gene RIKEN cDNA 1810064F22 gene Neighboring gene zinc finger protein 791 pseudogene Neighboring gene STARR-positive B cell enhancer ABC_E1381 Neighboring gene STARR-seq mESC enhancer starr_23539 Neighboring gene zinc finger protein 599 Neighboring gene STARR-positive B cell enhancer ABC_E1382 Neighboring gene predicted gene, 39307 Neighboring gene predicted gene, 39308

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Endonuclease-mediated (1) 
  • Gene trapped (1) 
  • Targeted (2)  1 citation

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Clone Names

  • MGC117587

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables DNA-binding transcription factor activity, RNA polymerase II-specific IBA
Inferred from Biological aspect of Ancestor
more info
 
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IBA
Inferred from Biological aspect of Ancestor
more info
 
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
 
enables protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
enables sequence-specific DNA binding IDA
Inferred from Direct Assay
more info
PubMed 
Component Evidence Code Pubs
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
 
located_in nucleus IDA
Inferred from Direct Assay
more info
PubMed 

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001164624.1NP_001158096.1  zinc finger protein 809 isoform 2

    See identical proteins and their annotated locations for NP_001158096.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) contains a different segment for its 3' coding region and 3' UTR, compared to variant 1. The resulting protein (isoform 2) has a shorter and distinct C-terminus when it is compared to isoform 2.
    Source sequence(s)
    AK049344, BY729060, BY764604
    Consensus CDS
    CCDS90519.1
    UniProtKB/Swiss-Prot
    G3X9G7
    Related
    ENSMUSP00000151180.2, ENSMUST00000215618.2
    Conserved Domains (6) summary
    smart00349
    Location:464
    KRAB; krueppel associated box
    COG5048
    Location:125348
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:215235
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam00096
    Location:213235
    zf-C2H2; Zinc finger, C2H2 type
    pfam01352
    Location:443
    KRAB; KRAB box
    pfam13465
    Location:255280
    zf-H2C2_2; Zinc-finger double domain
  2. NM_172763.3NP_766351.3  zinc finger protein 809 isoform 1

    See identical proteins and their annotated locations for NP_766351.3

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) encodes the longer protein (isoform 1).
    Source sequence(s)
    BC099418, BY729060, CK389669
    Consensus CDS
    CCDS40560.1
    UniProtKB/Swiss-Prot
    G3X9G7, Q4KL58, Q8BIJ2
    Related
    ENSMUSP00000072286.8, ENSMUST00000072465.9
    Conserved Domains (6) summary
    smart00349
    Location:464
    KRAB; krueppel associated box
    COG5048
    Location:125348
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:215235
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam00096
    Location:213235
    zf-C2H2; Zinc finger, C2H2 type
    pfam01352
    Location:443
    KRAB; KRAB box
    pfam13465
    Location:255280
    zf-H2C2_2; Zinc-finger double domain

RNA

  1. NR_028420.1 RNA Sequence

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) has multiple differences, compared to variant 1. This variant is represented as non-coding because the use of the 5'-most translational start codon, as used in variant 1, renders the transcript a candidate for nonsense-mediated mRNA decay (NMD).
    Source sequence(s)
    AK089532, BB658893, BY729060
    Related
    ENSMUST00000213371.2

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000075.7 Reference GRCm39 C57BL/6J

    Range
    22136980..22165413
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006510188.5XP_006510251.1  zinc finger protein 809 isoform X1

    Conserved Domains (3) summary
    smart00349
    Location:464
    KRAB; krueppel associated box
    COG5048
    Location:125348
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:215235
    ZF_C2H2; C2H2 Zn finger [structural motif]
  2. XM_006510189.5XP_006510252.1  zinc finger protein 809 isoform X2

    Conserved Domains (3) summary
    smart00349
    Location:464
    KRAB; krueppel associated box
    COG5048
    Location:125348
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:215235
    ZF_C2H2; C2H2 Zn finger [structural motif]
  3. XM_017313302.3XP_017168791.1  zinc finger protein 809 isoform X3

    Conserved Domains (2) summary
    COG5048
    Location:4157
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:2444
    ZF_C2H2; C2H2 Zn finger [structural motif]