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Ppan peter pan homolog [ Mus musculus (house mouse) ]

Gene ID: 235036, updated on 11-Apr-2024

Summary

Official Symbol
Ppanprovided by MGI
Official Full Name
peter pan homologprovided by MGI
Primary source
MGI:MGI:2178445
See related
Ensembl:ENSMUSG00000004100 AllianceGenome:MGI:2178445
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
SSF1; A230087P06Rik
Summary
Predicted to enable rRNA binding activity. Predicted to be involved in ribosomal large subunit assembly. Predicted to act upstream of or within regulation of cell growth by extracellular stimulus. Predicted to be located in nucleus. Predicted to be part of preribosome, large subunit precursor. Orthologous to several human genes including PPAN-P2RY11 (PPAN-P2RY11 readthrough). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Ubiquitous expression in liver E14.5 (RPKM 44.9), ovary adult (RPKM 43.6) and 28 other tissues See more
Orthologs
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Genomic context

See Ppan in Genome Data Viewer
Location:
9 A3; 9 7.66 cM
Exon count:
11
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 9 NC_000075.7 (20799471..20803475)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 9 NC_000075.6 (20888175..20892179)

Chromosome 9 - NC_000075.7Genomic Context describing neighboring genes Neighboring gene predicted gene, 39300 Neighboring gene shiftless antiviral inhibitor of ribosomal frameshifting Neighboring gene angiopoietin-like 6 Neighboring gene STARR-positive B cell enhancer ABC_E6717 Neighboring gene predicted gene, 24067 Neighboring gene predicted gene, 23008 Neighboring gene STARR-positive B cell enhancer ABC_E3817 Neighboring gene eukaryotic translation initiation factor 3, subunit G Neighboring gene DNA methyltransferase 1 Neighboring gene microRNA 7081

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables rRNA binding IBA
Inferred from Biological aspect of Ancestor
more info
 
Process Evidence Code Pubs
involved_in rRNA processing IEA
Inferred from Electronic Annotation
more info
 
acts_upstream_of_or_within regulation of cell growth by extracellular stimulus ISO
Inferred from Sequence Orthology
more info
PubMed 
involved_in ribosomal large subunit assembly IBA
Inferred from Biological aspect of Ancestor
more info
 
Component Evidence Code Pubs
located_in nucleus ISO
Inferred from Sequence Orthology
more info
 
part_of preribosome, large subunit precursor IBA
Inferred from Biological aspect of Ancestor
more info
 

General protein information

Preferred Names
suppressor of SWI4 1 homolog
Names
second-step splicing factor 1
ssf-1
suppressor of sterile four 1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_145610.2NP_663585.2  suppressor of SWI4 1 homolog

    See identical proteins and their annotated locations for NP_663585.2

    Status: VALIDATED

    Source sequence(s)
    AK039027, BB749945, CJ077201
    Consensus CDS
    CCDS22887.1
    UniProtKB/Swiss-Prot
    Q8BYM4, Q91YU8
    Related
    ENSMUSP00000004203.6, ENSMUST00000004203.6
    Conserved Domains (2) summary
    pfam04427
    Location:35285
    Brix; Brix domain
    cl00935
    Location:270341
    Brix; Brix domain

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000075.7 Reference GRCm39 C57BL/6J

    Range
    20799471..20803475
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)