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Slc38a8 solute carrier family 38, member 8 [ Mus musculus (house mouse) ]

Gene ID: 234788, updated on 19-Jun-2024

Summary

Official Symbol
Slc38a8provided by MGI
Official Full Name
solute carrier family 38, member 8provided by MGI
Primary source
MGI:MGI:2685433
See related
Ensembl:ENSMUSG00000034224 AllianceGenome:MGI:2685433
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Gm587
Summary
Predicted to enable amino acid transmembrane transporter activity. Predicted to be involved in amino acid transmembrane transport. Predicted to act upstream of or within amino acid transport and sodium ion transport. Predicted to be located in membrane. Predicted to be integral component of membrane. Orthologous to human SLC38A8 (solute carrier family 38 member 8). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Low expression observed in reference dataset See more
Orthologs
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Genomic context

See Slc38a8 in Genome Data Viewer
Location:
8 E1; 8 67.8 cM
Exon count:
12
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 8 NC_000074.7 (120206313..120228503, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 8 NC_000074.6 (119479574..119501698, complement)

Chromosome 8 - NC_000074.7Genomic Context describing neighboring genes Neighboring gene oxidative stress induced growth inhibitor 1 Neighboring gene N-terminal EF-hand calcium binding protein 2 Neighboring gene predicted gene, 53462 Neighboring gene STARR-seq mESC enhancer starr_22850 Neighboring gene membrane-bound transcription factor peptidase, site 1 Neighboring gene STARR-seq mESC enhancer starr_22853 Neighboring gene STARR-positive B cell enhancer mm9_chr8:122082621-122082922 Neighboring gene CapStarr-seq enhancer MGSCv37_chr8:122087691-122087878 Neighboring gene CapStarr-seq enhancer MGSCv37_chr8:122087910-122088232 Neighboring gene CapStarr-seq enhancer MGSCv37_chr8:122093859-122094132 Neighboring gene hydroxysteroid dehydrogenase like 1

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Endonuclease-mediated (6)  1 citation
  • Gene trapped (1) 

General gene information

Markers

Clone Names

  • MGC113805

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables L-amino acid transmembrane transporter activity IBA
Inferred from Biological aspect of Ancestor
more info
 
Component Evidence Code Pubs
located_in cell projection IEA
Inferred from Electronic Annotation
more info
 
is_active_in cellular_component ND
No biological Data available
more info
 
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 
is_active_in membrane IBA
Inferred from Biological aspect of Ancestor
more info
 

General protein information

Preferred Names
solute carrier family 38 member 8
Names
amino acid transporter SLC38A8
putative sodium-coupled neutral amino acid transporter 8

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001009950.2NP_001009950.1  solute carrier family 38 member 8

    See identical proteins and their annotated locations for NP_001009950.1

    Status: VALIDATED

    Source sequence(s)
    AC140672, AC166781
    Consensus CDS
    CCDS22706.1
    UniProtKB/Swiss-Prot
    Q5HZH7
    Related
    ENSMUSP00000038438.9, ENSMUST00000036748.15
    Conserved Domains (2) summary
    COG0814
    Location:23429
    SdaC; Amino acid permease [Amino acid transport and metabolism]
    cl00456
    Location:23421
    SLC5-6-like_sbd; Solute carrier families 5 and 6-like; solute binding domain

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000074.7 Reference GRCm39 C57BL/6J

    Range
    120206313..120228503 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_011248368.2XP_011246670.1  solute carrier family 38 member 8 isoform X1

    See identical proteins and their annotated locations for XP_011246670.1

    Conserved Domains (1) summary
    cl00456
    Location:1322
    SLC5-6-like_sbd; Solute carrier families 5 and 6-like; solute binding domain