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Tmem41b transmembrane protein 41B [ Mus musculus (house mouse) ]

Gene ID: 233724, updated on 21-May-2024

Summary

Official Symbol
Tmem41bprovided by MGI
Official Full Name
transmembrane protein 41Bprovided by MGI
Primary source
MGI:MGI:1289225
See related
Ensembl:ENSMUSG00000047554 AllianceGenome:MGI:1289225
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
D7Ertd70e; D7Ertd743e; 1500015G02Rik; 1500031M19Rik
Summary
Predicted to be involved in autophagosome assembly. Predicted to act upstream of or within autophagy and nervous system development. Located in mitochondria-associated endoplasmic reticulum membrane. Is expressed in embryo. Orthologous to human TMEM41B (transmembrane protein 41B). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Ubiquitous expression in placenta adult (RPKM 10.3), cerebellum adult (RPKM 8.5) and 28 other tissues See more
Orthologs
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Genomic context

See Tmem41b in Genome Data Viewer
Location:
7 E3; 7 57.69 cM
Exon count:
8
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 7 NC_000073.7 (109570422..109586011, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 7 NC_000073.6 (109971215..109986804, complement)

Chromosome 7 - NC_000073.7Genomic Context describing neighboring genes Neighboring gene signal peptide, CUB domain, EGF-like 2 Neighboring gene STARR-seq mESC enhancer starr_19808 Neighboring gene STARR-seq mESC enhancer starr_19809 Neighboring gene DENN domain containing 5A Neighboring gene STARR-seq mESC enhancer starr_19810 Neighboring gene CapStarr-seq enhancer MGSCv37_chr7:117129931-117130114 Neighboring gene RIKEN cDNA 1600010M07 gene Neighboring gene STARR-seq mESC enhancer starr_19812 Neighboring gene predicted gene, 23100 Neighboring gene predicted gene, 25636 Neighboring gene importin 7

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Clone Names

  • MGC38847

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables phospholipid scramblase activity ISO
Inferred from Sequence Orthology
more info
 
Process Evidence Code Pubs
involved_in autophagosome assembly IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in autophagosome assembly ISO
Inferred from Sequence Orthology
more info
 
acts_upstream_of_or_within autophagy IEA
Inferred from Electronic Annotation
more info
 
involved_in intracellular lipid transport ISO
Inferred from Sequence Orthology
more info
 
acts_upstream_of_or_within lipid transport IEA
Inferred from Electronic Annotation
more info
 
involved_in modulation by host of viral RNA genome replication ISO
Inferred from Sequence Orthology
more info
 
acts_upstream_of_or_within nervous system development IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
located_in endoplasmic reticulum IEA
Inferred from Electronic Annotation
more info
 
is_active_in endoplasmic reticulum membrane IBA
Inferred from Biological aspect of Ancestor
more info
 
is_active_in endoplasmic reticulum membrane ISO
Inferred from Sequence Orthology
more info
 
located_in membrane IEA
Inferred from Electronic Annotation
more info
 
located_in mitochondria-associated endoplasmic reticulum membrane contact site IDA
Inferred from Direct Assay
more info
PubMed 
located_in mitochondria-associated endoplasmic reticulum membrane contact site ISO
Inferred from Sequence Orthology
more info
 

General protein information

Preferred Names
transmembrane protein 41B
Names
Stasimon
protein stasimon

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_153525.5NP_705745.3  transmembrane protein 41B

    See identical proteins and their annotated locations for NP_705745.3

    Status: PROVISIONAL

    Source sequence(s)
    AC140235
    Consensus CDS
    CCDS21742.1
    UniProtKB/Swiss-Prot
    Q3TKT0, Q3TLK6, Q8C1X2, Q8CBS5, Q8CBU5, Q8K1A5
    Related
    ENSMUSP00000091641.6, ENSMUST00000094097.12
    Conserved Domains (1) summary
    pfam09335
    Location:129248
    VTT; VMP1, TMEM41, and TVP38 (VTT) domain

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000073.7 Reference GRCm39 C57BL/6J

    Range
    109570422..109586011 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_030242499.1XP_030098359.1  transmembrane protein 41B isoform X1

    UniProtKB/Swiss-Prot
    Q3TKT0, Q3TLK6, Q8C1X2, Q8CBS5, Q8CBU5, Q8K1A5
    Related
    ENSMUSP00000112574.2, ENSMUST00000118429.8
    Conserved Domains (1) summary
    pfam09335
    Location:129248
    VTT; VMP1, TMEM41, and TVP38 (VTT) domain