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Gdpd5 glycerophosphodiester phosphodiesterase domain containing 5 [ Mus musculus (house mouse) ]

Gene ID: 233552, updated on 25-Nov-2021

Summary

Official Symbol
Gdpd5provided by MGI
Official Full Name
glycerophosphodiester phosphodiesterase domain containing 5provided by MGI
Primary source
MGI:MGI:2686926
See related
Ensembl:ENSMUSG00000035314
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Gde2; BC024955
Expression
Ubiquitous expression in ovary adult (RPKM 14.1), whole brain E14.5 (RPKM 14.1) and 24 other tissues See more
Orthologs
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Genomic context

See Gdpd5 in Genome Data Viewer
Location:
7; 7 E1
Exon count:
21
Annotation release Status Assembly Chr Location
109 current GRCm39 (GCF_000001635.27) 7 NC_000073.7 (99027976..99111082)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 7 NC_000073.6 (99381463..99461875)
Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 7 NC_000073.5 (106530059..106609494)

Chromosome 7 - NC_000073.7Genomic Context describing neighboring genes Neighboring gene microtubule-associated protein 6 Neighboring gene predicted gene, 40449 Neighboring gene serine (or cysteine) peptidase inhibitor, clade H, member 1 Neighboring gene kelch-like 35 Neighboring gene small nucleolar RNA, C/D box 14B Neighboring gene ribosomal protein S3

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)

General gene information

Markers

Homology

Clone Names

  • MGC31332, MGC37148

Gene Ontology Provided by MGI

Process Evidence Code Pubs
acts_upstream_of_or_within cerebral cortex neuron differentiation IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in lipid metabolic process IEA
Inferred from Electronic Annotation
more info
 
involved_in negative regulation of Notch signaling pathway IDA
Inferred from Direct Assay
more info
PubMed 
acts_upstream_of_or_within negative regulation of Notch signaling pathway IMP
Inferred from Mutant Phenotype
more info
PubMed 
acts_upstream_of_or_within negative regulation of Notch signaling pathway ISO
Inferred from Sequence Orthology
more info
 
acts_upstream_of_or_within nervous system development IEA
Inferred from Electronic Annotation
more info
 
acts_upstream_of_or_within neuron projection development IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in positive regulation of cell cycle IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in positive regulation of neuron differentiation IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
acts_upstream_of_or_within positive regulation of neuron differentiation IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in positive regulation of neuron differentiation IMP
Inferred from Mutant Phenotype
more info
PubMed 
acts_upstream_of_or_within regulation of timing of cell differentiation IMP
Inferred from Mutant Phenotype
more info
PubMed 
acts_upstream_of_or_within spinal cord motor neuron differentiation IMP
Inferred from Mutant Phenotype
more info
PubMed 
Component Evidence Code Pubs
located_in axon IDA
Inferred from Direct Assay
more info
PubMed 
located_in cell projection IEA
Inferred from Electronic Annotation
more info
 
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 
located_in endoplasmic reticulum membrane TAS
Traceable Author Statement
more info
 
located_in integral component of membrane IEA
Inferred from Electronic Annotation
more info
 
is_active_in membrane IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
located_in membrane IDA
Inferred from Direct Assay
more info
PubMed 
located_in neuronal cell body IDA
Inferred from Direct Assay
more info
PubMed 
located_in perinuclear endoplasmic reticulum IDA
Inferred from Direct Assay
more info
PubMed 
is_active_in plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 

General protein information

Preferred Names
glycerophosphodiester phosphodiesterase domain-containing protein 5
Names
glycerophosphocholine phosphodiesterase GDPD5
glycerophosphodiester phosphodiesterase 2
phosphoinositide phospholipase C GDPD5
NP_001349095.1
NP_001349096.1
NP_001349097.1
NP_958740.2
XP_006507696.1
XP_006507697.1
XP_006507698.1
XP_006507700.1
XP_006507702.1
XP_011240040.1
XP_030098348.1
XP_030098349.1
XP_036008885.1
XP_036008886.1
XP_036008887.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001362166.1NP_001349095.1  glycerophosphodiester phosphodiesterase domain-containing protein 5 isoform 1

    Status: VALIDATED

    Source sequence(s)
    AC115858, AC158748
    Consensus CDS
    CCDS21481.1
    Conserved Domains (1) summary
    cl14615
    Location:227576
    PI-PLCc_GDPD_SF; Catalytic domain of phosphoinositide-specific phospholipase C-like phosphodiesterases superfamily
  2. NM_001362167.1NP_001349096.1  glycerophosphodiester phosphodiesterase domain-containing protein 5 isoform 2

    Status: VALIDATED

    Source sequence(s)
    AC115858, AC158748
    Consensus CDS
    CCDS90276.1
    Related
    ENSMUSP00000150361.2, ENSMUST00000213887.2
    Conserved Domains (1) summary
    cl14615
    Location:227581
    PI-PLCc_GDPD_SF; Catalytic domain of phosphoinositide-specific phospholipase C-like phosphodiesterases superfamily
  3. NM_001362168.1NP_001349097.1  glycerophosphodiester phosphodiesterase domain-containing protein 5 isoform 3

    Status: VALIDATED

    Source sequence(s)
    AC115858, AC158748
    Conserved Domains (1) summary
    cl14615
    Location:170524
    PI-PLCc_GDPD_SF; Catalytic domain of phosphoinositide-specific phospholipase C-like phosphodiesterases superfamily
  4. NM_201352.3NP_958740.2  glycerophosphodiester phosphodiesterase domain-containing protein 5 isoform 1

    See identical proteins and their annotated locations for NP_958740.2

    Status: VALIDATED

    Source sequence(s)
    AC115858, AK141189, BC082585, CO039911
    Consensus CDS
    CCDS21481.1
    UniProtKB/Swiss-Prot
    Q640M6
    Related
    ENSMUSP00000036175.9, ENSMUST00000037528.10
    Conserved Domains (1) summary
    cl14615
    Location:227576
    PI-PLCc_GDPD_SF; Catalytic domain of phosphoinositide-specific phospholipase C-like phosphodiesterases superfamily

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000073.7 Reference GRCm39 C57BL/6J

    Range
    99027976..99111082
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_011241738.3XP_011240040.1  glycerophosphodiester phosphodiesterase domain-containing protein 5 isoform X1

    See identical proteins and their annotated locations for XP_011240040.1

    UniProtKB/TrEMBL
    A0A1L1STK0
    Conserved Domains (1) summary
    cl14615
    Location:227581
    PI-PLCc_GDPD_SF; Catalytic domain of phosphoinositide-specific phospholipase C-like phosphodiesterases superfamily
  2. XM_036152992.1XP_036008885.1  glycerophosphodiester phosphodiesterase domain-containing protein 5 isoform X2

    Conserved Domains (1) summary
    cl14615
    Location:227576
    PI-PLCc_GDPD_SF; Catalytic domain of phosphoinositide-specific phospholipase C-like phosphodiesterases superfamily
  3. XM_006507634.3XP_006507697.1  glycerophosphodiester phosphodiesterase domain-containing protein 5 isoform X1

    See identical proteins and their annotated locations for XP_006507697.1

    UniProtKB/TrEMBL
    A0A1L1STK0
    Conserved Domains (1) summary
    cl14615
    Location:227581
    PI-PLCc_GDPD_SF; Catalytic domain of phosphoinositide-specific phospholipase C-like phosphodiesterases superfamily
  4. XM_006507633.3XP_006507696.1  glycerophosphodiester phosphodiesterase domain-containing protein 5 isoform X1

    See identical proteins and their annotated locations for XP_006507696.1

    UniProtKB/TrEMBL
    A0A1L1STK0
    Conserved Domains (1) summary
    cl14615
    Location:227581
    PI-PLCc_GDPD_SF; Catalytic domain of phosphoinositide-specific phospholipase C-like phosphodiesterases superfamily
  5. XM_006507635.3XP_006507698.1  glycerophosphodiester phosphodiesterase domain-containing protein 5 isoform X3

    Conserved Domains (1) summary
    cl14615
    Location:207561
    PI-PLCc_GDPD_SF; Catalytic domain of phosphoinositide-specific phospholipase C-like phosphodiesterases superfamily
  6. XM_036152993.1XP_036008886.1  glycerophosphodiester phosphodiesterase domain-containing protein 5 isoform X4

    Conserved Domains (1) summary
    cl14615
    Location:170519
    PI-PLCc_GDPD_SF; Catalytic domain of phosphoinositide-specific phospholipase C-like phosphodiesterases superfamily
  7. XM_030242488.2XP_030098348.1  glycerophosphodiester phosphodiesterase domain-containing protein 5 isoform X5

    Conserved Domains (1) summary
    cl14615
    Location:150504
    PI-PLCc_GDPD_SF; Catalytic domain of phosphoinositide-specific phospholipase C-like phosphodiesterases superfamily
  8. XM_006507637.3XP_006507700.1  glycerophosphodiester phosphodiesterase domain-containing protein 5 isoform X6

    Conserved Domains (1) summary
    cl14615
    Location:148502
    PI-PLCc_GDPD_SF; Catalytic domain of phosphoinositide-specific phospholipase C-like phosphodiesterases superfamily
  9. XM_036152994.1XP_036008887.1  glycerophosphodiester phosphodiesterase domain-containing protein 5 isoform X7

    Conserved Domains (1) summary
    cl14615
    Location:148497
    PI-PLCc_GDPD_SF; Catalytic domain of phosphoinositide-specific phospholipase C-like phosphodiesterases superfamily
  10. XM_030242489.2XP_030098349.1  glycerophosphodiester phosphodiesterase domain-containing protein 5 isoform X8

    Conserved Domains (1) summary
    cl14615
    Location:128482
    PI-PLCc_GDPD_SF; Catalytic domain of phosphoinositide-specific phospholipase C-like phosphodiesterases superfamily
  11. XM_006507639.3XP_006507702.1  glycerophosphodiester phosphodiesterase domain-containing protein 5 isoform X9

    Conserved Domains (1) summary
    cl14615
    Location:227316
    PI-PLCc_GDPD_SF; Catalytic domain of phosphoinositide-specific phospholipase C-like phosphodiesterases superfamily
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