U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Mogat2 monoacylglycerol O-acyltransferase 2 [ Mus musculus (house mouse) ]

Gene ID: 233549, updated on 5-Jan-2023

Summary

Official Symbol
Mogat2provided by MGI
Official Full Name
monoacylglycerol O-acyltransferase 2provided by MGI
Primary source
MGI:MGI:2663253
See related
Ensembl:ENSMUSG00000052396 AllianceGenome:MGI:2663253
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
MGAT2; Mgat1l; DGAT2L5
Summary
Enables 2-acylglycerol O-acyltransferase activity and acetyltransferase activity. Acts upstream of or within diacylglycerol biosynthetic process; intestinal absorption; and triglyceride biosynthetic process. Predicted to be located in perinuclear endoplasmic reticulum membrane. Is expressed in several structures, including embryo endoderm; liver; metanephros; somite; and yolk sac endoderm. Orthologous to human MOGAT2 (monoacylglycerol O-acyltransferase 2). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Biased expression in duodenum adult (RPKM 179.6), large intestine adult (RPKM 123.9) and 5 other tissues See more
Orthologs
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

See Mogat2 in Genome Data Viewer
Location:
7; 7 E1
Exon count:
7
Annotation release Status Assembly Chr Location
109 current GRCm39 (GCF_000001635.27) 7 NC_000073.7 (98868291..98887818, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 7 NC_000073.6 (99219084..99238611, complement)

Chromosome 7 - NC_000073.7Genomic Context describing neighboring genes Neighboring gene UV radiation resistance associated gene Neighboring gene predicted gene, 33882 Neighboring gene diacylglycerol O-acyltransferase 2 Neighboring gene WW domain containing adaptor with coiled-coil pseudogene Neighboring gene predicted gene, 34062

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Targeted (4)  1 citation
  • Endonuclease-mediated (3) 

Pathways from PubChem

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables 2-acylglycerol O-acyltransferase activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables 2-acylglycerol O-acyltransferase activity IDA
Inferred from Direct Assay
more info
PubMed 
enables 2-acylglycerol O-acyltransferase activity ISO
Inferred from Sequence Orthology
more info
PubMed 
enables O-acyltransferase activity IEA
Inferred from Electronic Annotation
more info
 
enables acetyltransferase activity IDA
Inferred from Direct Assay
more info
PubMed 
enables acyltransferase activity IEA
Inferred from Electronic Annotation
more info
 
enables diacylglycerol O-acyltransferase activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables transferase activity IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 
located_in endoplasmic reticulum ISO
Inferred from Sequence Orthology
more info
PubMed 
is_active_in endoplasmic reticulum membrane IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
located_in membrane IEA
Inferred from Electronic Annotation
more info
 
located_in perinuclear endoplasmic reticulum membrane ISO
Inferred from Sequence Orthology
more info
 

General protein information

Preferred Names
2-acylglycerol O-acyltransferase 2
Names
acyl CoA:monoacylglycerol acyltransferase 2
diacylglycerol acyltransferase 2-like protein 5
NP_803231.1
XP_011240039.1

NCBI Reference Sequences (RefSeq)

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_177448.4NP_803231.1  2-acylglycerol O-acyltransferase 2

    See identical proteins and their annotated locations for NP_803231.1

    Status: VALIDATED

    Source sequence(s)
    AK133854, BC052831
    Consensus CDS
    CCDS21478.1
    UniProtKB/Swiss-Prot
    Q80W94
    UniProtKB/TrEMBL
    A0A8C6I777
    Related
    ENSMUSP00000064041.8, ENSMUST00000064231.8
    Conserved Domains (1) summary
    cl17185
    Location:41333
    LPLAT; Lysophospholipid acyltransferases (LPLATs) of glycerophospholipid biosynthesis

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000073.7 Reference GRCm39 C57BL/6J

    Range
    98868291..98887818 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_011241737.1XP_011240039.1  2-acylglycerol O-acyltransferase 2 isoform X1

    Conserved Domains (1) summary
    cl17185
    Location:55347
    LPLAT; Lysophospholipid acyltransferases (LPLATs) of glycerophospholipid biosynthesis