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DPY19L1 dpy-19 like C-mannosyltransferase 1 [ Homo sapiens (human) ]

Gene ID: 23333, updated on 4-Jul-2021

Summary

Official Symbol
DPY19L1provided by HGNC
Official Full Name
dpy-19 like C-mannosyltransferase 1provided by HGNC
Primary source
HGNC:HGNC:22205
See related
Ensembl:ENSG00000173852 MIM:613892
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Expression
Ubiquitous expression in testis (RPKM 12.8), brain (RPKM 12.6) and 24 other tissues See more
Orthologs
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Genomic context

See DPY19L1 in Genome Data Viewer
Location:
7p14.2
Exon count:
23
Annotation release Status Assembly Chr Location
109.20210514 current GRCh38.p13 (GCF_000001405.39) 7 NC_000007.14 (34928881..35038041, complement)
105.20201022 previous assembly GRCh37.p13 (GCF_000001405.25) 7 NC_000007.13 (34968493..35077653, complement)

Chromosome 7 - NC_000007.14Genomic Context describing neighboring genes Neighboring gene NPSR1 antisense RNA 1 Neighboring gene neuropeptide S receptor 1 Neighboring gene RNA, 7SL, cytoplasmic 132, pseudogene Neighboring gene non-SMC condensin I complex subunit D2 pseudogene 1 Neighboring gene uncharacterized LOC102724723 Neighboring gene microRNA 548n Neighboring gene uncharacterized LOC105375228 Neighboring gene DPY19L2 pseudogene 1 Neighboring gene S100A11 pseudogene 2 Neighboring gene VISTA enhancer hs466 Neighboring gene T-box transcription factor 20

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

HIV-1 interactions

Protein interactions

Protein Gene Interaction Pubs
Vpr vpr HIV-1 Vpr is identified to have a physical interaction with dpy-19-like 1 (DPY19L1) in human HEK293 and/or Jurkat cell lines by using affinity tagging and purification mass spectrometry analyses PubMed

Go to the HIV-1, Human Interaction Database

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Clone Names

  • KIAA0877

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables mannosyltransferase activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Process Evidence Code Pubs
involved_in protein C-linked glycosylation via 2'-alpha-mannosyl-L-tryptophan IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Component Evidence Code Pubs
located_in integral component of membrane IEA
Inferred from Electronic Annotation
more info
 
located_in membrane HDA PubMed 
is_active_in nuclear inner membrane IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 

General protein information

Preferred Names
probable C-mannosyltransferase DPY19L1
Names
DPY-19-like protein 1
protein dpy-19 homolog 1
NP_001353602.1
NP_056098.1
XP_011513548.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001366673.1NP_001353602.1  probable C-mannosyltransferase DPY19L1 isoform 1

    Status: VALIDATED

    Source sequence(s)
    AC004711, AC004712, AC005271, AC005401
    Related
    ENSP00000490722.1, ENST00000638088.2
    Conserved Domains (1) summary
    pfam10034
    Location:102744
    Dpy19; Q-cell neuroblast polarisation
  2. NM_015283.2NP_056098.1  probable C-mannosyltransferase DPY19L1 isoform 2

    See identical proteins and their annotated locations for NP_056098.1

    Status: VALIDATED

    Source sequence(s)
    BC064476, DQ287932
    Consensus CDS
    CCDS43567.1
    UniProtKB/Swiss-Prot
    Q2PZI1
    Related
    ENSP00000308695.4, ENST00000310974.8
    Conserved Domains (1) summary
    pfam10034
    Location:29671
    Dpy19; Q-cell neuroblast polarization

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.20210514

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000007.14 Reference GRCh38.p13 Primary Assembly

    Range
    34928881..35038041 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_011515246.3XP_011513548.1  probable C-mannosyltransferase DPY19L1 isoform X2

    Conserved Domains (1) summary
    pfam10034
    Location:102715
    Dpy19; Q-cell neuroblast polarization
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