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Dpy19l3 dpy-19-like 3 (C. elegans) [ Mus musculus (house mouse) ]

Gene ID: 233115, updated on 26-Sep-2022

Summary

Official Symbol
Dpy19l3provided by MGI
Official Full Name
dpy-19-like 3 (C. elegans)provided by MGI
Primary source
MGI:MGI:2443952
See related
Ensembl:ENSMUSG00000043671 AllianceGenome:MGI:2443952
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
6030410G08; 9330164H19Rik
Summary
Predicted to enable mannosyltransferase activity. Predicted to be involved in protein C-linked glycosylation via 2'-alpha-mannosyl-L-tryptophan. Predicted to be located in membrane. Predicted to be integral component of membrane. Predicted to be active in nuclear inner membrane. Is expressed in cerebral cortex. Orthologous to human DPY19L3 (dpy-19 like C-mannosyltransferase 3). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Ubiquitous expression in whole brain E14.5 (RPKM 5.0), CNS E14 (RPKM 4.9) and 27 other tissues See more
Orthologs
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Genomic context

See Dpy19l3 in Genome Data Viewer
Location:
7; 7 B2
Exon count:
19
Annotation release Status Assembly Chr Location
109 current GRCm39 (GCF_000001635.27) 7 NC_000073.7 (35384925..35453879, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 7 NC_000073.6 (35685500..35754460, complement)

Chromosome 7 - NC_000073.7Genomic Context describing neighboring genes Neighboring gene programmed cell death 5 Neighboring gene predicted gene, 42379 Neighboring gene zinc finger protein 507 Neighboring gene RIKEN cDNA E130304I02 gene Neighboring gene predicted gene, 36234

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Targeted (1) 
  • Endonuclease-mediated (1) 

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables glycosyltransferase activity IEA
Inferred from Electronic Annotation
more info
 
enables mannosyltransferase activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables transferase activity IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
involved_in protein C-linked glycosylation via 2'-alpha-mannosyl-L-tryptophan IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Component Evidence Code Pubs
located_in membrane IEA
Inferred from Electronic Annotation
more info
 
is_active_in nuclear inner membrane IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 

General protein information

Preferred Names
probable C-mannosyltransferase DPY19L3
Names
dpy-19-like protein 3
protein dpy-19 homolog 3

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_178704.3NP_848819.2  probable C-mannosyltransferase DPY19L3

    See identical proteins and their annotated locations for NP_848819.2

    Status: VALIDATED

    Source sequence(s)
    AC166160, AK034217, AK045758
    Consensus CDS
    CCDS21155.1
    UniProtKB/Swiss-Prot
    Q71B07, Q8BZW5
    Related
    ENSMUSP00000054747.9, ENSMUST00000051377.15
    Conserved Domains (1) summary
    pfam10034
    Location:56711
    Dpy19; Q-cell neuroblast polarization

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000073.7 Reference GRCm39 C57BL/6J

    Range
    35384925..35453879 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006539906.2XP_006539969.1  probable C-mannosyltransferase DPY19L3 isoform X1

    Conserved Domains (1) summary
    pfam10034
    Location:1449
    Dpy19; Q-cell neuroblast polarisation