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Garre1 granule associated Rac and RHOG effector 1 [ Mus musculus (house mouse) ]

Gene ID: 233103, updated on 26-Sep-2022

Summary

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Official Symbol
Garre1provided by MGI
Official Full Name
granule associated Rac and RHOG effector 1provided by MGI
Primary source
MGI:MGI:1924311
See related
Ensembl:ENSMUSG00000066571 AllianceGenome:MGI:1924311
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
mKIAA0355; 4931406P16Rik
Summary
Predicted to enable CCR4-NOT complex binding activity and small GTPase binding activity. Predicted to be involved in Rac protein signal transduction. Predicted to be located in P-body. Is expressed in lung and ovary. Orthologous to human GARRE1 (granule associated Rac and RHOG effector 1). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Ubiquitous expression in lung adult (RPKM 32.6), ovary adult (RPKM 21.2) and 28 other tissues See more
Orthologs
human all
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Genomic context

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See Garre1 in Genome Data Viewer
Location:
7; 7 B1
Exon count:
18
Annotation release Status Assembly Chr Location
109 current GRCm39 (GCF_000001635.27) 7 NC_000073.7 (33936132..34012990, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 7 NC_000073.6 (34236707..34313554, complement)

Chromosome 7 - NC_000073.7Genomic Context describing neighboring genes Neighboring gene glucose-6-phosphate isomerase 1 Neighboring gene predicted gene 12762 Neighboring gene predicted gene 12758 Neighboring gene VISTA enhancer mm1379 Neighboring gene LSM14A mRNA processing body assembly factor Neighboring gene 39S ribosomal protein L27, mitochondrial pseudogene Neighboring gene predicted gene 12764

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

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Related articles in PubMed

  1. Telencephalic embryonic subtractive sequences: a unique collection of neurodevelopmental genes. Bulfone A, et al. J Neurosci, 2005 Aug 17. PMID 16107646, Free PMC Article
  2. Prediction of the coding sequences of mouse homologues of KIAA gene: III. the complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries. Okazaki N, et al. DNA Res, 2003 Aug 31. PMID 14621295
  3. Database resources of the National Center for Biotechnology Information. Wheeler DL, et al. Nucleic Acids Res, 2001 Jan 1. PMID 11125038, Free PMC Article
  4. Genome-wide expression profiling of mid-gestation placenta and embryo using a 15,000 mouse developmental cDNA microarray. Tanaka TS, et al. Proc Natl Acad Sci U S A, 2000 Aug 1. PMID 10922068, Free PMC Article
  5. Large-scale gene trapping in C57BL/6N mouse embryonic stem cells. Hansen GM, et al. Genome Res, 2008 Oct. PMID 18799693, Free PMC Article

See all (17) citations in PubMed

See citations in PubMed for homologs of this gene provided by HomoloGene

GeneRIFs: Gene References Into Functions

Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Endonuclease-mediated (1) 

General gene information

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Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables CCR4-NOT complex binding IBA
Inferred from Biological aspect of Ancestor
more info
 PubMed 
enables CCR4-NOT complex binding ISO
Inferred from Sequence Orthology
more info
  
enables small GTPase binding ISO
Inferred from Sequence Orthology
more info
  
Process Evidence Code Pubs
involved_in Rac protein signal transduction IBA
Inferred from Biological aspect of Ancestor
more info
 PubMed 
involved_in Rac protein signal transduction ISO
Inferred from Sequence Orthology
more info
  
Component Evidence Code Pubs
located_in P-body ISO
Inferred from Sequence Orthology
more info
  

General protein information

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Preferred Names
granule associated Rac and RHOG effector protein 1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001382305.1 → NP_001369234.1  granule associated Rac and RHOG effector protein 1

    Status: VALIDATED

    Source sequence(s)
    BX537302
    UniProtKB/TrEMBL
    Q8C5X1
    Related
    ENSMUSP00000103709.2, ENSMUST00000108074.8
    Conserved Domains (1) summary
    pfam15923
    Location:59 → 187
    DUF4745; Domain of unknown function (DUF4745)

  2. NM_172741.3 → NP_766329.1  granule associated Rac and RHOG effector protein 1

    See identical proteins and their annotated locations for NP_766329.1

    Status: VALIDATED

    Source sequence(s)
    BX537302
    Consensus CDS
    CCDS21139.1
    UniProtKB/TrEMBL
    Q8C5X1
    Related
    ENSMUSP00000082730.5, ENSMUST00000085592.6
    Conserved Domains (1) summary
    pfam15923
    Location:59 → 187
    DUF4745; Domain of unknown function (DUF4745)

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000073.7 Reference GRCm39 C57BL/6J

    Range
    33936132..34012990 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006539896.4 → XP_006539959.1  granule associated Rac and RHOG effector protein 1 isoform X1

    See identical proteins and their annotated locations for XP_006539959.1

    UniProtKB/TrEMBL
    Q8C5X1
    Conserved Domains (1) summary
    pfam15923
    Location:59 → 187
    DUF4745; Domain of unknown function (DUF4745)

  2. XM_030242461.1 → XP_030098321.1  granule associated Rac and RHOG effector protein 1 isoform X1

    UniProtKB/TrEMBL
    Q8C5X1
    Conserved Domains (1) summary
    pfam15923
    Location:59 → 187
    DUF4745; Domain of unknown function (DUF4745)

  3. XM_006539895.2 → XP_006539958.1  granule associated Rac and RHOG effector protein 1 isoform X1

    See identical proteins and their annotated locations for XP_006539958.1

    UniProtKB/TrEMBL
    Q8C5X1
    Related
    ENSMUSP00000145762.2, ENSMUST00000206399.2
    Conserved Domains (1) summary
    pfam15923
    Location:59 → 187
    DUF4745; Domain of unknown function (DUF4745)

  4. XM_030242458.2 → XP_030098318.1  granule associated Rac and RHOG effector protein 1 isoform X1

    UniProtKB/TrEMBL
    Q8C5X1
    Conserved Domains (1) summary
    pfam15923
    Location:59 → 187
    DUF4745; Domain of unknown function (DUF4745)

  5. XM_006539897.3 → XP_006539960.1  granule associated Rac and RHOG effector protein 1 isoform X1

    See identical proteins and their annotated locations for XP_006539960.1

    UniProtKB/TrEMBL
    Q8C5X1
    Conserved Domains (1) summary
    pfam15923
    Location:59 → 187
    DUF4745; Domain of unknown function (DUF4745)

  6. XM_030242462.1 → XP_030098322.1  granule associated Rac and RHOG effector protein 1 isoform X1

    UniProtKB/TrEMBL
    Q8C5X1
    Conserved Domains (1) summary
    pfam15923
    Location:59 → 187
    DUF4745; Domain of unknown function (DUF4745)

  7. XM_030242459.1 → XP_030098319.1  granule associated Rac and RHOG effector protein 1 isoform X1

    UniProtKB/TrEMBL
    Q8C5X1
    Conserved Domains (1) summary
    pfam15923
    Location:59 → 187
    DUF4745; Domain of unknown function (DUF4745)

  8. XM_030242460.2 → XP_030098320.1  granule associated Rac and RHOG effector protein 1 isoform X1

    UniProtKB/TrEMBL
    Q8C5X1
    Conserved Domains (1) summary
    pfam15923
    Location:59 → 187
    DUF4745; Domain of unknown function (DUF4745)

  9. XM_006539899.5 → XP_006539962.1  granule associated Rac and RHOG effector protein 1 isoform X1

    See identical proteins and their annotated locations for XP_006539962.1

    UniProtKB/TrEMBL
    Q8C5X1
    Conserved Domains (1) summary
    pfam15923
    Location:59 → 187
    DUF4745; Domain of unknown function (DUF4745)
Nucleotide Protein Strain
Heading Accession and Version

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