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Alkbh6 alkB homolog 6 [ Mus musculus (house mouse) ]

Gene ID: 233065, updated on 4-May-2024

Summary

Official Symbol
Alkbh6provided by MGI
Official Full Name
alkB homolog 6provided by MGI
Primary source
MGI:MGI:2142037
See related
Ensembl:ENSMUSG00000042831 AllianceGenome:MGI:2142037
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Abh6; C130099A02
Summary
Predicted to enable dioxygenase activity and metal ion binding activity. Predicted to be located in focal adhesion and nucleoplasm. Orthologous to human ALKBH6 (alkB homolog 6). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Ubiquitous expression in adrenal adult (RPKM 102.7), ovary adult (RPKM 80.7) and 28 other tissues See more
Orthologs
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Genomic context

See Alkbh6 in Genome Data Viewer
Location:
7 B1; 7 17.38 cM
Exon count:
7
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 7 NC_000073.7 (30008178..30013728)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 7 NC_000073.6 (30308753..30314303)

Chromosome 7 - NC_000073.7Genomic Context describing neighboring genes Neighboring gene RIKEN cDNA 1700020L13 gene Neighboring gene THAP domain containing 8, pseudogene Neighboring gene CAP-GLY domain containing linker protein 3 Neighboring gene STARR-positive B cell enhancer ABC_E3711 Neighboring gene spectrin repeat containing, nuclear envelope family member 4 Neighboring gene STARR-positive B cell enhancer ABC_E1730 Neighboring gene succinate dehydrogenase complex assembly factor 1

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Gene trapped (1) 
  • Targeted (2) 

General gene information

Markers

Gene Ontology Provided by MGI

Function Evidence Code Pubs
NOT enables 2-oxoglutarate-dependent dioxygenase activity IDA
Inferred from Direct Assay
more info
PubMed 
enables dioxygenase activity IEA
Inferred from Electronic Annotation
more info
 
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
 
enables oxidoreductase activity IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
involved_in biological_process ND
No biological Data available
more info
 
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 
located_in focal adhesion ISO
Inferred from Sequence Orthology
more info
 
located_in nucleoplasm ISO
Inferred from Sequence Orthology
more info
 
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
 

General protein information

Preferred Names
alpha-ketoglutarate-dependent dioxygenase alkB homolog 6
Names
alkB, alkylation repair homolog 6
alkylated DNA repair protein alkB homolog 6
probable alpha-ketoglutarate-dependent dioxygenase ABH6
NP_932144.2

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_198027.3NP_932144.2  alpha-ketoglutarate-dependent dioxygenase alkB homolog 6

    See identical proteins and their annotated locations for NP_932144.2

    Status: VALIDATED

    Source sequence(s)
    AC149067
    Consensus CDS
    CCDS21085.1
    UniProtKB/Swiss-Prot
    G3X994, Q8K2U2
    UniProtKB/TrEMBL
    D3Z1T0
    Related
    ENSMUSP00000051515.6, ENSMUST00000060834.12
    Conserved Domains (1) summary
    cl21496
    Location:24224
    2OG-FeII_Oxy; 2OG-Fe(II) oxygenase superfamily

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000073.7 Reference GRCm39 C57BL/6J

    Range
    30008178..30013728
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)