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Zfp382 zinc finger protein 382 [ Mus musculus (house mouse) ]

Gene ID: 233060, updated on 4-Jun-2024

Summary

Official Symbol
Zfp382provided by MGI
Official Full Name
zinc finger protein 382provided by MGI
Primary source
MGI:MGI:3588204
See related
Ensembl:ENSMUSG00000074220 AllianceGenome:MGI:3588204
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
KS1; Znf382; 4930428B01Rik; 5930415A09Rik
Summary
Predicted to enable DNA-binding transcription repressor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in negative regulation of transcription by RNA polymerase II. Predicted to be located in nucleus. Orthologous to human ZNF382 (zinc finger protein 382). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Broad expression in CNS E18 (RPKM 2.8), testis adult (RPKM 2.3) and 24 other tissues See more
Orthologs
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Genomic context

See Zfp382 in Genome Data Viewer
Location:
7; 7 B1
Exon count:
5
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 7 NC_000073.7 (29821255..29840180)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 7 NC_000073.6 (30121833..30140758)

Chromosome 7 - NC_000073.7Genomic Context describing neighboring genes Neighboring gene STARR-seq mESC enhancer starr_18504 Neighboring gene zinc finger protein 566 Neighboring gene STARR-positive B cell enhancer ABC_E869 Neighboring gene zinc finger protein 260 Neighboring gene STARR-seq mESC enhancer starr_18505 Neighboring gene STARR-seq mESC enhancer starr_18508 Neighboring gene zinc finger protein 334 pseudogene Neighboring gene STARR-seq mESC enhancer starr_18509 Neighboring gene zinc finger protein 146

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Targeted (1) 

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General protein information

Preferred Names
zinc finger protein 382
Names
KRAB/zinc finger suppressor protein 1
multiple zinc finger and krueppel-associated box protein KS1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001081007.2NP_001074476.1  zinc finger protein 382 isoform 1

    See identical proteins and their annotated locations for NP_001074476.1

    Status: VALIDATED

    Source sequence(s)
    AC164703
    Consensus CDS
    CCDS39877.1
    UniProtKB/Swiss-Prot
    B2RXC5, Q3UYY9
    Related
    ENSMUSP00000096196.4, ENSMUST00000098596.11
    Conserved Domains (6) summary
    smart00349
    Location:42102
    KRAB; krueppel associated box
    COG5048
    Location:411562
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:411431
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam00096
    Location:523543
    zf-C2H2; Zinc finger, C2H2 type
    pfam01352
    Location:4281
    KRAB; KRAB box
    pfam13465
    Location:535560
    zf-H2C2_2; Zinc-finger double domain
  2. NM_001362158.1NP_001349087.1  zinc finger protein 382 isoform 2

    Status: VALIDATED

    Source sequence(s)
    AC164703
    Conserved Domains (3) summary
    smart00349
    Location:42102
    KRAB; krueppel associated box
    COG5048
    Location:410561
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:410430
    ZF_C2H2; C2H2 Zn finger [structural motif]
  3. NM_001362159.1NP_001349088.1  zinc finger protein 382 isoform 3

    Status: VALIDATED

    Source sequence(s)
    AC164703
    Conserved Domains (3) summary
    smart00349
    Location:1272
    KRAB; krueppel associated box
    COG5048
    Location:381532
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:381401
    ZF_C2H2; C2H2 Zn finger [structural motif]

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000073.7 Reference GRCm39 C57BL/6J

    Range
    29821255..29840180
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_017322166.3XP_017177655.1  zinc finger protein 382 isoform X1

    Conserved Domains (4) summary
    smart00349
    Location:1272
    KRAB; krueppel associated box
    COG5048
    Location:380531
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:380400
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam00096
    Location:294316
    zf-C2H2; Zinc finger, C2H2 type