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Zfp790 zinc finger protein 790 [ Mus musculus (house mouse) ]

Gene ID: 233056, updated on 8-Dec-2022

Summary

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Official Symbol
Zfp790provided by MGI
Official Full Name
zinc finger protein 790provided by MGI
Primary source
MGI:MGI:1923431
See related
Ensembl:ENSMUSG00000011427 AllianceGenome:MGI:1923431
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
6330581L23Rik
Summary
Predicted to enable DNA-binding transcription repressor activity, RNA polymerase II-specific and RNA polymerase II transcription regulatory region sequence-specific DNA binding activity. Predicted to be involved in negative regulation of transcription by RNA polymerase II. Is expressed in several structures, including 1st branchial arch; early conceptus; eye; maxillary process; and oocyte. Orthologous to human ZNF790 (zinc finger protein 790). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Ubiquitous expression in CNS E18 (RPKM 2.5), CNS E14 (RPKM 2.4) and 28 other tissues See more
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Genomic context

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See Zfp790 in Genome Data Viewer
Location:
7; 7 B1
Exon count:
5
Annotation release Status Assembly Chr Location
109 current GRCm39 (GCF_000001635.27) 7 NC_000073.7 (29510862..29531467)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 7 NC_000073.6 (29811437..29832042)

Chromosome 7 - NC_000073.7Genomic Context describing neighboring genes Neighboring gene zinc finger protein 30 Neighboring gene predicted gene 6579 Neighboring gene zinc finger protein 940 Neighboring gene zinc finger protein 420

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

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Related articles in PubMed

  1. Identification and developmental analysis of genes expressed by dopaminergic neurons of the substantia nigra pars compacta. Thuret S, et al. Mol Cell Neurosci, 2004 Mar. PMID 15033168
  2. Resolution of cell fate decisions revealed by single-cell gene expression analysis from zygote to blastocyst. Guo G, et al. Dev Cell, 2010 Apr 20. PMID 20412781
  3. A systems approach reveals that the myogenesis genome network is regulated by the transcriptional repressor RP58. Yokoyama S, et al. Dev Cell, 2009 Dec. PMID 20059953, Free PMC Article
  4. Mouse brain organization revealed through direct genome-scale TF expression analysis. Gray PA, et al. Science, 2004 Dec 24. PMID 15618518
  5. Genome-wide expression profiling of mid-gestation placenta and embryo using a 15,000 mouse developmental cDNA microarray. Tanaka TS, et al. Proc Natl Acad Sci U S A, 2000 Aug 1. PMID 10922068, Free PMC Article

See all (15) citations in PubMed

See citations in PubMed for homologs of this gene provided by HomoloGene

GeneRIFs: Gene References Into Functions

Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Endonuclease-mediated (2) 

General gene information

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Homology

Clone Names

  • MGC6654

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables DNA-binding transcription repressor activity, RNA polymerase II-specific IBA
Inferred from Biological aspect of Ancestor
more info
 PubMed 
Process Evidence Code Pubs
involved_in negative regulation of transcription by RNA polymerase II IBA
Inferred from Biological aspect of Ancestor
more info
 PubMed 

General protein information

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Preferred Names
zinc finger protein 790

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001145880.1 → NP_001139352.1  zinc finger protein 790

    See identical proteins and their annotated locations for NP_001139352.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) differs in the 5' UTR compared to variant 1. Both variants 1 and 2 encode the same protein.
    Source sequence(s)
    AK018258, AK030519, BC046774, BG081821, BQ443561, CJ228115
    Consensus CDS
    CCDS52174.1
    UniProtKB/TrEMBL
    Q80ZX2
    Related
    ENSMUSP00000136932.2, ENSMUST00000178162.3
    Conserved Domains (4) summary
    smart00349
    Location:5 → 61
    KRAB; krueppel associated box
    COG5048
    Location:224 → 686
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:282 → 302
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam13465
    Location:682 → 707
    zf-H2C2_2; Zinc-finger double domain

  2. NM_146185.2 → NP_666297.2  zinc finger protein 790

    See identical proteins and their annotated locations for NP_666297.2

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) represents the longer transcript. Both variants 1 and 2 encode the same protein.
    Source sequence(s)
    AK018258, AK030519, BC046774, BG081821, CJ228115
    Consensus CDS
    CCDS52174.1
    UniProtKB/TrEMBL
    Q80ZX2
    Related
    ENSMUSP00000032796.7, ENSMUST00000032796.14
    Conserved Domains (4) summary
    smart00349
    Location:5 → 61
    KRAB; krueppel associated box
    COG5048
    Location:224 → 686
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:282 → 302
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam13465
    Location:682 → 707
    zf-H2C2_2; Zinc-finger double domain

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000073.7 Reference GRCm39 C57BL/6J

    Range
    29510862..29531467
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_011250532.3 → XP_011248834.1  zinc finger protein 790 isoform X1

    See identical proteins and their annotated locations for XP_011248834.1

    UniProtKB/TrEMBL
    Q80ZX2
    Conserved Domains (4) summary
    smart00349
    Location:5 → 61
    KRAB; krueppel associated box
    COG5048
    Location:224 → 686
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:282 → 302
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam13465
    Location:682 → 707
    zf-H2C2_2; Zinc-finger double domain

  2. XM_036152951.1 → XP_036008844.1  zinc finger protein 790 isoform X1

    UniProtKB/TrEMBL
    Q80ZX2
    Conserved Domains (4) summary
    smart00349
    Location:5 → 61
    KRAB; krueppel associated box
    COG5048
    Location:224 → 686
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:282 → 302
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam13465
    Location:682 → 707
    zf-H2C2_2; Zinc-finger double domain

  3. XM_011250533.3 → XP_011248835.1  zinc finger protein 790 isoform X1

    See identical proteins and their annotated locations for XP_011248835.1

    UniProtKB/TrEMBL
    Q80ZX2
    Conserved Domains (4) summary
    smart00349
    Location:5 → 61
    KRAB; krueppel associated box
    COG5048
    Location:224 → 686
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:282 → 302
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam13465
    Location:682 → 707
    zf-H2C2_2; Zinc-finger double domain

  4. XM_011250534.3 → XP_011248836.1  zinc finger protein 790 isoform X1

    See identical proteins and their annotated locations for XP_011248836.1

    UniProtKB/TrEMBL
    Q80ZX2
    Conserved Domains (4) summary
    smart00349
    Location:5 → 61
    KRAB; krueppel associated box
    COG5048
    Location:224 → 686
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:282 → 302
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam13465
    Location:682 → 707
    zf-H2C2_2; Zinc-finger double domain
Nucleotide Protein Strain
Heading Accession and Version

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