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Zfp574 zinc finger protein 574 [ Mus musculus (house mouse) ]

Gene ID: 232976, updated on 5-Jan-2023

Summary

Official Symbol
Zfp574provided by MGI
Official Full Name
zinc finger protein 574provided by MGI
Primary source
MGI:MGI:2442951
See related
Ensembl:ENSMUSG00000045252 AllianceGenome:MGI:2442951
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Znf574; A630056B21Rik
Summary
Predicted to enable DNA-binding transcription activator activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be active in nucleus. Is expressed in genitourinary system and limb. Orthologous to human ZNF574 (zinc finger protein 574). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Broad expression in testis adult (RPKM 59.4), ovary adult (RPKM 14.9) and 24 other tissues See more
Orthologs
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Genomic context

See Zfp574 in Genome Data Viewer
Location:
7; 7 A3
Exon count:
5
Annotation release Status Assembly Chr Location
109 current GRCm39 (GCF_000001635.27) 7 NC_000073.7 (24775099..24782917)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 7 NC_000073.6 (25075674..25083492)

Chromosome 7 - NC_000073.7Genomic Context describing neighboring genes Neighboring gene microRNA 7046 Neighboring gene Rab acceptor 1 (prenylated) Neighboring gene ATPase, Na+/K+ transporting, alpha 3 polypeptide Neighboring gene microRNA 7047 Neighboring gene glutamate receptor, ionotropic, kainate 5 (gamma 2) Neighboring gene POU domain, class 2, transcription factor 2 Neighboring gene microRNA 6537 Neighboring gene RIKEN cDNA D930028M14 gene

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables DNA binding IEA
Inferred from Electronic Annotation
more info
 
enables DNA-binding transcription activator activity, RNA polymerase II-specific IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001168506.2NP_001161978.1  zinc finger protein 574

    See identical proteins and their annotated locations for NP_001161978.1

    Status: VALIDATED

    Source sequence(s)
    AC125468, AK143997, BC059044
    Consensus CDS
    CCDS20971.1
    UniProtKB/Swiss-Prot
    Q8BKB5, Q8BY46
    Conserved Domains (2) summary
    COG5048
    Location:498852
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:500520
    ZF_C2H2; C2H2 Zn finger [structural motif]
  2. NM_175477.5NP_780686.1  zinc finger protein 574

    See identical proteins and their annotated locations for NP_780686.1

    Status: VALIDATED

    Source sequence(s)
    AC125468, AK143997, BC059044, BY087218
    Consensus CDS
    CCDS20971.1
    UniProtKB/Swiss-Prot
    Q8BKB5, Q8BY46
    Related
    ENSMUSP00000057817.10, ENSMUST00000053410.11
    Conserved Domains (2) summary
    COG5048
    Location:498852
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:500520
    ZF_C2H2; C2H2 Zn finger [structural motif]

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000073.7 Reference GRCm39 C57BL/6J

    Range
    24775099..24782917
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006539850.3XP_006539913.1  zinc finger protein 574 isoform X1

    Conserved Domains (2) summary
    COG5048
    Location:541895
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:543563
    ZF_C2H2; C2H2 Zn finger [structural motif]
  2. XM_006539852.5XP_006539915.1  zinc finger protein 574 isoform X2

    See identical proteins and their annotated locations for XP_006539915.1

    UniProtKB/Swiss-Prot
    Q8BKB5, Q8BY46
    Conserved Domains (2) summary
    COG5048
    Location:498852
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:500520
    ZF_C2H2; C2H2 Zn finger [structural motif]