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Mypop Myb-related transcription factor, partner of profilin [ Mus musculus (house mouse) ]

Gene ID: 232934, updated on 21-May-2024

Summary

Official Symbol
Mypopprovided by MGI
Official Full Name
Myb-related transcription factor, partner of profilinprovided by MGI
Primary source
MGI:MGI:2446472
See related
Ensembl:ENSMUSG00000048481 AllianceGenome:MGI:2446472
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
P42pop; Myodysa
Summary
Enables DNA-binding transcription repressor activity, RNA polymerase II-specific; RNA polymerase II cis-regulatory region sequence-specific DNA binding activity; and identical protein binding activity. Acts upstream of or within negative regulation of transcription by RNA polymerase II. Located in nucleus. Is expressed in several structures, including central nervous system; genitourinary system; liver; lung; and spleen. Orthologous to human MYPOP (Myb related transcription factor, partner of profilin). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Broad expression in adrenal adult (RPKM 11.9), testis adult (RPKM 10.6) and 24 other tissues See more
Orthologs
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Genomic context

See Mypop in Genome Data Viewer
Location:
7 A3; 7 9.45 cM
Exon count:
5
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 7 NC_000073.7 (18725230..18735691)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 7 NC_000073.6 (18991240..19001766)

Chromosome 7 - NC_000073.7Genomic Context describing neighboring genes Neighboring gene NOVA alternative splicing regulator 2 Neighboring gene predicted gene, 38952 Neighboring gene STARR-positive B cell enhancer ABC_E1080 Neighboring gene nanos C2HC-type zinc finger 2 Neighboring gene interferon regulatory factor 2 binding protein 1 Neighboring gene forkhead box A3

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Gene Ontology Provided by MGI

Component Evidence Code Pubs
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
 
located_in nucleus IDA
Inferred from Direct Assay
more info
PubMed 

General protein information

Preferred Names
myb-related transcription factor, partner of profilin
Names
Myb protein P42POP
myb-related protein p42POP
myotonic dystrophy region
partner of profilin

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001420727.1NP_001407656.1  myb-related transcription factor, partner of profilin isoform 1

    Status: VALIDATED

    Source sequence(s)
    AC170864
    UniProtKB/Swiss-Prot
    Q7TNR1, Q8CFP0, Q8R4U1
    Related
    ENSMUSP00000117357.2, ENSMUST00000131087.2
  2. NM_001420728.1NP_001407657.1  myb-related transcription factor, partner of profilin isoform 2

    Status: VALIDATED

    Source sequence(s)
    AC170864
  3. NM_001420729.1NP_001407658.1  myb-related transcription factor, partner of profilin isoform 3

    Status: VALIDATED

    Source sequence(s)
    AC170864
  4. NM_145579.4NP_663554.1  myb-related transcription factor, partner of profilin isoform 1

    See identical proteins and their annotated locations for NP_663554.1

    Status: VALIDATED

    Source sequence(s)
    AC170864
    Consensus CDS
    CCDS39792.1
    UniProtKB/Swiss-Prot
    Q7TNR1, Q8CFP0, Q8R4U1
    Related
    ENSMUSP00000058718.9, ENSMUST00000059331.9
    Conserved Domains (1) summary
    pfam13873
    Location:2096
    Myb_DNA-bind_5; Myb/SANT-like DNA-binding domain

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000073.7 Reference GRCm39 C57BL/6J

    Range
    18725230..18735691
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)