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Ccdc106 coiled-coil domain containing 106 [ Mus musculus (house mouse) ]

Gene ID: 232821, updated on 17-Aug-2024

Summary

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Official Symbol
Ccdc106provided by MGI
Official Full Name
coiled-coil domain containing 106provided by MGI
Primary source
MGI:MGI:2385900
See related
Ensembl:ENSMUSG00000035228 AllianceGenome:MGI:2385900
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Summary
Predicted to be located in cytosol. Predicted to be active in nucleoplasm. Orthologous to human CCDC106 (coiled-coil domain containing 106). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Biased expression in CNS E18 (RPKM 12.7), frontal lobe adult (RPKM 10.3) and 14 other tissues See more
Orthologs
human all
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Genomic context

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Location:
7 A1; 7 2.92 cM
Exon count:
11
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 7 NC_000073.7 (5056870..5063784)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 7 NC_000073.6 (5053842..5060785)

Chromosome 7 - NC_000073.7Genomic Context describing neighboring genes Neighboring gene STARR-positive B cell enhancer ABC_E3696 Neighboring gene zinc finger protein 784 Neighboring gene zinc finger protein 580 Neighboring gene STARR-positive B cell enhancer ABC_E4890 Neighboring gene predicted gene 15510 Neighboring gene STARR-positive B cell enhancer ABC_E3697 Neighboring gene STARR-positive B cell enhancer ABC_E9020 Neighboring gene STARR-positive B cell enhancer ABC_E4891 Neighboring gene U2 small nuclear ribonucleoprotein auxiliary factor (U2AF) 2 Neighboring gene epsin 1

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Mouse ENCODE transcriptome data Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

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Related articles in PubMed

  1. Ezh2, the histone methyltransferase of PRC2, regulates the balance between self-renewal and differentiation in the cerebral cortex. Pereira JD, et al. Proc Natl Acad Sci U S A, 2010 Sep 7. PMID 20798045, Free PMC Article
  2. A conditional knockout resource for the genome-wide study of mouse gene function. Skarnes WC, et al. Nature, 2011 Jun 15. PMID 21677750, Free PMC Article
  3. Normalization and subtraction: two approaches to facilitate gene discovery. Bonaldo MF, et al. Genome Res, 1996 Sep. PMID 8889548
  4. Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention. Zambrowicz BP, et al. Proc Natl Acad Sci U S A, 2003 Nov 25. PMID 14610273, Free PMC Article
  5. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). Gerhard DS, et al. Genome Res, 2004 Oct. PMID 15489334, Free PMC Article

See all (14) citations in PubMed

GeneRIFs: Gene References Into Functions

Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Targeted (1) 

General gene information

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Homology

Clone Names

  • MGC27915

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
  
Process Evidence Code Pubs
involved_in biological_process ND
No biological Data available
more info
  
Component Evidence Code Pubs
located_in cytosol ISO
Inferred from Sequence Orthology
more info
  
is_active_in nucleoplasm IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in nucleoplasm ISO
Inferred from Sequence Orthology
more info
  
located_in nucleus IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
coiled-coil domain-containing protein 106

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001290429.2 → NP_001277358.1  coiled-coil domain-containing protein 106 isoform a

    See identical proteins and their annotated locations for NP_001277358.1

    Status: VALIDATED

    Source sequence(s)
    AC162893
    Consensus CDS
    CCDS80660.1
    UniProtKB/TrEMBL
    E9QPN6
    Conserved Domains (1) summary
    pfam15794
    Location:117 → 336
    CCDC106; Coiled-coil domain-containing protein 106

  2. NM_001290432.2 → NP_001277361.1  coiled-coil domain-containing protein 106 isoform b

    See identical proteins and their annotated locations for NP_001277361.1

    Status: VALIDATED

    Source sequence(s)
    AC162893
    Consensus CDS
    CCDS20757.1
    UniProtKB/Swiss-Prot
    Q3ULM0, Q8K5E2, Q8VEI0
    Conserved Domains (1) summary
    pfam15794
    Location:57 → 273
    CCDC106; Coiled-coil domain-containing protein 106

  3. NM_001420706.1 → NP_001407635.1  coiled-coil domain-containing protein 106 isoform a

    Status: VALIDATED

    Source sequence(s)
    AC162893
    UniProtKB/TrEMBL
    E9QPN6

  4. NM_001420707.1 → NP_001407636.1  coiled-coil domain-containing protein 106 isoform a

    Status: VALIDATED

    Source sequence(s)
    AC162893
    UniProtKB/TrEMBL
    E9QPN6
    Related
    ENSMUSP00000104211.2, ENSMUST00000108571.9

  5. NM_001420708.1 → NP_001407637.1  coiled-coil domain-containing protein 106 isoform c

    Status: VALIDATED

    Source sequence(s)
    AC162893

  6. NM_001420709.1 → NP_001407638.1  coiled-coil domain-containing protein 106 isoform b

    Status: VALIDATED

    Source sequence(s)
    AC162893
    UniProtKB/Swiss-Prot
    Q3ULM0, Q8K5E2, Q8VEI0

  7. NM_001420710.1 → NP_001407639.1  coiled-coil domain-containing protein 106 isoform b

    Status: VALIDATED

    Source sequence(s)
    AC162893
    UniProtKB/Swiss-Prot
    Q3ULM0, Q8K5E2, Q8VEI0

  8. NM_001420711.1 → NP_001407640.1  coiled-coil domain-containing protein 106 isoform b

    Status: VALIDATED

    Source sequence(s)
    AC162893
    UniProtKB/Swiss-Prot
    Q3ULM0, Q8K5E2, Q8VEI0

  9. NM_001420712.1 → NP_001407641.1  coiled-coil domain-containing protein 106 isoform b

    Status: VALIDATED

    Source sequence(s)
    AC162893
    UniProtKB/Swiss-Prot
    Q3ULM0, Q8K5E2, Q8VEI0

  10. NM_001420713.1 → NP_001407642.1  coiled-coil domain-containing protein 106 isoform b

    Status: VALIDATED

    Source sequence(s)
    AC162893
    UniProtKB/Swiss-Prot
    Q3ULM0, Q8K5E2, Q8VEI0

  11. NM_001420714.1 → NP_001407643.1  coiled-coil domain-containing protein 106 isoform b

    Status: VALIDATED

    Source sequence(s)
    AC162893
    UniProtKB/Swiss-Prot
    Q3ULM0, Q8K5E2, Q8VEI0

  12. NM_001420715.1 → NP_001407644.1  coiled-coil domain-containing protein 106 isoform b

    Status: VALIDATED

    Source sequence(s)
    AC162893
    UniProtKB/Swiss-Prot
    Q3ULM0, Q8K5E2, Q8VEI0

  13. NM_001420716.1 → NP_001407645.1  coiled-coil domain-containing protein 106 isoform b

    Status: VALIDATED

    Source sequence(s)
    AC162893
    UniProtKB/Swiss-Prot
    Q3ULM0, Q8K5E2, Q8VEI0

  14. NM_001420717.1 → NP_001407646.1  coiled-coil domain-containing protein 106 isoform d

    Status: VALIDATED

    Source sequence(s)
    AC162893

  15. NM_001420718.1 → NP_001407647.1  coiled-coil domain-containing protein 106 isoform e

    Status: VALIDATED

    Source sequence(s)
    AC162893
    Related
    ENSMUSP00000146775.2, ENSMUST00000207974.2

  16. NM_146178.3 → NP_666290.2  coiled-coil domain-containing protein 106 isoform b

    See identical proteins and their annotated locations for NP_666290.2

    Status: VALIDATED

    Source sequence(s)
    AC162893
    Consensus CDS
    CCDS20757.1
    UniProtKB/Swiss-Prot
    Q3ULM0, Q8K5E2, Q8VEI0
    Related
    ENSMUSP00000041033.6, ENSMUST00000045543.8
    Conserved Domains (1) summary
    pfam15794
    Location:57 → 273
    CCDC106; Coiled-coil domain-containing protein 106

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000073.7 Reference GRCm39 C57BL/6J

    Range
    5056870..5063784
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q3ULM0.1 GenPept UniProtKB/Swiss-Prot:Q3ULM0

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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