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PPIP5K2 diphosphoinositol pentakisphosphate kinase 2 [ Homo sapiens (human) ]

Gene ID: 23262, updated on 6-Jul-2026
Official Symbol
PPIP5K2provided by HGNC
Official Full Name
diphosphoinositol pentakisphosphate kinase 2provided by HGNC
Primary source
HGNC:HGNC:29035
See related
Ensembl:ENSG00000145725 MIM:611648; AllianceGenome:HGNC:29035
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
VIP2; IP7K2; CFAP160; DFNB100; HISPPD1
Summary
This gene encodes a member of the histidine acid phosphatase family of proteins. Despite containing a histidine acid phosphatase domain, the encoded protein functions as an inositol pyrophosphate kinase, and is thought to lack phosphatase activity. This kinase activity is the mechanism by which the encoded protein synthesizes high-energy inositol pyrophosphates, which act as signaling molecules that regulate cellular homeostasis and other processes. This gene may be associated with autism spectrum disorder in human patients. [provided by RefSeq, Sep 2016]
Expression
Ubiquitous expression in bone marrow (RPKM 8.5), colon (RPKM 7.8) and 25 other tissues See more
Orthologs
all
Try the new Gene page
Try the new Transcripts and proteins table
See PPIP5K2 in Genome Data Viewer
Location:
5q21.1
Exon count:
34
Annotation release Status Assembly Chr Location
RS_2025_08 current GRCh38.p14 (GCF_000001405.40) 5 NC_000005.10 (103120301..103212799)
RS_2025_08 current T2T-CHM13v2.0 (GCF_009914755.1) 5 NC_060929.1 (103628403..103720883)
RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) 5 NC_000005.9 (102456005..102548500)

Chromosome 5 - NC_000005.10Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC105379105 Neighboring gene gypsy retrotransposon integrase 1 Neighboring gene NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr5:102454978-102455479 Neighboring gene NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr5:102455480-102455980 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 22858 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 22859 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr5:102477431-102477932 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 22860 Neighboring gene uncharacterized LOC124901037 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 16210 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 16211 Neighboring gene macrophage immunometabolism regulator

Go to nucleotide: Graphics FASTA GenBank

  • Project title: Tissue-specific circular RNA induction during human fetal development
  • Description: 35 human fetal samples from 6 tissues (3 - 7 replicates per tissue) collected between 10 and 20 weeks gestational time were sequenced using Illumina TruSeq Stranded Total RNA
  • BioProject: PRJNA270632
  • Publication: PMID 26076956
  • Analysis date: Mon Apr 2 22:54:59 2018

Related articles in PubMed

  1. Dynamics of Substrate Processing by PPIP5K2, a Versatile Catalytic Machine. An Y, et al. Structure, 2019 Jun 4. PMID 30956131, Free PMC Article
  2. The kinetic properties of a human PPIP5K reveal that its kinase activities are protected against the consequences of a deteriorating cellular bioenergetic environment. Weaver JD, et al. Biosci Rep, 2013 Feb 5. PMID 23240582, Free PMC Article
  3. Identification of a functional nuclear translocation sequence in hPPIP5K2. Yong ST, et al. BMC Cell Biol, 2015 Jun 18. PMID 26084399, Free PMC Article
  4. PPIP5K2 promotes colorectal carcinoma pathogenesis through facilitating DNA homologous recombination repair. Cao CH, et al. Oncogene, 2021 Dec. PMID 34645979
  5. The Significance of the Bifunctional Kinase/Phosphatase Activities of Diphosphoinositol Pentakisphosphate Kinases (PPIP5Ks) for Coupling Inositol Pyrophosphate Cell Signaling to Cellular Phosphate Homeostasis. Gu C, et al. J Biol Chem, 2017 Mar 17. PMID 28126903, Free PMC Article

See all (48) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. PPIP5K2 promotes colorectal carcinoma pathogenesis through facilitating DNA homologous recombination repair.
    Title: PPIP5K2 promotes colorectal carcinoma pathogenesis through facilitating DNA homologous recombination repair.
  2. PPIP5K2 and PCSK1 are Candidate Genetic Contributors to Familial Keratoconus.
    Title: PPIP5K2 and PCSK1 are Candidate Genetic Contributors to Familial Keratoconus.
  3. Data suggest that the enzyme-substrate forces are predictive of the various diphosphoinositol pentakisphosphate kinase 2 (PPIP5K2) catalytic activities.
    Title: Dynamics of Substrate Processing by PPIP5K2, a Versatile Catalytic Machine.
  4. demonstration that PPIP5K2 has a role in hearing in humans indicates that PP-IP signaling is important to hair cell maintenance and function within inner ear
    Title: Mutations in Diphosphoinositol-Pentakisphosphate Kinase PPIP5K2 are associated with hearing loss in human and mouse.
  5. This study characterized kinetic properties of the bifunctional inositol pyrophosphate 5-diphosphoinositol 1,2,3,4,6-pentakisphosphatekinase/inositol pyrophosphate, 1,5-bisdiphosphoinositol 2,3,4,6-tetrakisphosphate phosphatase activities of full-length diphosphoinositol pentakisphosphate kinase 1 and 2.
    Title: The Significance of the Bifunctional Kinase/Phosphatase Activities of Diphosphoinositol Pentakisphosphate Kinases (PPIP5Ks) for Coupling Inositol Pyrophosphate Cell Signaling to Cellular Phosphate Homeostasis.
  6. SEZ6L, HISPPD1, FEZF1, SAMD11 gene variants may be associated with autism spectrum disorder.
    Title: Whole exome sequencing in extended families with autism spectrum disorder implicates four candidate genes.
  7. The degree of nuclear localization of hPPIP5K2 was increased when S1006 was rendered non-phosphorylatable by its mutation to Ala.
    Title: Identification of a functional nuclear translocation sequence in hPPIP5K2.
  8. the specificity constants for PPIP5K2 revise upwards by one-to-two orders of magnitude the inherent catalytic activities of this enzyme, and we show its equilibrium point favours 80-90% depletion of InsP/-InsP.
    Title: The kinetic properties of a human PPIP5K reveal that its kinase activities are protected against the consequences of a deteriorating cellular bioenergetic environment.
  9. describe the PPIP5K2's conformational dynamics, its unprecedented topological presentation of nucleotide and inositol phosphate, and the charge balance that facilitates partly associative in-line phosphoryl transfer
    Title: Structural basis for an inositol pyrophosphate kinase surmounting phosphate crowding.
  10. Clinical trial of gene-disease association and gene-environment interaction. (HuGE Navigator)
    Title: Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.
Submit: New GeneRIF Correction

Find tests for this gene in the NIH Genetic Testing Registry (GTR)

Review eQTL and phenotype association data in this region using PheGenI

Associated conditions

Description Tests
Hearing loss, autosomal recessive 100
MedGen: C5193087 OMIM: 618422 GeneReviews: Not available
Compare labs

See variants in ClinVar

See studies and variants in dbVar

See Variation Viewer (GRCh37.p13)

Products Interactant Other Gene Complex Source Pubs Description

Markers

Homology

Clone Names

  • FLJ21506, FLJ23463, KIAA0433

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables 5-diphosphoinositol pentakisphosphate 1-kinase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables 5-diphosphoinositol pentakisphosphate 1-kinase activity IDA
Inferred from Direct Assay
more info
 PubMed 
enables 5-diphosphoinositol pentakisphosphate 1-kinase activity IEA
Inferred from Electronic Annotation
more info
  
enables 5-diphosphoinositol pentakisphosphate 1-kinase activity ISS
Inferred from Sequence or Structural Similarity
more info
  
enables ATP binding IDA
Inferred from Direct Assay
more info
 PubMed 
enables diphosphoinositol pentakisphosphate kinase activity IEA
Inferred from Electronic Annotation
more info
  
enables diphosphoinositol pentakisphosphate kinase activity TAS
Traceable Author Statement
more info
  
enables inositol hexakisphosphate 1-kinase activity EXP
Inferred from Experiment
more info
 PubMed 
enables inositol hexakisphosphate 1-kinase activity IEA
Inferred from Electronic Annotation
more info
  
enables inositol hexakisphosphate 5-kinase activity ISS
Inferred from Sequence or Structural Similarity
more info
  
enables inositol hexakisphosphate kinase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables inositol hexakisphosphate kinase activity IDA
Inferred from Direct Assay
more info
 PubMed 
enables inositol hexakisphosphate kinase activity IEA
Inferred from Electronic Annotation
more info
  
enables inositol hexakisphosphate kinase activity TAS
Traceable Author Statement
more info
  
enables inositol-1,3,4,5,6-pentakisphosphate kinase activity ISS
Inferred from Sequence or Structural Similarity
more info
  
enables protein binding IPI
Inferred from Physical Interaction
more info
 PubMed 
Process Evidence Code Pubs
involved_in inositol metabolic process ISS
Inferred from Sequence or Structural Similarity
more info
  
involved_in inositol phosphate biosynthetic process IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in inositol phosphate metabolic process IEA
Inferred from Electronic Annotation
more info
  
involved_in inositol phosphate metabolic process TAS
Traceable Author Statement
more info
  
Component Evidence Code Pubs
is_active_in cytosol IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in cytosol IDA
Inferred from Direct Assay
more info
 PubMed 
located_in cytosol IEA
Inferred from Electronic Annotation
more info
  
located_in cytosol ISS
Inferred from Sequence or Structural Similarity
more info
  
located_in cytosol TAS
Traceable Author Statement
more info
  
Preferred Names
inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase 2
Names
VIP1 homolog 2
deafness, autosomal recessive 100
histidine acid phosphatase domain-containing protein 1
inositol heptaphosphate kinase 2
insP6 and PP-IP5 kinase 2
NP_001263206.1
NP_001268400.1
NP_001332800.1
NP_001332801.1
NP_001332802.1
NP_001332803.1
NP_001332804.1
NP_001332805.1
NP_001332806.1
NP_001332807.1
NP_056031.2
XP_005277591.1
XP_005277592.1
XP_005277593.1
XP_005277596.1
XP_005277598.1
XP_006714639.1
XP_006714640.1
XP_011541592.1
XP_016864762.1
XP_016864763.1
XP_047272962.1
XP_047272963.1
XP_047272964.1
XP_047272965.1
XP_047272966.1
XP_047272967.1
XP_047272968.1
XP_047272969.1
XP_047272970.1
XP_054208157.1
XP_054208158.1
XP_054208159.1
XP_054208160.1
XP_054208161.1
XP_054208162.1
XP_054208163.1
XP_054208164.1
XP_054208165.1
XP_054208166.1
XP_054208167.1
XP_054208168.1
XP_054208169.1
XP_054208170.1
XP_054208171.1
XP_054208172.1
XP_054208173.1
XP_054208174.1
XP_054208175.1

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

Genomic

  1. NG_051568.2 RefSeqGene

    Range
    5002..97500
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001276277.3 → NP_001263206.1  inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase 2 isoform 1

    See identical proteins and their annotated locations for NP_001263206.1

    Status: REVIEWED

    Description
    Transcript Variant: This variant (1) lacks two in-frame exons in the coding region, compared to variant 4. The resulting isoform (1) lacks two internal segments, compared to isoform (3).
    Source sequence(s)
    AB007893, AC011362, AK025159, DB298507
    Consensus CDS
    CCDS64212.1
    UniProtKB/Swiss-Prot
    A1NI53, A6NGS8, O43314, Q8TB50
    UniProtKB/TrEMBL
    B4DGV1
    Related
    ENSP00000351126.3, ENST00000358359.8
    Conserved Domains (2) summary
    COG0189
    Location:48 → 337
    RimK; Glutathione synthase/RimK-type ligase, ATP-grasp superfamily [Coenzyme transport and metabolism, Translation, ribosomal structure and biogenesis]
    pfam00328
    Location:379 → 894
    His_Phos_2; Histidine phosphatase superfamily (branch 2)

  2. NM_001281471.3 → NP_001268400.1  inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase 2 isoform 3

    Status: REVIEWED

    Description
    Transcript Variant: This variant (4) represents the longest transcript and encodes the longest isoform (3).
    Source sequence(s)
    AC011362, AK025159, AK294787, BC024591, DB298507, DC404725
    Consensus CDS
    CCDS75283.1
    UniProtKB/TrEMBL
    A0A087WZV0, B4DGV1
    Related
    ENSP00000482907.1, ENST00000613674.4
    Conserved Domains (2) summary
    COG0189
    Location:48 → 337
    RimK; Glutathione synthase/RimK-type ligase, ATP-grasp superfamily [Coenzyme transport and metabolism, Translation, ribosomal structure and biogenesis]
    pfam00328
    Location:379 → 909
    His_Phos_2; Histidine phosphatase superfamily (branch 2)

  3. NM_001345871.2 → NP_001332800.1  inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase 2 isoform 4

    Status: REVIEWED

    Source sequence(s)
    AC008447, AC011362
    Consensus CDS
    CCDS93758.1
    UniProtKB/TrEMBL
    A0A8V8TMN4, A0ACI8S7S3
    Related
    ENSP00000513912.1, ENST00000698750.1

  4. NM_001345872.2 → NP_001332801.1  inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase 2 isoform 5

    Status: REVIEWED

    Source sequence(s)
    AC008447, AC011362
    UniProtKB/TrEMBL
    A0ACI8TG60

  5. NM_001345873.2 → NP_001332802.1  inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase 2 isoform 6

    Status: REVIEWED

    Source sequence(s)
    AC008447, AC011362
    UniProtKB/TrEMBL
    A0ACI8V394, B4DGV1
    Related
    ENSP00000630578.1, ENST00000960519.1

  6. NM_001345874.2 → NP_001332803.1  inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase 2 isoform 7

    Status: REVIEWED

    Source sequence(s)
    AC008447, AC011362
    UniProtKB/TrEMBL
    A0ACI8RE51, A0ACI8S7S3
    Related
    ENSP00000551548.1, ENST00000881489.1

  7. NM_001345875.2 → NP_001332804.1  inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase 2 isoform 8

    Status: REVIEWED

    Source sequence(s)
    AC008447, AC011362
    UniProtKB/TrEMBL
    A0ACI8S7S3
    Related
    ENSP00000551555.1, ENST00000881496.1

  8. NM_001345876.2 → NP_001332805.1  inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase 2 isoform 9

    Status: REVIEWED

    Source sequence(s)
    AC008447, AC011362
    UniProtKB/TrEMBL
    A0ACI8QR40, A0ACI8S4B5
    Related
    ENSP00000551549.1, ENST00000881490.1

  9. NM_001345877.2 → NP_001332806.1  inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase 2 isoform 10

    Status: REVIEWED

    Source sequence(s)
    AC008447, AC011362
    UniProtKB/TrEMBL
    A0ACI8TG60

  10. NM_001345878.2 → NP_001332807.1  inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase 2 isoform 11

    Status: REVIEWED

    Source sequence(s)
    AC008447, AC011362
    UniProtKB/TrEMBL
    A0ACI8QR40, A0ACI8RC65
    Related
    ENSP00000551550.1, ENST00000881491.1

  11. NM_015216.5 → NP_056031.2  inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase 2 isoform 2

    See identical proteins and their annotated locations for NP_056031.2

    Status: REVIEWED

    Description
    Transcript Variant: This variant (2) lacks three internal exons in the coding region, but maintains the reading frame, compared to variant 4. The resulting isoform (2) lacks two internal segments, compared to isoform 3.
    Source sequence(s)
    AC008447, AC011362
    Consensus CDS
    CCDS34207.1
    UniProtKB/TrEMBL
    B4DGV1
    Related
    ENSP00000313070.8, ENST00000321521.13
    Conserved Domains (2) summary
    pfam00328
    Location:379 → 894
    His_Phos_2; Histidine phosphatase superfamily (branch 2)
    cl27318
    Location:48 → 337
    RimK; Glutathione synthase/RimK-type ligase, ATP-grasp superfamily [Coenzyme transport and metabolism, Translation, ribosomal structure and biogenesis]

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2025_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000005.10 Reference GRCh38.p14 Primary Assembly

    Range
    103120301..103212799
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_005277534.3 → XP_005277591.1  inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase 2 isoform X1

    UniProtKB/TrEMBL
    B4DGV1
    Conserved Domains (2) summary
    COG0189
    Location:48 → 337
    RimK; Glutathione synthase/RimK-type ligase, ATP-grasp superfamily [Coenzyme transport and metabolism, Translation, ribosomal structure and biogenesis]
    pfam00328
    Location:379 → 909
    His_Phos_2; Histidine phosphatase superfamily (branch 2)

  2. XM_005277536.3 → XP_005277593.1  inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase 2 isoform X3

    UniProtKB/TrEMBL
    A0ACI8TG45, B4DGV1
    Related
    ENSP00000597989.1, ENST00000927930.1
    Conserved Domains (2) summary
    COG0189
    Location:48 → 337
    RimK; Glutathione synthase/RimK-type ligase, ATP-grasp superfamily [Coenzyme transport and metabolism, Translation, ribosomal structure and biogenesis]
    pfam00328
    Location:379 → 909
    His_Phos_2; Histidine phosphatase superfamily (branch 2)

  3. XM_006714576.3 → XP_006714639.1  inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase 2 isoform X5

    UniProtKB/TrEMBL
    A0ACI8TG60
    Conserved Domains (2) summary
    COG0189
    Location:48 → 337
    RimK; Glutathione synthase/RimK-type ligase, ATP-grasp superfamily [Coenzyme transport and metabolism, Translation, ribosomal structure and biogenesis]
    pfam00328
    Location:379 → 909
    His_Phos_2; Histidine phosphatase superfamily (branch 2)

  4. XM_005277539.3 → XP_005277596.1  inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase 2 isoform X8

    UniProtKB/TrEMBL
    A0ACI8TG60
    Conserved Domains (2) summary
    COG0189
    Location:48 → 337
    RimK; Glutathione synthase/RimK-type ligase, ATP-grasp superfamily [Coenzyme transport and metabolism, Translation, ribosomal structure and biogenesis]
    pfam00328
    Location:379 → 909
    His_Phos_2; Histidine phosphatase superfamily (branch 2)

  5. XM_047417011.1 → XP_047272967.1  inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase 2 isoform X11

    UniProtKB/TrEMBL
    A0ACI8Q0T6, A0ACI8S7S3
    Related
    ENSP00000551558.1, ENST00000881499.1

  6. XM_006714577.3 → XP_006714640.1  inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase 2 isoform X14

    UniProtKB/TrEMBL
    A0ACI8TG60, A0ACI8V369
    Related
    ENSP00000630577.1, ENST00000960518.1
    Conserved Domains (2) summary
    COG0189
    Location:48 → 337
    RimK; Glutathione synthase/RimK-type ligase, ATP-grasp superfamily [Coenzyme transport and metabolism, Translation, ribosomal structure and biogenesis]
    pfam00328
    Location:379 → 909
    His_Phos_2; Histidine phosphatase superfamily (branch 2)

  7. XM_005277541.3 → XP_005277598.1  inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase 2 isoform X17

    UniProtKB/TrEMBL
    A0ACI8QGE3, A0ACI8TG60
    Related
    ENSP00000551551.1, ENST00000881492.1
    Conserved Domains (2) summary
    COG0189
    Location:48 → 337
    RimK; Glutathione synthase/RimK-type ligase, ATP-grasp superfamily [Coenzyme transport and metabolism, Translation, ribosomal structure and biogenesis]
    pfam00328
    Location:379 → 909
    His_Phos_2; Histidine phosphatase superfamily (branch 2)

  8. XM_047417007.1 → XP_047272963.1  inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase 2 isoform X6

    UniProtKB/TrEMBL
    A0ACI8TG60

  9. XM_017009274.3 → XP_016864763.1  inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase 2 isoform X15

    UniProtKB/TrEMBL
    A0ACI8R0G3, A0ACI8TG60
    Related
    ENSP00000551553.1, ENST00000881494.1

  10. XM_005277535.3 → XP_005277592.1  inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase 2 isoform X2

    UniProtKB/TrEMBL
    B4DGV1
    Conserved Domains (2) summary
    COG0189
    Location:48 → 337
    RimK; Glutathione synthase/RimK-type ligase, ATP-grasp superfamily [Coenzyme transport and metabolism, Translation, ribosomal structure and biogenesis]
    pfam00328
    Location:379 → 908
    His_Phos_2; Histidine phosphatase superfamily (branch 2)

  11. XM_047417009.1 → XP_047272965.1  inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase 2 isoform X9

    UniProtKB/TrEMBL
    A0ACI8TG60

  12. XM_047417008.1 → XP_047272964.1  inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase 2 isoform X7

    UniProtKB/TrEMBL
    A0ACI8TG60

  13. XM_047417012.1 → XP_047272968.1  inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase 2 isoform X12

    UniProtKB/TrEMBL
    A0ACI8S7S3

  14. XM_047417014.1 → XP_047272970.1  inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase 2 isoform X18

    UniProtKB/TrEMBL
    A0ACI8Q0C1, A0ACI8TG60
    Related
    ENSP00000551554.1, ENST00000881495.1

  15. XM_047417006.1 → XP_047272962.1  inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase 2 isoform X4

    UniProtKB/TrEMBL
    B4DGV1

  16. XM_047417010.1 → XP_047272966.1  inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase 2 isoform X10

    UniProtKB/TrEMBL
    A0ACI8S7S3

  17. XM_017009273.3 → XP_016864762.1  inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase 2 isoform X13

    UniProtKB/TrEMBL
    A0ACI8Q5G2, A0ACI8S7S3
    Related
    ENSP00000551557.1, ENST00000881498.1

  18. XM_047417013.1 → XP_047272969.1  inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase 2 isoform X16

    UniProtKB/TrEMBL
    A0ACI8RIS8, A0ACI8TG60
    Related
    ENSP00000551552.1, ENST00000881493.1

  19. XM_011543290.4 → XP_011541592.1  inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase 2 isoform X19

    UniProtKB/TrEMBL
    A0ACI8S7S3
    Conserved Domains (2) summary
    COG0189
    Location:48 → 337
    RimK; Glutathione synthase/RimK-type ligase, ATP-grasp superfamily [Coenzyme transport and metabolism, Translation, ribosomal structure and biogenesis]
    pfam00328
    Location:379 → 909
    His_Phos_2; Histidine phosphatase superfamily (branch 2)

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060929.1 Alternate T2T-CHM13v2.0

    Range
    103628403..103720883
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_054352182.1 → XP_054208157.1  inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase 2 isoform X1

    UniProtKB/TrEMBL
    B4DGV1

  2. XM_054352184.1 → XP_054208159.1  inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase 2 isoform X3

    UniProtKB/TrEMBL
    A0ACI8TG45, B4DGV1

  3. XM_054352186.1 → XP_054208161.1  inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase 2 isoform X5

    UniProtKB/TrEMBL
    A0ACI8TG60

  4. XM_054352189.1 → XP_054208164.1  inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase 2 isoform X8

    UniProtKB/TrEMBL
    A0ACI8TG60

  5. XM_054352192.1 → XP_054208167.1  inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase 2 isoform X11

    UniProtKB/TrEMBL
    A0ACI8Q0T6, A0ACI8S7S3

  6. XM_054352195.1 → XP_054208170.1  inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase 2 isoform X14

    UniProtKB/TrEMBL
    A0ACI8TG60, A0ACI8V369

  7. XM_054352198.1 → XP_054208173.1  inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase 2 isoform X17

    UniProtKB/TrEMBL
    A0ACI8QGE3, A0ACI8TG60

  8. XM_054352187.1 → XP_054208162.1  inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase 2 isoform X6

    UniProtKB/TrEMBL
    A0ACI8TG60

  9. XM_054352196.1 → XP_054208171.1  inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase 2 isoform X15

    UniProtKB/TrEMBL
    A0ACI8R0G3, A0ACI8TG60

  10. XM_054352183.1 → XP_054208158.1  inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase 2 isoform X2

    UniProtKB/TrEMBL
    B4DGV1

  11. XM_054352190.1 → XP_054208165.1  inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase 2 isoform X9

    UniProtKB/TrEMBL
    A0ACI8TG60

  12. XM_054352188.1 → XP_054208163.1  inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase 2 isoform X7

    UniProtKB/TrEMBL
    A0ACI8TG60

  13. XM_054352193.1 → XP_054208168.1  inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase 2 isoform X12

    UniProtKB/TrEMBL
    A0ACI8S7S3

  14. XM_054352199.1 → XP_054208174.1  inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase 2 isoform X18

    UniProtKB/TrEMBL
    A0ACI8Q0C1, A0ACI8TG60

  15. XM_054352185.1 → XP_054208160.1  inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase 2 isoform X4

    UniProtKB/TrEMBL
    B4DGV1

  16. XM_054352191.1 → XP_054208166.1  inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase 2 isoform X10

    UniProtKB/TrEMBL
    A0ACI8S7S3

  17. XM_054352194.1 → XP_054208169.1  inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase 2 isoform X13

    UniProtKB/TrEMBL
    A0ACI8Q5G2, A0ACI8S7S3

  18. XM_054352197.1 → XP_054208172.1  inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase 2 isoform X16

    UniProtKB/TrEMBL
    A0ACI8RIS8, A0ACI8TG60

  19. XM_054352200.1 → XP_054208175.1  inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase 2 isoform X19

    UniProtKB/TrEMBL
    A0ACI8S7S3
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
O43314.3 GenPept UniProtKB/Swiss-Prot:O43314

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