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MINAR1 membrane integral NOTCH2 associated receptor 1 [ Homo sapiens (human) ]

Gene ID: 23251, updated on 7-Jun-2020

Summary

Official Symbol
MINAR1provided by HGNC
Official Full Name
membrane integral NOTCH2 associated receptor 1provided by HGNC
Primary source
HGNC:HGNC:29172
See related
Ensembl:ENSG00000169330 MIM:618054
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
UBTOR; KIAA1024
Expression
Biased expression in adrenal (RPKM 4.7), salivary gland (RPKM 0.6) and 1 other tissue See more
Orthologs

Genomic context

See MINAR1 in Genome Data Viewer
Location:
15q25.1
Exon count:
11
Annotation release Status Assembly Chr Location
109.20200522 current GRCh38.p13 (GCF_000001405.39) 15 NC_000015.10 (79411557..79472304)
105 previous assembly GRCh37.p13 (GCF_000001405.25) 15 NC_000015.9 (79724858..79764642)

Chromosome 15 - NC_000015.10Genomic Context describing neighboring genes Neighboring gene ANKRD34C antisense RNA 1 Neighboring gene heterogeneous nuclear ribonucleoprotein C pseudogene 3 Neighboring gene ankyrin repeat domain 34C Neighboring gene transmembrane p24 trafficking protein 3 Neighboring gene uncharacterized LOC105370918 Neighboring gene uncharacterized LOC105370919 Neighboring gene TFDP1 pseudogene 3

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Gene Ontology Provided by GOA

Function Evidence Code Pubs
protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
Process Evidence Code Pubs
angiogenesis IEA
Inferred from Electronic Annotation
more info
 
negative regulation of TOR signaling IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
negative regulation of TOR signaling IMP
Inferred from Mutant Phenotype
more info
PubMed 
negative regulation of angiogenesis IMP
Inferred from Mutant Phenotype
more info
PubMed 
negative regulation of cell growth IMP
Inferred from Mutant Phenotype
more info
PubMed 
negative regulation of cell proliferation IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
negative regulation of cell proliferation IDA
Inferred from Direct Assay
more info
PubMed 
negative regulation of neuron projection development ISS
Inferred from Sequence or Structural Similarity
more info
 
negative regulation of protein ubiquitination IMP
Inferred from Mutant Phenotype
more info
PubMed 
Component Evidence Code Pubs
integral component of membrane IEA
Inferred from Electronic Annotation
more info
 
plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
plasma membrane IDA
Inferred from Direct Assay
more info
PubMed 

General protein information

Preferred Names
major intrinsically disordered Notch2-binding receptor 1
Names
major intrinsically disordered Notch2-associated receptor 1
ubiquitination and mTOR signaling protein

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_015206.3NP_056021.1  major intrinsically disordered Notch2-binding receptor 1

    See identical proteins and their annotated locations for NP_056021.1

    Status: VALIDATED

    Source sequence(s)
    AC105231
    Consensus CDS
    CCDS32306.1
    UniProtKB/Swiss-Prot
    Q9UPX6
    Related
    ENSP00000307461.3, ENST00000305428.8
    Conserved Domains (1) summary
    pfam06789
    Location:759914
    UPF0258; uncharacterized protein family (UPF0258)

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000015.10 Reference GRCh38.p13 Primary Assembly

    Range
    79411557..79472304
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_017022027.1XP_016877516.1  major intrinsically disordered Notch2-binding receptor 1 isoform X1

    UniProtKB/Swiss-Prot
    Q9UPX6
    Conserved Domains (1) summary
    pfam06789
    Location:759914
    UPF0258; uncharacterized protein family (UPF0258)
  2. XM_011521392.1XP_011519694.1  major intrinsically disordered Notch2-binding receptor 1 isoform X1

    See identical proteins and their annotated locations for XP_011519694.1

    UniProtKB/Swiss-Prot
    Q9UPX6
    Conserved Domains (1) summary
    pfam06789
    Location:759914
    UPF0258; uncharacterized protein family (UPF0258)
  3. XM_011521395.2XP_011519697.1  major intrinsically disordered Notch2-binding receptor 1 isoform X1

    See identical proteins and their annotated locations for XP_011519697.1

    UniProtKB/Swiss-Prot
    Q9UPX6
    Conserved Domains (1) summary
    pfam06789
    Location:759914
    UPF0258; uncharacterized protein family (UPF0258)
  4. XM_011521396.2XP_011519698.1  major intrinsically disordered Notch2-binding receptor 1 isoform X1

    See identical proteins and their annotated locations for XP_011519698.1

    UniProtKB/Swiss-Prot
    Q9UPX6
    Conserved Domains (1) summary
    pfam06789
    Location:759914
    UPF0258; uncharacterized protein family (UPF0258)
  5. XM_011521393.3XP_011519695.1  major intrinsically disordered Notch2-binding receptor 1 isoform X1

    See identical proteins and their annotated locations for XP_011519695.1

    UniProtKB/Swiss-Prot
    Q9UPX6
    Conserved Domains (1) summary
    pfam06789
    Location:759914
    UPF0258; uncharacterized protein family (UPF0258)

RNA

  1. XR_931777.1 RNA Sequence

    Related
    ENST00000559272.1
  2. XR_931778.2 RNA Sequence

  3. XR_001751167.1 RNA Sequence

  4. XR_001751168.1 RNA Sequence

  5. XR_002957628.1 RNA Sequence

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