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These reference sequences exist independently of genome builds. Explain
These reference sequences are curated independently of the genome
annotation cycle, so their versions may not match the RefSeq versions in the current
genome build. Identify version mismatches by comparing the version of the RefSeq in
this section to the one reported in Genomic regions,
transcripts, and products above.
mRNA and Protein(s)
-
NM_001185020.1 → NP_001171949.1 serine/threonine-protein kinase WNK1 isoform 2
See identical proteins and their annotated locations for NP_001171949.1
Status: VALIDATED
- Description
- Transcript Variant: This variant (2) has multiple differences in the coding region but maintains the reading frame compared to variant 5. The resulting protein (isoform 2) is shorter but has the same N- and C-termini compared to isoform 5.
- Source sequence(s)
-
AK133738, BC056761, BC138445
- Consensus CDS
-
CCDS85147.1
- UniProtKB/Swiss-Prot
-
P83741
- Related
- ENSMUSP00000145304.2, ENSMUST00000203030.3
- Conserved Domains (3) summary
-
- cd14030
Location:195 → 483
- STKc_WNK1; Catalytic domain of the Serine/Threonine protein kinase, With No Lysine (WNK) 1
- pfam09770
Location:677 → 812
- PAT1; Topoisomerase II-associated protein PAT1
- pfam12202
Location:500 → 563
- OSR1_C; Oxidative-stress-responsive kinase 1 C-terminal domain
-
NM_001185021.1 → NP_001171950.1 serine/threonine-protein kinase WNK1 isoform 3
See identical proteins and their annotated locations for NP_001171950.1
Status: VALIDATED
- Description
- Transcript Variant: This variant (3) has multiple differences in the coding region but maintains the reading frame compared to variant 5. The resulting protein (isoform 3) is shorter but has the same N- and C-termini compared to isoform 5.
- Source sequence(s)
-
AK133738, BC056761, BC145282
- Consensus CDS
-
CCDS51888.1
- UniProtKB/Swiss-Prot
-
P83741
- Related
- ENSMUSP00000086019.6, ENSMUST00000088646.12
- Conserved Domains (2) summary
-
- cd14030
Location:195 → 483
- STKc_WNK1; Catalytic domain of the Serine/Threonine protein kinase, With No Lysine (WNK) 1
- pfam12202
Location:500 → 563
- OSR1_C; Oxidative-stress-responsive kinase 1 C-terminal domain
-
NM_001199083.1 → NP_001186012.1 serine/threonine-protein kinase WNK1 isoform 4
Status: VALIDATED
- Description
- Transcript Variant: This variant (4) has multiple differences in the coding region but maintains the reading frame compared to variant 5. This variant represents the exon combination of the brain and spinal cord variant described in Figure 2F of PubMed ID 18521183. This variant encodes isoform 4, which is shorter than isoform 5 but has the same N- and C-termini.
- Source sequence(s)
-
AC113092, AK133738, BC054836, BC171955, CN693598
- Consensus CDS
-
CCDS57445.1
- UniProtKB/Swiss-Prot
-
P83741
- UniProtKB/TrEMBL
-
Q7TPR2
- Related
- ENSMUSP00000136777.2, ENSMUST00000177761.8
- Conserved Domains (2) summary
-
- cd14030
Location:195 → 483
- STKc_WNK1; Catalytic domain of the Serine/Threonine protein kinase, With No Lysine (WNK) 1
- pfam12202
Location:500 → 563
- OSR1_C; Oxidative-stress-responsive kinase 1 C-terminal domain
-
NM_001199084.1 → NP_001186013.1 serine/threonine-protein kinase WNK1 isoform 5
Status: VALIDATED
- Description
- Transcript Variant: This variant (5) represents the longest transcript and encodes the longest isoform (5). This variant represents the exon combination of the dorsal root ganglia and sciatic nerve variant described in Figure 2F of PubMed ID 18521183.
- Source sequence(s)
-
AC113092, AK133738, BC054836, BC145282, BC171955, CN693598
- Consensus CDS
-
CCDS57444.1
- UniProtKB/Swiss-Prot
-
P83741
- UniProtKB/TrEMBL
-
Q7TPR2
- Related
- ENSMUSP00000086017.7, ENSMUST00000088644.13
- Conserved Domains (2) summary
-
- cd14030
Location:195 → 483
- STKc_WNK1; Catalytic domain of the Serine/Threonine protein kinase, With No Lysine (WNK) 1
- pfam12202
Location:500 → 563
- OSR1_C; Oxidative-stress-responsive kinase 1 C-terminal domain
-
NM_198703.3 → NP_941992.2 serine/threonine-protein kinase WNK1 isoform 1
See identical proteins and their annotated locations for NP_941992.2
Status: VALIDATED
- Description
- Transcript Variant: This variant (1) has multiple differences in the coding region but maintains the reading frame compared to variant 5. The resulting protein (isoform 1) is shorter but has the same N- and C-termini compared to isoform 5.
- Source sequence(s)
-
AK133738, AY309076, BC056761, BC171955
- Consensus CDS
-
CCDS20478.1
- UniProtKB/Swiss-Prot
- P83741, Q6VYA0
- Related
- ENSMUSP00000063001.7, ENSMUST00000060043.13
- Conserved Domains (2) summary
-
- cd14030
Location:195 → 483
- STKc_WNK1; Catalytic domain of the Serine/Threonine protein kinase, With No Lysine (WNK) 1
- pfam12202
Location:500 → 563
- OSR1_C; Oxidative-stress-responsive kinase 1 C-terminal domain
The following sections contain reference sequences that belong to a
specific genome build. Explain
This section includes genomic Reference
Sequences (RefSeqs) from all assemblies on which this gene is annotated, such as
RefSeqs for chromosomes and scaffolds (contigs) from both reference and alternate
assemblies. Model RNAs and proteins are also reported here.
Reference GRCm39 C57BL/6J
Genomic
-
NC_000072.7 Reference GRCm39 C57BL/6J
- Range
-
119900930..120015659 complement
- Download
- GenBank, FASTA, Sequence Viewer (Graphics)
mRNA and Protein(s)
-
XM_036166066.1 → XP_036021959.1 serine/threonine-protein kinase WNK1 isoform X1
- Conserved Domains (3) summary
-
- cd14030
Location:195 → 483
- STKc_WNK1; Catalytic domain of the Serine/Threonine protein kinase, With No Lysine (WNK) 1
- pfam03154
Location:1152 → 1564
- Atrophin-1; Atrophin-1 family
- pfam12202
Location:500 → 563
- OSR1_C; Oxidative-stress-responsive kinase 1 C-terminal domain
-
XM_036166085.1 → XP_036021978.1 serine/threonine-protein kinase WNK1 isoform X30
- Conserved Domains (3) summary
-
- cd14030
Location:195 → 483
- STKc_WNK1; Catalytic domain of the Serine/Threonine protein kinase, With No Lysine (WNK) 1
- pfam03154
Location:1066 → 1478
- Atrophin-1; Atrophin-1 family
- pfam12202
Location:500 → 563
- OSR1_C; Oxidative-stress-responsive kinase 1 C-terminal domain
-
XM_017321556.1 → XP_017177045.1 serine/threonine-protein kinase WNK1 isoform X28
- Conserved Domains (2) summary
-
- cd14030
Location:195 → 483
- STKc_WNK1; Catalytic domain of the Serine/Threonine protein kinase, With No Lysine (WNK) 1
- pfam12202
Location:500 → 563
- OSR1_C; Oxidative-stress-responsive kinase 1 C-terminal domain
-
XM_030255355.1 → XP_030111215.1 serine/threonine-protein kinase WNK1 isoform X25
- Conserved Domains (2) summary
-
- cd14030
Location:195 → 483
- STKc_WNK1; Catalytic domain of the Serine/Threonine protein kinase, With No Lysine (WNK) 1
- pfam12202
Location:500 → 563
- OSR1_C; Oxidative-stress-responsive kinase 1 C-terminal domain
-
XM_036166084.1 → XP_036021977.1 serine/threonine-protein kinase WNK1 isoform X23
- Conserved Domains (3) summary
-
- PRK14949
Location:587 → 957
- PRK14949; DNA polymerase III subunits gamma and tau; Provisional
- cd14030
Location:195 → 483
- STKc_WNK1; Catalytic domain of the Serine/Threonine protein kinase, With No Lysine (WNK) 1
- pfam12202
Location:500 → 563
- OSR1_C; Oxidative-stress-responsive kinase 1 C-terminal domain
-
XM_011241320.2 → XP_011239622.1 serine/threonine-protein kinase WNK1 isoform X20
- Conserved Domains (3) summary
-
- cd14030
Location:195 → 483
- STKc_WNK1; Catalytic domain of the Serine/Threonine protein kinase, With No Lysine (WNK) 1
- pfam03154
Location:646 → 1092
- Atrophin-1; Atrophin-1 family
- pfam12202
Location:500 → 563
- OSR1_C; Oxidative-stress-responsive kinase 1 C-terminal domain
-
XM_017321557.1 → XP_017177046.1 serine/threonine-protein kinase WNK1 isoform X29
- UniProtKB/Swiss-Prot
-
P83741
- Conserved Domains (3) summary
-
- cd14030
Location:195 → 483
- STKc_WNK1; Catalytic domain of the Serine/Threonine protein kinase, With No Lysine (WNK) 1
- pfam09770
Location:677 → 812
- PAT1; Topoisomerase II-associated protein PAT1
- pfam12202
Location:500 → 563
- OSR1_C; Oxidative-stress-responsive kinase 1 C-terminal domain
-
XM_017321555.1 → XP_017177044.1 serine/threonine-protein kinase WNK1 isoform X27
- Conserved Domains (3) summary
-
- cd14030
Location:195 → 483
- STKc_WNK1; Catalytic domain of the Serine/Threonine protein kinase, With No Lysine (WNK) 1
- pfam09770
Location:677 → 812
- PAT1; Topoisomerase II-associated protein PAT1
- pfam12202
Location:500 → 563
- OSR1_C; Oxidative-stress-responsive kinase 1 C-terminal domain
-
XM_017321554.1 → XP_017177043.1 serine/threonine-protein kinase WNK1 isoform X26
- UniProtKB/Swiss-Prot
-
P83741
- Conserved Domains (2) summary
-
- cd14030
Location:195 → 483
- STKc_WNK1; Catalytic domain of the Serine/Threonine protein kinase, With No Lysine (WNK) 1
- pfam12202
Location:500 → 563
- OSR1_C; Oxidative-stress-responsive kinase 1 C-terminal domain
-
XM_017321552.1 → XP_017177041.1 serine/threonine-protein kinase WNK1 isoform X24
- Conserved Domains (2) summary
-
- cd14030
Location:195 → 483
- STKc_WNK1; Catalytic domain of the Serine/Threonine protein kinase, With No Lysine (WNK) 1
- pfam12202
Location:500 → 563
- OSR1_C; Oxidative-stress-responsive kinase 1 C-terminal domain
-
XM_017321550.1 → XP_017177039.1 serine/threonine-protein kinase WNK1 isoform X22
- Conserved Domains (2) summary
-
- cd14030
Location:195 → 483
- STKc_WNK1; Catalytic domain of the Serine/Threonine protein kinase, With No Lysine (WNK) 1
- pfam12202
Location:500 → 563
- OSR1_C; Oxidative-stress-responsive kinase 1 C-terminal domain
-
XM_017321549.1 → XP_017177038.1 serine/threonine-protein kinase WNK1 isoform X21
- UniProtKB/Swiss-Prot
- P83741, Q6VYA0
- Conserved Domains (2) summary
-
- cd14030
Location:195 → 483
- STKc_WNK1; Catalytic domain of the Serine/Threonine protein kinase, With No Lysine (WNK) 1
- pfam12202
Location:500 → 563
- OSR1_C; Oxidative-stress-responsive kinase 1 C-terminal domain
-
XM_017321542.3 → XP_017177031.1 serine/threonine-protein kinase WNK1 isoform X19
- Conserved Domains (2) summary
-
- cd14030
Location:195 → 483
- STKc_WNK1; Catalytic domain of the Serine/Threonine protein kinase, With No Lysine (WNK) 1
- pfam12202
Location:500 → 563
- OSR1_C; Oxidative-stress-responsive kinase 1 C-terminal domain
-
XM_036166082.1 → XP_036021975.1 serine/threonine-protein kinase WNK1 isoform X17
- Conserved Domains (2) summary
-
- cd14030
Location:195 → 483
- STKc_WNK1; Catalytic domain of the Serine/Threonine protein kinase, With No Lysine (WNK) 1
- pfam12202
Location:500 → 563
- OSR1_C; Oxidative-stress-responsive kinase 1 C-terminal domain
-
XM_036166079.1 → XP_036021972.1 serine/threonine-protein kinase WNK1 isoform X14
- Conserved Domains (2) summary
-
- cd14030
Location:195 → 483
- STKc_WNK1; Catalytic domain of the Serine/Threonine protein kinase, With No Lysine (WNK) 1
- pfam12202
Location:500 → 563
- OSR1_C; Oxidative-stress-responsive kinase 1 C-terminal domain
-
XM_036166076.1 → XP_036021969.1 serine/threonine-protein kinase WNK1 isoform X11
- Conserved Domains (3) summary
-
- cd14030
Location:195 → 483
- STKc_WNK1; Catalytic domain of the Serine/Threonine protein kinase, With No Lysine (WNK) 1
- pfam03154
Location:1066 → 1478
- Atrophin-1; Atrophin-1 family
- pfam12202
Location:500 → 563
- OSR1_C; Oxidative-stress-responsive kinase 1 C-terminal domain
-
XM_036166081.1 → XP_036021974.1 serine/threonine-protein kinase WNK1 isoform X16
- Conserved Domains (2) summary
-
- cd14030
Location:195 → 483
- STKc_WNK1; Catalytic domain of the Serine/Threonine protein kinase, With No Lysine (WNK) 1
- pfam12202
Location:500 → 563
- OSR1_C; Oxidative-stress-responsive kinase 1 C-terminal domain
-
XM_036166067.1 → XP_036021960.1 serine/threonine-protein kinase WNK1 isoform X2
- Conserved Domains (3) summary
-
- cd14030
Location:195 → 483
- STKc_WNK1; Catalytic domain of the Serine/Threonine protein kinase, With No Lysine (WNK) 1
- pfam03154
Location:1152 → 1563
- Atrophin-1; Atrophin-1 family
- pfam12202
Location:500 → 563
- OSR1_C; Oxidative-stress-responsive kinase 1 C-terminal domain
-
XM_036166083.1 → XP_036021976.1 serine/threonine-protein kinase WNK1 isoform X18
- Conserved Domains (2) summary
-
- cd14030
Location:195 → 483
- STKc_WNK1; Catalytic domain of the Serine/Threonine protein kinase, With No Lysine (WNK) 1
- pfam12202
Location:500 → 563
- OSR1_C; Oxidative-stress-responsive kinase 1 C-terminal domain
-
XM_036166080.1 → XP_036021973.1 serine/threonine-protein kinase WNK1 isoform X15
- Conserved Domains (2) summary
-
- cd14030
Location:195 → 483
- STKc_WNK1; Catalytic domain of the Serine/Threonine protein kinase, With No Lysine (WNK) 1
- pfam12202
Location:500 → 563
- OSR1_C; Oxidative-stress-responsive kinase 1 C-terminal domain
-
XM_036166078.1 → XP_036021971.1 serine/threonine-protein kinase WNK1 isoform X13
- Conserved Domains (2) summary
-
- cd14030
Location:195 → 483
- STKc_WNK1; Catalytic domain of the Serine/Threonine protein kinase, With No Lysine (WNK) 1
- pfam12202
Location:500 → 563
- OSR1_C; Oxidative-stress-responsive kinase 1 C-terminal domain
-
XM_036166077.1 → XP_036021970.1 serine/threonine-protein kinase WNK1 isoform X12
- Conserved Domains (2) summary
-
- cd14030
Location:195 → 483
- STKc_WNK1; Catalytic domain of the Serine/Threonine protein kinase, With No Lysine (WNK) 1
- pfam12202
Location:500 → 563
- OSR1_C; Oxidative-stress-responsive kinase 1 C-terminal domain
-
XM_036166075.1 → XP_036021968.1 serine/threonine-protein kinase WNK1 isoform X10
- Conserved Domains (2) summary
-
- cd14030
Location:195 → 483
- STKc_WNK1; Catalytic domain of the Serine/Threonine protein kinase, With No Lysine (WNK) 1
- pfam12202
Location:500 → 563
- OSR1_C; Oxidative-stress-responsive kinase 1 C-terminal domain
-
XM_036166071.1 → XP_036021964.1 serine/threonine-protein kinase WNK1 isoform X6
- Conserved Domains (3) summary
-
- cd14030
Location:195 → 483
- STKc_WNK1; Catalytic domain of the Serine/Threonine protein kinase, With No Lysine (WNK) 1
- pfam03154
Location:1152 → 1564
- Atrophin-1; Atrophin-1 family
- pfam12202
Location:500 → 563
- OSR1_C; Oxidative-stress-responsive kinase 1 C-terminal domain
-
XM_036166074.1 → XP_036021967.1 serine/threonine-protein kinase WNK1 isoform X9
- Conserved Domains (2) summary
-
- cd14030
Location:195 → 483
- STKc_WNK1; Catalytic domain of the Serine/Threonine protein kinase, With No Lysine (WNK) 1
- pfam12202
Location:500 → 563
- OSR1_C; Oxidative-stress-responsive kinase 1 C-terminal domain
-
XM_036166073.1 → XP_036021966.1 serine/threonine-protein kinase WNK1 isoform X8
- Conserved Domains (2) summary
-
- cd14030
Location:195 → 483
- STKc_WNK1; Catalytic domain of the Serine/Threonine protein kinase, With No Lysine (WNK) 1
- pfam12202
Location:500 → 563
- OSR1_C; Oxidative-stress-responsive kinase 1 C-terminal domain
-
XM_036166072.1 → XP_036021965.1 serine/threonine-protein kinase WNK1 isoform X7
- Conserved Domains (2) summary
-
- cd14030
Location:195 → 483
- STKc_WNK1; Catalytic domain of the Serine/Threonine protein kinase, With No Lysine (WNK) 1
- pfam12202
Location:500 → 563
- OSR1_C; Oxidative-stress-responsive kinase 1 C-terminal domain
-
XM_036166070.1 → XP_036021963.1 serine/threonine-protein kinase WNK1 isoform X5
- Conserved Domains (3) summary
-
- cd14030
Location:195 → 483
- STKc_WNK1; Catalytic domain of the Serine/Threonine protein kinase, With No Lysine (WNK) 1
- pfam03154
Location:1152 → 1564
- Atrophin-1; Atrophin-1 family
- pfam12202
Location:500 → 563
- OSR1_C; Oxidative-stress-responsive kinase 1 C-terminal domain
-
XM_036166068.1 → XP_036021961.1 serine/threonine-protein kinase WNK1 isoform X3
- Conserved Domains (3) summary
-
- cd14030
Location:195 → 483
- STKc_WNK1; Catalytic domain of the Serine/Threonine protein kinase, With No Lysine (WNK) 1
- pfam03154
Location:1152 → 1564
- Atrophin-1; Atrophin-1 family
- pfam12202
Location:500 → 563
- OSR1_C; Oxidative-stress-responsive kinase 1 C-terminal domain
-
XM_036166069.1 → XP_036021962.1 serine/threonine-protein kinase WNK1 isoform X4
- Conserved Domains (3) summary
-
- cd14030
Location:195 → 483
- STKc_WNK1; Catalytic domain of the Serine/Threonine protein kinase, With No Lysine (WNK) 1
- pfam03154
Location:1152 → 1564
- Atrophin-1; Atrophin-1 family
- pfam12202
Location:500 → 563
- OSR1_C; Oxidative-stress-responsive kinase 1 C-terminal domain
The following Reference Sequences have been suppressed. Explain
These RefSeqs were suppressed for the
cited reason(s). Suppressed RefSeqs do not appear in BLAST databases, related
sequence links, or BLAST links (BLink), but may still be retrieved by clicking on
their accession.version below.
-
NM_001037155.1: Suppressed sequence
- Description
- NM_001037155.1: This RefSeq was permanently suppressed because it represents a nervous system-specific exon of WNK1, GeneID 232341, but there currently is insufficient support for a transcript containing this exon.