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Zfp637 zinc finger protein 637 [ Mus musculus (house mouse) ]

Gene ID: 232337, updated on 30-Apr-2024

Summary

Official Symbol
Zfp637provided by MGI
Official Full Name
zinc finger protein 637provided by MGI
Primary source
MGI:MGI:2448537
See related
Ensembl:ENSMUSG00000059689 AllianceGenome:MGI:2448537
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Znf32
Summary
Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be located in nucleus. Is expressed in diencephalon lateral wall ventricular layer; medulla oblongata basal plate ventricular layer; midbrain ventricular layer; pons ventricular layer; and telencephalon ventricular layer. Orthologous to human ZNF32 (zinc finger protein 32). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Ubiquitous expression in CNS E18 (RPKM 16.4), CNS E14 (RPKM 16.1) and 28 other tissues See more
Orthologs
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Genomic context

See Zfp637 in Genome Data Viewer
Location:
6 F1; 6 55.59 cM
Exon count:
5
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 6 NC_000072.7 (117818165..117822917)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 6 NC_000072.6 (117840588..117845957)

Chromosome 6 - NC_000072.7Genomic Context describing neighboring genes Neighboring gene RIKEN cDNA 1700030F04 gene Neighboring gene STARR-seq mESC enhancer starr_17118 Neighboring gene STARR-seq mESC enhancer starr_17119 Neighboring gene STARR-seq mESC enhancer starr_17120 Neighboring gene gem nuclear organelle associated protein 6, pseudogene Neighboring gene CapStarr-seq enhancer MGSCv37_chr6:117791080-117791189 Neighboring gene zinc finger protein 239 Neighboring gene STARR-seq mESC enhancer starr_17123 Neighboring gene predicted gene, 38883 Neighboring gene predicted gene, 38882

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Endonuclease-mediated (3) 

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001346647.2NP_001333576.1  zinc finger protein 32 isoform 1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) encodes the longest isoform (1). Variants 1 and 2 encode the same isoform (1).
    Source sequence(s)
    AC153583, AC153918
    Consensus CDS
    CCDS85139.1
    UniProtKB/Swiss-Prot
    Q80V23
    Related
    ENSMUSP00000108481.2, ENSMUST00000112860.2
    Conserved Domains (2) summary
    COG5048
    Location:60251
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:92112
    ZF_C2H2; C2H2 Zn finger [structural motif]
  2. NM_001346648.2NP_001333577.1  zinc finger protein 32 isoform 1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) differs in the 5' UTR, compared to variant 1. Variants 1 and 2 encode the same isoform (1).
    Source sequence(s)
    AC153583, AC153918
    Consensus CDS
    CCDS85139.1
    UniProtKB/Swiss-Prot
    Q80V23
    Related
    ENSMUSP00000152569.2, ENSMUST00000223041.2
    Conserved Domains (2) summary
    COG5048
    Location:60251
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:92112
    ZF_C2H2; C2H2 Zn finger [structural motif]
  3. NM_001346649.2NP_001333578.1  zinc finger protein 32 isoform 2

    Status: VALIDATED

    Description
    Transcript Variant: This variant (3) differs in the 5' UTR and uses an alternate splice site in the 3' coding region, compared to variant 1. It encodes isoform 2, which is shorter than isoform 1. Variants 3, 4 and 5 encode the same isoform (2).
    Source sequence(s)
    AC153583, AC153918
    Consensus CDS
    CCDS39607.1
    UniProtKB/Swiss-Prot
    Q3UIS3, Q80V23
    Related
    ENSMUSP00000108482.2, ENSMUST00000112861.8
    Conserved Domains (2) summary
    COG5048
    Location:46237
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:7898
    ZF_C2H2; C2H2 Zn finger [structural motif]
  4. NM_001346650.2NP_001333579.1  zinc finger protein 32 isoform 2

    Status: VALIDATED

    Description
    Transcript Variant: This variant (4) uses an alternate splice site in the 3' coding region, compared to variant 1. It encodes isoform 2, which is shorter than isoform 1. Variants 3, 4 and 5 encode the same isoform (2).
    Source sequence(s)
    AC153583, AC153918
    Consensus CDS
    CCDS39607.1
    UniProtKB/Swiss-Prot
    Q3UIS3, Q80V23
    Conserved Domains (2) summary
    COG5048
    Location:46237
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:7898
    ZF_C2H2; C2H2 Zn finger [structural motif]
  5. NM_001346651.2NP_001333580.1  zinc finger protein 32 isoform 3

    Status: VALIDATED

    Description
    Transcript Variant: This variant (6) differs in the 5' UTR, lacks a portion of the 5' coding region and initiates translation at a downstream start codon, compared to variant 1. It encodes isoform 3, which has a shorter N-terminus, compared to isoform 1. Variants 6, 7 and 8 encode the same isoform (3).
    Source sequence(s)
    AC153583, AC153918
    UniProtKB/TrEMBL
    Q05CR8
    Conserved Domains (2) summary
    COG5048
    Location:21212
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:5373
    ZF_C2H2; C2H2 Zn finger [structural motif]
  6. NM_001346652.2NP_001333581.1  zinc finger protein 32 isoform 3

    Status: VALIDATED

    Description
    Transcript Variant: This variant (7) differs in the 5' UTR, lacks a portion of the 5' coding region and initiates translation at a downstream start codon, compared to variant 1. It encodes isoform 3, which has a shorter N-terminus, compared to isoform 1. Variants 6, 7 and 8 encode the same isoform (3).
    Source sequence(s)
    AC153583, AC153918
    UniProtKB/TrEMBL
    Q05CR8
    Conserved Domains (2) summary
    COG5048
    Location:21212
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:5373
    ZF_C2H2; C2H2 Zn finger [structural motif]
  7. NM_001346653.2NP_001333582.1  zinc finger protein 32 isoform 3

    Status: VALIDATED

    Description
    Transcript Variant: This variant (8) differs in the 5' UTR, lacks a portion of the 5' coding region and initiates translation at a downstream start codon, compared to variant 1. It encodes isoform 3, which has a shorter N-terminus, compared to isoform 1. Variants 6, 7 and 8 encode the same isoform (3).
    Source sequence(s)
    AC153583, AC153918
    UniProtKB/TrEMBL
    Q05CR8
    Conserved Domains (2) summary
    COG5048
    Location:21212
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:5373
    ZF_C2H2; C2H2 Zn finger [structural motif]
  8. NM_001411605.1NP_001398534.1  zinc finger protein 32 isoform 1

    Status: VALIDATED

    Source sequence(s)
    AC153583, AC153918
  9. NM_001411609.1NP_001398538.1  zinc finger protein 32 isoform 2

    Status: VALIDATED

    Source sequence(s)
    AC153583, AC153918
    UniProtKB/Swiss-Prot
    Q3UIS3, Q80V23
  10. NM_001411610.1NP_001398539.1  zinc finger protein 32 isoform 2

    Status: VALIDATED

    Source sequence(s)
    AC153583, AC153918
    UniProtKB/Swiss-Prot
    Q3UIS3, Q80V23
  11. NM_001411611.1NP_001398540.1  zinc finger protein 32 isoform 2

    Status: VALIDATED

    Source sequence(s)
    AC153583, AC153918
    UniProtKB/Swiss-Prot
    Q3UIS3, Q80V23
  12. NM_001411613.1NP_001398542.1  zinc finger protein 32 isoform 3

    Status: VALIDATED

    Source sequence(s)
    AC153583, AC153918
    UniProtKB/TrEMBL
    Q05CR8
  13. NM_001411614.1NP_001398543.1  zinc finger protein 32 isoform 3

    Status: VALIDATED

    Source sequence(s)
    AC153583, AC153918
    UniProtKB/TrEMBL
    Q05CR8
  14. NM_001411615.1NP_001398544.1  zinc finger protein 32 isoform 3

    Status: VALIDATED

    Source sequence(s)
    AC153583, AC153918
    UniProtKB/TrEMBL
    Q05CR8
  15. NM_001411616.1NP_001398545.1  zinc finger protein 32 isoform 3

    Status: VALIDATED

    Source sequence(s)
    AC153583, AC153918
    UniProtKB/TrEMBL
    Q05CR8
  16. NM_001411617.1NP_001398546.1  zinc finger protein 32 isoform 3

    Status: VALIDATED

    Source sequence(s)
    AC153583, AC153918
    UniProtKB/TrEMBL
    Q05CR8
  17. NM_001411618.1NP_001398547.1  zinc finger protein 32 isoform 3

    Status: VALIDATED

    Source sequence(s)
    AC153583, AC153918
    UniProtKB/TrEMBL
    Q05CR8
  18. NM_177684.4NP_808352.1  zinc finger protein 32 isoform 2

    See identical proteins and their annotated locations for NP_808352.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (5) differs in the 5' UTR and uses an alternate splice site in the 3' coding region, compared to variant 1. It encodes isoform 2, which is shorter than isoform 1. Variants 3, 4 and 5 encode the same isoform (2).
    Source sequence(s)
    AC153583, AC153918
    Consensus CDS
    CCDS39607.1
    UniProtKB/Swiss-Prot
    Q3UIS3, Q80V23
    Related
    ENSMUSP00000130144.2, ENSMUST00000164472.8
    Conserved Domains (2) summary
    COG5048
    Location:46237
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:7898
    ZF_C2H2; C2H2 Zn finger [structural motif]

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000072.7 Reference GRCm39 C57BL/6J

    Range
    117818165..117822917
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006506017.4XP_006506080.1  zinc finger protein 32 isoform X1

    See identical proteins and their annotated locations for XP_006506080.1

    UniProtKB/Swiss-Prot
    Q80V23
    Conserved Domains (2) summary
    COG5048
    Location:60251
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:92112
    ZF_C2H2; C2H2 Zn finger [structural motif]
  2. XM_036166061.1XP_036021954.1  zinc finger protein 32 isoform X3

    UniProtKB/TrEMBL
    Q05CR8
    Conserved Domains (2) summary
    COG5048
    Location:21212
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:5373
    ZF_C2H2; C2H2 Zn finger [structural motif]
  3. XM_030255351.2XP_030111211.1  zinc finger protein 32 isoform X2

    UniProtKB/Swiss-Prot
    Q3UIS3, Q80V23
    Conserved Domains (2) summary
    COG5048
    Location:46237
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:7898
    ZF_C2H2; C2H2 Zn finger [structural motif]