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Fgd5 FYVE, RhoGEF and PH domain containing 5 [ Mus musculus (house mouse) ]

Gene ID: 232237, updated on 31-Jan-2019

Summary

Official Symbol
Fgd5provided by MGI
Official Full Name
FYVE, RhoGEF and PH domain containing 5provided by MGI
Primary source
MGI:MGI:2443369
See related
Ensembl:ENSMUSG00000034037
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
ZFYVE23; mFLJ00274; C330025N11Rik
Expression
Ubiquitous expression in lung adult (RPKM 11.1), subcutaneous fat pad adult (RPKM 5.0) and 27 other tissues See more
Orthologs

Genomic context

See Fgd5 in Genome Data Viewer
Location:
6; 6 D1
Exon count:
21
Annotation release Status Assembly Chr Location
106 current GRCm38.p4 (GCF_000001635.24) 6 NC_000072.6 (91978824..92076005)
Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 6 NC_000072.5 (91937104..92025999)

Chromosome 6 - NC_000072.6Genomic Context describing neighboring genes Neighboring gene RIKEN cDNA 4930590J08 gene Neighboring gene coiled-coil domain containing 174 Neighboring gene nuclear receptor subfamily 2, group C, member 2 Neighboring gene predicted gene, 46967 Neighboring gene mitochondrial ribosomal protein S25

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)

General gene information

Markers

Homology

Clone Names

  • FLJ00274

Gene Ontology Provided by MGI

Function Evidence Code Pubs
Rho guanyl-nucleotide exchange factor activity IEA
Inferred from Electronic Annotation
more info
 
guanyl-nucleotide exchange factor activity IEA
Inferred from Electronic Annotation
more info
 
metal ion binding IEA
Inferred from Electronic Annotation
more info
 
molecular_function ND
No biological Data available
more info
 
Process Evidence Code Pubs
biological_process ND
No biological Data available
more info
 
regulation of Rho protein signal transduction IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
Golgi apparatus IEA
Inferred from Electronic Annotation
more info
 
cell projection IEA
Inferred from Electronic Annotation
more info
 
cellular_component ND
No biological Data available
more info
 
cytoplasm IEA
Inferred from Electronic Annotation
more info
 
cytoskeleton IEA
Inferred from Electronic Annotation
more info
 
endoplasmic reticulum IEA
Inferred from Electronic Annotation
more info
 
endosome IEA
Inferred from Electronic Annotation
more info
 
membrane IEA
Inferred from Electronic Annotation
more info
 
plasma membrane IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
FYVE, RhoGEF and PH domain-containing protein 5

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_172731.3NP_766319.3  FYVE, RhoGEF and PH domain-containing protein 5

    Status: VALIDATED

    Source sequence(s)
    AK086031, AW046885, BB612302, BC060664, CB246280, CN446877, CX568970
    Consensus CDS
    CCDS20371.2
    UniProtKB/Swiss-Prot
    Q80UZ0
    UniProtKB/TrEMBL
    E9QKY4
    Related
    ENSMUSP00000086748.2, ENSMUST00000089334.8
    Conserved Domains (5) summary
    cd13237
    Location:14181508
    PH2_FGD5_FGD6; FYVE, RhoGEF and PH domain containing/faciogenital dysplasia proteins 5 and 6 pleckstrin homology (PH) domain, C-terminus
    pfam00169
    Location:11671258
    PH; PH domain
    pfam00621
    Location:9461134
    RhoGEF; RhoGEF domain
    cl17171
    Location:11521274
    PH-like; Pleckstrin homology-like domain
    cl22851
    Location:12881354
    PHD_SF; PHD finger superfamily

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 106

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm38.p4 C57BL/6J

Genomic

  1. NC_000072.6 Reference GRCm38.p4 C57BL/6J

    Range
    91978824..92076005
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006506000.3XP_006506063.1  FYVE, RhoGEF and PH domain-containing protein 5 isoform X1

    Conserved Domains (5) summary
    cd13237
    Location:14191509
    PH2_FGD5_FGD6; FYVE, RhoGEF and PH domain containing/faciogenital dysplasia proteins 5 and 6 pleckstrin homology (PH) domain, C-terminus
    pfam00169
    Location:11681259
    PH; PH domain
    pfam00621
    Location:9461135
    RhoGEF; RhoGEF domain
    cl17171
    Location:11531275
    PH-like; Pleckstrin homology-like domain
    cl22851
    Location:12891355
    PHD_SF; PHD finger superfamily
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