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Hdac11 histone deacetylase 11 [ Mus musculus (house mouse) ]

Gene ID: 232232, updated on 8-Dec-2018

Summary

Official Symbol
Hdac11provided by MGI
Official Full Name
histone deacetylase 11provided by MGI
Primary source
MGI:MGI:2385252
See related
Ensembl:ENSMUSG00000034245
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Expression
Ubiquitous expression in testis adult (RPKM 59.4), cerebellum adult (RPKM 42.4) and 27 other tissues See more
Orthologs

Genomic context

See Hdac11 in Genome Data Viewer
Location:
6; 6 D1
Exon count:
11
Annotation release Status Assembly Chr Location
106 current GRCm38.p4 (GCF_000001635.24) 6 NC_000072.6 (91156670..91174692)
Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 6 NC_000072.5 (91106809..91124677)

Chromosome 6 - NC_000072.6Genomic Context describing neighboring genes Neighboring gene nucleoporin 210 Neighboring gene predicted gene, 30364 Neighboring gene fibulin 2 Neighboring gene 60S ribosomal protein L23a pseudogene

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Targeted (2)  1 citation
  • Endonuclease-mediated (2) 

Pathways from BioSystems

  • Alcoholism, organism-specific biosystem (from KEGG)
    Alcoholism, organism-specific biosystemAlcoholism, also called dependence on alcohol (ethanol), is a chronic relapsing disorder that is progressive and has serious detrimental health outcomes. As one of the primary mediators of the reward...
  • Alcoholism, conserved biosystem (from KEGG)
    Alcoholism, conserved biosystemAlcoholism, also called dependence on alcohol (ethanol), is a chronic relapsing disorder that is progressive and has serious detrimental health outcomes. As one of the primary mediators of the reward...
  • Viral carcinogenesis, organism-specific biosystem (from KEGG)
    Viral carcinogenesis, organism-specific biosystemThere is a strong association between viruses and the development of human malignancies. We now know that at least six human viruses, Epstein-Barr virus (EBV), hepatitis B virus (HBV), hepatitis C vi...
  • Viral carcinogenesis, conserved biosystem (from KEGG)
    Viral carcinogenesis, conserved biosystemThere is a strong association between viruses and the development of human malignancies. We now know that at least six human viruses, Epstein-Barr virus (EBV), hepatitis B virus (HBV), hepatitis C vi...

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Homology

Clone Names

  • MGC27683

Gene Ontology Provided by MGI

Function Evidence Code Pubs
NAD-dependent histone deacetylase activity (H3-K14 specific) IEA
Inferred from Electronic Annotation
more info
 
histone deacetylase activity ISO
Inferred from Sequence Orthology
more info
 
histone deacetylase activity TAS
Traceable Author Statement
more info
PubMed 
hydrolase activity IEA
Inferred from Electronic Annotation
more info
 
protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
transcription factor binding TAS
Traceable Author Statement
more info
PubMed 
Process Evidence Code Pubs
chromatin organization TAS
Traceable Author Statement
more info
PubMed 
histone deacetylation ISO
Inferred from Sequence Orthology
more info
 
oligodendrocyte development ISO
Inferred from Sequence Orthology
more info
 
Component Evidence Code Pubs
cytoplasm TAS
Traceable Author Statement
more info
PubMed 
histone deacetylase complex ISO
Inferred from Sequence Orthology
more info
 
histone deacetylase complex TAS
Traceable Author Statement
more info
PubMed 
nucleus ISO
Inferred from Sequence Orthology
more info
 
nucleus TAS
Traceable Author Statement
more info
PubMed 
plasma membrane ISO
Inferred from Sequence Orthology
more info
 

General protein information

Preferred Names
histone deacetylase 11
Names
HD11
NP_659168.1
XP_006506058.1
XP_017177024.1
XP_017177025.1

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_144919.2NP_659168.1  histone deacetylase 11

    See identical proteins and their annotated locations for NP_659168.1

    Status: PROVISIONAL

    Source sequence(s)
    AC110256, AC131764
    Consensus CDS
    CCDS20366.1
    UniProtKB/Swiss-Prot
    Q91WA3
    UniProtKB/TrEMBL
    Q543U1
    Related
    ENSMUSP00000043828.4, ENSMUST00000041736.10
    Conserved Domains (1) summary
    cd09993
    Location:35319
    HDAC_classIV; Histone deacetylase class IV also known as histone deacetylase 11

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 106

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm38.p4 C57BL/6J

Genomic

  1. NC_000072.6 Reference GRCm38.p4 C57BL/6J

    Range
    91156670..91174692
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_017321535.1XP_017177024.1  histone deacetylase 11 isoform X2

  2. XM_017321536.1XP_017177025.1  histone deacetylase 11 isoform X3

  3. XM_006505995.1XP_006506058.1  histone deacetylase 11 isoform X1

    Conserved Domains (1) summary
    cd09993
    Location:16197
    HDAC_classIV; Histone deacetylase class IV also known as histone deacetylase 11
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