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Hdac11 histone deacetylase 11 [ Mus musculus (house mouse) ]

Gene ID: 232232, updated on 8-Feb-2024

Summary

Official Symbol
Hdac11provided by MGI
Official Full Name
histone deacetylase 11provided by MGI
Primary source
MGI:MGI:2385252
See related
Ensembl:ENSMUSG00000034245 AllianceGenome:MGI:2385252
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Summary
Predicted to enable histone deacetylase activity. Predicted to be involved in histone deacetylation and oligodendrocyte development. Predicted to be located in nucleus and plasma membrane. Predicted to be part of histone deacetylase complex. Orthologous to human HDAC11 (histone deacetylase 11). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Ubiquitous expression in testis adult (RPKM 59.4), cerebellum adult (RPKM 42.4) and 27 other tissues See more
Orthologs
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Genomic context

See Hdac11 in Genome Data Viewer
Location:
6 D1; 6 40.38 cM
Exon count:
11
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 6 NC_000072.7 (91133652..91151674)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 6 NC_000072.6 (91156670..91174692)

Chromosome 6 - NC_000072.7Genomic Context describing neighboring genes Neighboring gene nucleoporin 210 Neighboring gene STARR-positive B cell enhancer ABC_E6455 Neighboring gene CapStarr-seq enhancer MGSCv37_chr6:91064892-91065075 Neighboring gene predicted gene, 53297 Neighboring gene predicted gene, 30364 Neighboring gene VISTA enhancer mm1314 Neighboring gene predicted gene, 53298 Neighboring gene fibulin 2

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)

Pathways from PubChem

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Clone Names

  • MGC27683

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables DNA-binding transcription factor binding TAS
Traceable Author Statement
more info
PubMed 
enables histone deacetylase activity IBA
Inferred from Biological aspect of Ancestor
more info
 
enables histone deacetylase activity ISO
Inferred from Sequence Orthology
more info
 
enables histone deacetylase activity TAS
Traceable Author Statement
more info
PubMed 
enables hydrolase activity IEA
Inferred from Electronic Annotation
more info
 
enables protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
Process Evidence Code Pubs
involved_in chromatin organization TAS
Traceable Author Statement
more info
PubMed 
involved_in oligodendrocyte development ISO
Inferred from Sequence Orthology
more info
 
Component Evidence Code Pubs
located_in cytoplasm TAS
Traceable Author Statement
more info
PubMed 
part_of histone deacetylase complex IBA
Inferred from Biological aspect of Ancestor
more info
 
part_of histone deacetylase complex ISO
Inferred from Sequence Orthology
more info
 
part_of histone deacetylase complex TAS
Traceable Author Statement
more info
PubMed 
located_in nucleus ISO
Inferred from Sequence Orthology
more info
 
located_in nucleus TAS
Traceable Author Statement
more info
PubMed 
located_in plasma membrane ISO
Inferred from Sequence Orthology
more info
 

General protein information

Preferred Names
histone deacetylase 11
Names
HD11
NP_659168.1
XP_036021947.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_144919.2NP_659168.1  histone deacetylase 11

    See identical proteins and their annotated locations for NP_659168.1

    Status: PROVISIONAL

    Source sequence(s)
    AC110256, AC131764
    Consensus CDS
    CCDS20366.1
    UniProtKB/Swiss-Prot
    Q91WA3
    UniProtKB/TrEMBL
    Q543U1
    Related
    ENSMUSP00000043828.5, ENSMUST00000041736.11
    Conserved Domains (1) summary
    cd09993
    Location:35319
    HDAC_classIV; Histone deacetylase class IV also known as histone deacetylase 11

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000072.7 Reference GRCm39 C57BL/6J

    Range
    91133652..91151674
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_036166054.1XP_036021947.1  histone deacetylase 11 isoform X1

    Conserved Domains (1) summary
    cd09993
    Location:16197
    HDAC_classIV; Histone deacetylase class IV also known as histone deacetylase 11

RNA

  1. XR_003956189.1 RNA Sequence

  2. XR_003956190.1 RNA Sequence