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RRP12 ribosomal RNA processing 12 homolog [ Homo sapiens (human) ]

Gene ID: 23223, updated on 21-Dec-2019

Summary

Official Symbol
RRP12provided by HGNC
Official Full Name
ribosomal RNA processing 12 homologprovided by HGNC
Primary source
HGNC:HGNC:29100
See related
Ensembl:ENSG00000052749 MIM:617723
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
KIAA0690
Expression
Broad expression in bone marrow (RPKM 30.6), testis (RPKM 10.2) and 25 other tissues See more
Orthologs

Genomic context

See RRP12 in Genome Data Viewer
Location:
10q24.1
Exon count:
34
Annotation release Status Assembly Chr Location
109.20191205 current GRCh38.p13 (GCF_000001405.39) 10 NC_000010.11 (97356357..97401370, complement)
105 previous assembly GRCh37.p13 (GCF_000001405.25) 10 NC_000010.10 (99116458..99161127, complement)

Chromosome 10 - NC_000010.11Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC105378448 Neighboring gene FRAT regulator of WNT signaling pathway 2 Neighboring gene ribosomal protein L34 pseudogene 20 Neighboring gene uncharacterized LOC644215 Neighboring gene phosphoglycerate mutase 1

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Clone Names

  • FLJ20231, DKFZp762P1116

Gene Ontology Provided by GOA

Function Evidence Code Pubs
RNA binding HDA PubMed 
Component Evidence Code Pubs
cytosol IDA
Inferred from Direct Assay
more info
 
integral component of membrane IEA
Inferred from Electronic Annotation
more info
 
intracellular membrane-bounded organelle IDA
Inferred from Direct Assay
more info
 
nuclear membrane IEA
Inferred from Electronic Annotation
more info
 
nucleolus IDA
Inferred from Direct Assay
more info
 
plasma membrane IDA
Inferred from Direct Assay
more info
 

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001145114.1NP_001138586.1  RRP12-like protein isoform 2

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) lacks two alternate in-frame exons in the 5' coding region, compared to variant 1. This results in a shorter protein (isoform 2), compared to isoform 1.
    Source sequence(s)
    AK022496, AK296315, AL355490, BC012745
    Consensus CDS
    CCDS44467.1
    UniProtKB/Swiss-Prot
    Q5JTH9
    UniProtKB/TrEMBL
    B3KMR5
    Related
    ENSP00000414863.1, ENST00000414986.5
    Conserved Domains (1) summary
    pfam08161
    Location:411608
    NUC173; NUC173 domain
  2. NM_001284337.2NP_001271266.1  RRP12-like protein isoform 3

    Status: VALIDATED

    Description
    Transcript Variant: This variant (3) lacks three alternate in-frame exons in the 5' coding region, compared to variant 1. This results in a shorter protein (isoform 3), compared to isoform 1.
    Source sequence(s)
    AB014590, AK022496, AL355490, BC012745, DA227012
    Consensus CDS
    CCDS60605.1
    UniProtKB/Swiss-Prot
    Q5JTH9
    UniProtKB/TrEMBL
    B3KMR5
    Related
    ENSP00000324315.6, ENST00000315563.10
    Conserved Domains (1) summary
    pfam08161
    Location:372569
    NUC173; NUC173 domain
  3. NM_015179.4NP_055994.2  RRP12-like protein isoform 1

    See identical proteins and their annotated locations for NP_055994.2

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) represents the longest transcript and encodes the longest isoform (1).
    Source sequence(s)
    AK022496, AK056614, BC012745, DA231457
    Consensus CDS
    CCDS7457.1
    UniProtKB/Swiss-Prot
    Q5JTH9
    UniProtKB/TrEMBL
    B3KMR5
    Related
    ENSP00000360031.4, ENST00000370992.8
    Conserved Domains (1) summary
    pfam08161
    Location:472669
    NUC173; NUC173 domain

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.20191205

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000010.11 Reference GRCh38.p13 Primary Assembly

    Range
    97356357..97401370 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_024447920.1XP_024303688.1  RRP12-like protein isoform X2

    Conserved Domains (1) summary
    pfam08161
    Location:443643
    NUC173; NUC173 domain
  2. XM_024447919.1XP_024303687.1  RRP12-like protein isoform X1

    Conserved Domains (1) summary
    pfam08161
    Location:471671
    NUC173; NUC173 domain
  3. XM_011539556.2XP_011537858.1  RRP12-like protein isoform X3

    Conserved Domains (1) summary
    pfam08161
    Location:472669
    NUC173; NUC173 domain

RNA

  1. XR_001747071.1 RNA Sequence

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