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PRRC2C proline rich coiled-coil 2C [ Homo sapiens (human) ]

Gene ID: 23215, updated on 4-Nov-2018

Summary

Official Symbol
PRRC2Cprovided by HGNC
Official Full Name
proline rich coiled-coil 2Cprovided by HGNC
Primary source
HGNC:HGNC:24903
See related
Ensembl:ENSG00000117523 MIM:617373; Vega:OTTHUMG00000034665
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
XTP2; BAT2D1; BAT2L2; BAT2-iso
Expression
Ubiquitous expression in bone marrow (RPKM 24.0), lymph node (RPKM 17.9) and 25 other tissues See more
Orthologs

Genomic context

See PRRC2C in Genome Data Viewer
Location:
1q24.3
Exon count:
36
Annotation release Status Assembly Chr Location
109 current GRCh38.p12 (GCF_000001405.38) 1 NC_000001.11 (171485496..171593511)
105 previous assembly GRCh37.p13 (GCF_000001405.25) 1 NC_000001.10 (171454652..171562650)

Chromosome 1 - NC_000001.11Genomic Context describing neighboring genes Neighboring gene RNA, U6 small nuclear 290, pseudogene Neighboring gene cytochrome c, somatic pseudogene 53 Neighboring gene RNA, 7SL, cytoplasmic 425, pseudogene Neighboring gene myocilin opposite strand Neighboring gene myocilin

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Jun 15 11:32:44 2016

Bibliography

GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

HIV-1 interactions

Protein interactions

Protein Gene Interaction Pubs
Pr55(Gag) gag Cellular biotinylated proline-rich coiled-coil 2C (PRRC2C) protein is incorporated into HIV-1 Gag virus-like particles PubMed
gag Interaction of HIV-1 Gag with proline-rich coiled-coil 2C (PRRC2C, BAT2L2) is identified in a series of six affinity purification/mass spectrometry screens PubMed

Go to the HIV-1, Human Interaction Database

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Gene Ontology Provided by GOA

Function Evidence Code Pubs
RNA binding HDA PubMed 
protein C-terminus binding IPI
Inferred from Physical Interaction
more info
PubMed 
Process Evidence Code Pubs
hematopoietic progenitor cell differentiation IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Component Evidence Code Pubs
cytosol IDA
Inferred from Direct Assay
more info
 
membrane HDA PubMed 

General protein information

Preferred Names
protein PRRC2C
Names
BAT2 domain containing 1
BAT2 domain-containing protein 1
HBV X-transactivated gene 2 protein
HBV XAg-transactivated protein 2
HBxAg transactivated protein 2
HLA-B-associated transcript 2-like 2
proline-rich and coiled-coil-containing protein 2C
protein BAT2-like 2

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_015172.3NP_055987.2  protein PRRC2C

    See identical proteins and their annotated locations for NP_055987.2

    Status: VALIDATED

    Source sequence(s)
    AF488829, AL133635, AL162004, BC001260, CB158511
    Consensus CDS
    CCDS1296.2
    UniProtKB/Swiss-Prot
    Q9Y520
    Related
    ENSP00000343629.4, OTTHUMP00000213044, ENST00000338920.8, OTTHUMT00000314826
    Conserved Domains (1) summary
    pfam07001
    Location:1160
    BAT2_N; BAT2 N-terminus

RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 109 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p12 Primary Assembly

Genomic

  1. NC_000001.11 Reference GRCh38.p12 Primary Assembly

    Range
    171485496..171593511
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_005245020.2XP_005245077.1  protein PRRC2C isoform X8

    Conserved Domains (2) summary
    pfam09606
    Location:22582642
    Med15; ARC105 or Med15 subunit of Mediator complex non-fungal
    pfam07001
    Location:1162
    BAT2_N; BAT2 N-terminus
  2. XM_005245015.2XP_005245072.1  protein PRRC2C isoform X1

    Conserved Domains (2) summary
    pfam09606
    Location:22582642
    Med15; ARC105 or Med15 subunit of Mediator complex non-fungal
    pfam07001
    Location:1162
    BAT2_N; BAT2 N-terminus
  3. XM_005245025.2XP_005245082.1  protein PRRC2C isoform X13

    Conserved Domains (2) summary
    pfam09606
    Location:22582642
    Med15; ARC105 or Med15 subunit of Mediator complex non-fungal
    pfam07001
    Location:1162
    BAT2_N; BAT2 N-terminus
  4. XM_005245023.2XP_005245080.1  protein PRRC2C isoform X10

    Conserved Domains (2) summary
    pfam09606
    Location:22582642
    Med15; ARC105 or Med15 subunit of Mediator complex non-fungal
    pfam07001
    Location:1162
    BAT2_N; BAT2 N-terminus
  5. XM_005245028.2XP_005245085.1  protein PRRC2C isoform X16

    Conserved Domains (2) summary
    pfam09606
    Location:22582642
    Med15; ARC105 or Med15 subunit of Mediator complex non-fungal
    pfam07001
    Location:1162
    BAT2_N; BAT2 N-terminus
  6. XM_005245027.2XP_005245084.1  protein PRRC2C isoform X15

    Conserved Domains (2) summary
    pfam09606
    Location:22582642
    Med15; ARC105 or Med15 subunit of Mediator complex non-fungal
    pfam07001
    Location:1162
    BAT2_N; BAT2 N-terminus
  7. XM_017000761.1XP_016856250.1  protein PRRC2C isoform X9

  8. XM_005245017.2XP_005245074.1  protein PRRC2C isoform X3

    UniProtKB/Swiss-Prot
    Q9Y520
    Conserved Domains (1) summary
    pfam07001
    Location:1162
    BAT2_N; BAT2 N-terminus
  9. XM_005245026.2XP_005245083.1  protein PRRC2C isoform X14

    Conserved Domains (1) summary
    pfam07001
    Location:1162
    BAT2_N; BAT2 N-terminus
  10. XM_005245024.2XP_005245081.1  protein PRRC2C isoform X11

    UniProtKB/TrEMBL
    E7EPN9
    Related
    ENSP00000356716.3, OTTHUMP00000213041, ENST00000367742.7, OTTHUMT00000083864
    Conserved Domains (1) summary
    pfam07001
    Location:1162
    BAT2_N; BAT2 N-terminus
  11. XM_005245029.2XP_005245086.1  protein PRRC2C isoform X17

    Conserved Domains (1) summary
    pfam07001
    Location:1162
    BAT2_N; BAT2 N-terminus
  12. XM_005245019.2XP_005245076.1  protein PRRC2C isoform X7

    Conserved Domains (2) summary
    pfam09606
    Location:22242608
    Med15; ARC105 or Med15 subunit of Mediator complex non-fungal
    pfam07001
    Location:1162
    BAT2_N; BAT2 N-terminus
  13. XM_017000762.1XP_016856251.1  protein PRRC2C isoform X12

  14. XM_005245018.3XP_005245075.1  protein PRRC2C isoform X4

    Conserved Domains (2) summary
    pfam09606
    Location:22532637
    Med15; ARC105 or Med15 subunit of Mediator complex non-fungal
    pfam07001
    Location:1157
    BAT2_N; BAT2 N-terminus
  15. XM_005245016.5XP_005245073.1  protein PRRC2C isoform X2

    Conserved Domains (2) summary
    pfam09606
    Location:22562640
    Med15; ARC105 or Med15 subunit of Mediator complex non-fungal
    pfam07001
    Location:1160
    BAT2_N; BAT2 N-terminus
  16. XM_006711238.4XP_006711301.1  protein PRRC2C isoform X5

    See identical proteins and their annotated locations for XP_006711301.1

    UniProtKB/Swiss-Prot
    Q9Y520
    Conserved Domains (1) summary
    pfam07001
    Location:1160
    BAT2_N; BAT2 N-terminus
  17. XM_017000760.2XP_016856249.1  protein PRRC2C isoform X6

RNA

  1. XR_001737059.1 RNA Sequence

  2. XR_001737060.1 RNA Sequence

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