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PHLDB1 pleckstrin homology like domain family B member 1 [ Homo sapiens (human) ]

Gene ID: 23187, updated on 7-Oct-2018

Summary

Official Symbol
PHLDB1provided by HGNC
Official Full Name
pleckstrin homology like domain family B member 1provided by HGNC
Primary source
HGNC:HGNC:23697
See related
Ensembl:ENSG00000019144 MIM:612834; Vega:OTTHUMG00000166341
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
LL5A
Expression
Ubiquitous expression in fat (RPKM 23.2), brain (RPKM 15.4) and 23 other tissues See more
Orthologs

Genomic context

See PHLDB1 in Genome Data Viewer
Location:
11q23.3
Exon count:
34
Annotation release Status Assembly Chr Location
109 current GRCh38.p12 (GCF_000001405.38) 11 NC_000011.10 (118606296..118658038)
105 previous assembly GRCh37.p13 (GCF_000001405.25) 11 NC_000011.9 (118477213..118528748)

Chromosome 11 - NC_000011.10Genomic Context describing neighboring genes Neighboring gene intraflagellar transport 46 Neighboring gene ribosomal protein L5 pseudogene 30 Neighboring gene archain 1 Neighboring gene RNA, U6 small nuclear 1157, pseudogene Neighboring gene microRNA 6716 Neighboring gene trehalase Neighboring gene trehalase pseudogene 1

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Jun 15 11:32:44 2016

Bibliography

GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

Phenotypes

NHGRI GWAS Catalog

Description
Association analyses identify three susceptibility Loci for vitiligo in the Chinese Han population.
NHGRI GWA Catalog
Chromosome 7p11.2 (EGFR) variation influences glioma risk.
NHGRI GWA Catalog
Discovery and refinement of loci associated with lipid levels.
NHGRI GWA Catalog
Genome-wide association analyses suggest NELL1 influences adverse metabolic response to HCTZ in African Americans.
NHGRI GWA Catalog
Genome-wide association study identifies five susceptibility loci for glioma.
NHGRI GWA Catalog

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Clone Names

  • FLJ00141, FLJ90266, KIAA0638, MGC111531, DKFZp686H039, DKFZp686O24210

General protein information

Preferred Names
pleckstrin homology-like domain family B member 1
Names
LL5alpha
pleckstrin homology-like domain family B member 1 variant 3
pleckstrin homology-like domain family B member 1 variant 4
protein LL5-alpha

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001144758.2NP_001138230.1  pleckstrin homology-like domain family B member 1 isoform a

    See identical proteins and their annotated locations for NP_001138230.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) represents use of an alternate promoter and differs in the 5' UTR, compared to variant 1. Variants 1 and 2 encode the same isoform (a).
    Source sequence(s)
    AB014538, AI917888, AK074918, AK125783, BX489377
    Consensus CDS
    CCDS8401.1
    UniProtKB/Swiss-Prot
    Q86UU1
    UniProtKB/TrEMBL
    A0A024R3H6, Q6ZUD6, Q8NC75
    Related
    ENSP00000469820.1, ENST00000600882.5
    Conserved Domains (6) summary
    cd14673
    Location:12551370
    PH_PHLDB1_2; Pleckstrin homology-like domain-containing family B member 2 pleckstrin homology (PH) domain
    pfam00169
    Location:12581365
    PH; PH domain
    pfam00498
    Location:64124
    FHA; FHA domain
    pfam14988
    Location:728931
    DUF4515; Domain of unknown function (DUF4515)
    pfam15223
    Location:469552
    DUF4584; Domain of unknown function (DUF4584)
    cl19107
    Location:715812
    SPFH_like; core domain of the SPFH (stomatin, prohibitin, flotillin, and HflK/C) superfamily
  2. NM_001144759.2NP_001138231.1  pleckstrin homology-like domain family B member 1 isoform b

    See identical proteins and their annotated locations for NP_001138231.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (3) represents use of an alternate promoter, differs in the 5' UTR, and lacks two alternate in-frame exons in the coding region, compared to variant 1. The resulting isoform (b) lacks two internal segments, compared to isoform a.
    Source sequence(s)
    AB014538, AI917888, AK074918, AK125783, BX489377
    Consensus CDS
    CCDS44750.1
    UniProtKB/Swiss-Prot
    Q86UU1
    UniProtKB/TrEMBL
    A0A024R3F4, Q6ZUD6, Q8NC75
    Related
    ENSP00000348359.5, OTTHUMP00000233082, ENST00000356063.9, OTTHUMT00000390085
    Conserved Domains (7) summary
    COG1579
    Location:726930
    COG1579; Predicted nucleic acid-binding protein, contains Zn-ribbon domain [General function prediction only]
    cd14673
    Location:12081312
    PH_PHLDB1_2; Pleckstrin homology-like domain-containing family B member 2 pleckstrin homology (PH) domain
    pfam00169
    Location:12111307
    PH; PH domain
    pfam00498
    Location:64124
    FHA; FHA domain
    pfam10473
    Location:676803
    CENP-F_leu_zip; Leucine-rich repeats of kinetochore protein Cenp-F/LEK1
    pfam15223
    Location:469552
    DUF4584; Domain of unknown function (DUF4584)
    cl19107
    Location:715812
    SPFH_like; core domain of the SPFH (stomatin, prohibitin, flotillin, and HflK/C) superfamily
  3. NM_015157.3NP_055972.1  pleckstrin homology-like domain family B member 1 isoform a

    See identical proteins and their annotated locations for NP_055972.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) represents the longest transcript and encodes the longer isoform (a). Variants 1 and 2 encode the same isoform.
    Source sequence(s)
    AB094090, AI917888, AK125783, AP000941
    Consensus CDS
    CCDS8401.1
    UniProtKB/Swiss-Prot
    Q86UU1
    UniProtKB/TrEMBL
    A0A024R3H6, Q6ZUD6
    Related
    ENSP00000354498.2, OTTHUMP00000232681, ENST00000361417.6, OTTHUMT00000389279
    Conserved Domains (6) summary
    cd14673
    Location:12551370
    PH_PHLDB1_2; Pleckstrin homology-like domain-containing family B member 2 pleckstrin homology (PH) domain
    pfam00169
    Location:12581365
    PH; PH domain
    pfam00498
    Location:64124
    FHA; FHA domain
    pfam14988
    Location:728931
    DUF4515; Domain of unknown function (DUF4515)
    pfam15223
    Location:469552
    DUF4584; Domain of unknown function (DUF4584)
    cl19107
    Location:715812
    SPFH_like; core domain of the SPFH (stomatin, prohibitin, flotillin, and HflK/C) superfamily

RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 109 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p12 Primary Assembly

Genomic

  1. NC_000011.10 Reference GRCh38.p12 Primary Assembly

    Range
    118606296..118658038
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_011542709.2XP_011541011.1  pleckstrin homology-like domain family B member 1 isoform X8

    See identical proteins and their annotated locations for XP_011541011.1

    Conserved Domains (7) summary
    cd14673
    Location:14181533
    PH_PHLDB1_2; Pleckstrin homology-like domain-containing family B member 2 pleckstrin homology (PH) domain
    pfam00169
    Location:14211528
    PH; PH domain
    pfam00498
    Location:64124
    FHA; FHA domain
    pfam10473
    Location:676819
    CENP-F_leu_zip; Leucine-rich repeats of kinetochore protein Cenp-F/LEK1
    pfam15223
    Location:469552
    DUF4584; Domain of unknown function (DUF4584)
    cl02488
    Location:739940
    SPEC; Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; ...
    cl19107
    Location:715816
    SPFH_like; core domain of the SPFH (stomatin, prohibitin, flotillin, and HflK/C) superfamily
  2. XM_011542708.3XP_011541010.1  pleckstrin homology-like domain family B member 1 isoform X8

    See identical proteins and their annotated locations for XP_011541010.1

    Conserved Domains (7) summary
    cd14673
    Location:14181533
    PH_PHLDB1_2; Pleckstrin homology-like domain-containing family B member 2 pleckstrin homology (PH) domain
    pfam00169
    Location:14211528
    PH; PH domain
    pfam00498
    Location:64124
    FHA; FHA domain
    pfam10473
    Location:676819
    CENP-F_leu_zip; Leucine-rich repeats of kinetochore protein Cenp-F/LEK1
    pfam15223
    Location:469552
    DUF4584; Domain of unknown function (DUF4584)
    cl02488
    Location:739940
    SPEC; Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; ...
    cl19107
    Location:715816
    SPFH_like; core domain of the SPFH (stomatin, prohibitin, flotillin, and HflK/C) superfamily
  3. XM_006718796.4XP_006718859.1  pleckstrin homology-like domain family B member 1 isoform X9

    Conserved Domains (7) summary
    cd14673
    Location:14171532
    PH_PHLDB1_2; Pleckstrin homology-like domain-containing family B member 2 pleckstrin homology (PH) domain
    pfam00169
    Location:14201527
    PH; PH domain
    pfam00498
    Location:64124
    FHA; FHA domain
    pfam10473
    Location:675818
    CENP-F_leu_zip; Leucine-rich repeats of kinetochore protein Cenp-F/LEK1
    pfam15223
    Location:468551
    DUF4584; Domain of unknown function (DUF4584)
    cl02488
    Location:738939
    SPEC; Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; ...
    cl19107
    Location:714815
    SPFH_like; core domain of the SPFH (stomatin, prohibitin, flotillin, and HflK/C) superfamily
  4. XM_011542703.2XP_011541005.1  pleckstrin homology-like domain family B member 1 isoform X1

    Conserved Domains (6) summary
    cd14673
    Location:14641579
    PH_PHLDB1_2; Pleckstrin homology-like domain-containing family B member 2 pleckstrin homology (PH) domain
    pfam00169
    Location:14671574
    PH; PH domain
    pfam00498
    Location:110170
    FHA; FHA domain
    pfam10473
    Location:722865
    CENP-F_leu_zip; Leucine-rich repeats of kinetochore protein Cenp-F/LEK1
    pfam15223
    Location:515598
    DUF4584; Domain of unknown function (DUF4584)
    cl23750
    Location:785886
    vATP-synt_E; ATP synthase (E/31 kDa) subunit
  5. XM_011542704.2XP_011541006.1  pleckstrin homology-like domain family B member 1 isoform X3

    Conserved Domains (6) summary
    cd14673
    Location:14641568
    PH_PHLDB1_2; Pleckstrin homology-like domain-containing family B member 2 pleckstrin homology (PH) domain
    pfam00169
    Location:14671563
    PH; PH domain
    pfam00498
    Location:110170
    FHA; FHA domain
    pfam10473
    Location:722865
    CENP-F_leu_zip; Leucine-rich repeats of kinetochore protein Cenp-F/LEK1
    pfam15223
    Location:515598
    DUF4584; Domain of unknown function (DUF4584)
    cl23750
    Location:785886
    vATP-synt_E; ATP synthase (E/31 kDa) subunit
  6. XM_011542705.2XP_011541007.1  pleckstrin homology-like domain family B member 1 isoform X4

    Conserved Domains (6) summary
    cd14673
    Location:14491564
    PH_PHLDB1_2; Pleckstrin homology-like domain-containing family B member 2 pleckstrin homology (PH) domain
    pfam00169
    Location:14521559
    PH; PH domain
    pfam00498
    Location:110170
    FHA; FHA domain
    pfam10473
    Location:722865
    CENP-F_leu_zip; Leucine-rich repeats of kinetochore protein Cenp-F/LEK1
    pfam15223
    Location:515598
    DUF4584; Domain of unknown function (DUF4584)
    cl23750
    Location:785886
    vATP-synt_E; ATP synthase (E/31 kDa) subunit
  7. XM_011542706.2XP_011541008.1  pleckstrin homology-like domain family B member 1 isoform X5

    Conserved Domains (6) summary
    cd14673
    Location:14491553
    PH_PHLDB1_2; Pleckstrin homology-like domain-containing family B member 2 pleckstrin homology (PH) domain
    pfam00169
    Location:14521548
    PH; PH domain
    pfam00498
    Location:110170
    FHA; FHA domain
    pfam10473
    Location:722865
    CENP-F_leu_zip; Leucine-rich repeats of kinetochore protein Cenp-F/LEK1
    pfam15223
    Location:515598
    DUF4584; Domain of unknown function (DUF4584)
    cl23750
    Location:785886
    vATP-synt_E; ATP synthase (E/31 kDa) subunit
  8. XM_011542710.2XP_011541012.1  pleckstrin homology-like domain family B member 1 isoform X11

    Conserved Domains (7) summary
    cd14673
    Location:14071522
    PH_PHLDB1_2; Pleckstrin homology-like domain-containing family B member 2 pleckstrin homology (PH) domain
    pfam00169
    Location:14101517
    PH; PH domain
    pfam00498
    Location:110170
    FHA; FHA domain
    pfam10473
    Location:722865
    CENP-F_leu_zip; Leucine-rich repeats of kinetochore protein Cenp-F/LEK1
    pfam15223
    Location:515598
    DUF4584; Domain of unknown function (DUF4584)
    cl02488
    Location:785986
    SPEC; Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; ...
    cl19107
    Location:761862
    SPFH_like; core domain of the SPFH (stomatin, prohibitin, flotillin, and HflK/C) superfamily
  9. XM_017017409.1XP_016872898.1  pleckstrin homology-like domain family B member 1 isoform X13

  10. XM_006718797.3XP_006718860.1  pleckstrin homology-like domain family B member 1 isoform X10

    Conserved Domains (7) summary
    cd14673
    Location:14161531
    PH_PHLDB1_2; Pleckstrin homology-like domain-containing family B member 2 pleckstrin homology (PH) domain
    pfam00169
    Location:14191526
    PH; PH domain
    pfam00498
    Location:110170
    FHA; FHA domain
    pfam10473
    Location:722865
    CENP-F_leu_zip; Leucine-rich repeats of kinetochore protein Cenp-F/LEK1
    pfam15223
    Location:515598
    DUF4584; Domain of unknown function (DUF4584)
    cl02488
    Location:785986
    SPEC; Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; ...
    cl19107
    Location:761862
    SPFH_like; core domain of the SPFH (stomatin, prohibitin, flotillin, and HflK/C) superfamily
  11. XM_017017408.1XP_016872897.1  pleckstrin homology-like domain family B member 1 isoform X12

  12. XM_006718798.3XP_006718861.1  pleckstrin homology-like domain family B member 1 isoform X15

    Conserved Domains (7) summary
    cd14673
    Location:13591474
    PH_PHLDB1_2; Pleckstrin homology-like domain-containing family B member 2 pleckstrin homology (PH) domain
    pfam00169
    Location:13621469
    PH; PH domain
    pfam00498
    Location:110170
    FHA; FHA domain
    pfam10473
    Location:722865
    CENP-F_leu_zip; Leucine-rich repeats of kinetochore protein Cenp-F/LEK1
    pfam15223
    Location:515598
    DUF4584; Domain of unknown function (DUF4584)
    cl02488
    Location:785986
    SPEC; Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; ...
    cl19107
    Location:761862
    SPFH_like; core domain of the SPFH (stomatin, prohibitin, flotillin, and HflK/C) superfamily
  13. XM_006718799.3XP_006718862.1  pleckstrin homology-like domain family B member 1 isoform X16

    Conserved Domains (7) summary
    cd14673
    Location:13441459
    PH_PHLDB1_2; Pleckstrin homology-like domain-containing family B member 2 pleckstrin homology (PH) domain
    pfam00169
    Location:13471454
    PH; PH domain
    pfam00498
    Location:110170
    FHA; FHA domain
    pfam10473
    Location:722865
    CENP-F_leu_zip; Leucine-rich repeats of kinetochore protein Cenp-F/LEK1
    pfam15223
    Location:515598
    DUF4584; Domain of unknown function (DUF4584)
    cl02488
    Location:785986
    SPEC; Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; ...
    cl19107
    Location:761862
    SPFH_like; core domain of the SPFH (stomatin, prohibitin, flotillin, and HflK/C) superfamily
  14. XM_006718800.3XP_006718863.1  pleckstrin homology-like domain family B member 1 isoform X17

    Conserved Domains (7) summary
    cd14673
    Location:13441448
    PH_PHLDB1_2; Pleckstrin homology-like domain-containing family B member 2 pleckstrin homology (PH) domain
    pfam00169
    Location:13471443
    PH; PH domain
    pfam00498
    Location:110170
    FHA; FHA domain
    pfam10473
    Location:722865
    CENP-F_leu_zip; Leucine-rich repeats of kinetochore protein Cenp-F/LEK1
    pfam15223
    Location:515598
    DUF4584; Domain of unknown function (DUF4584)
    cl02488
    Location:785986
    SPEC; Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; ...
    cl19107
    Location:761862
    SPFH_like; core domain of the SPFH (stomatin, prohibitin, flotillin, and HflK/C) superfamily
  15. XM_006718801.3XP_006718864.1  pleckstrin homology-like domain family B member 1 isoform X19

    Conserved Domains (7) summary
    cd14673
    Location:13121427
    PH_PHLDB1_2; Pleckstrin homology-like domain-containing family B member 2 pleckstrin homology (PH) domain
    pfam00169
    Location:13151422
    PH; PH domain
    pfam00498
    Location:110170
    FHA; FHA domain
    pfam10473
    Location:722865
    CENP-F_leu_zip; Leucine-rich repeats of kinetochore protein Cenp-F/LEK1
    pfam15223
    Location:515598
    DUF4584; Domain of unknown function (DUF4584)
    cl02488
    Location:785986
    SPEC; Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; ...
    cl19107
    Location:761862
    SPFH_like; core domain of the SPFH (stomatin, prohibitin, flotillin, and HflK/C) superfamily
  16. XM_006718802.3XP_006718865.1  pleckstrin homology-like domain family B member 1 isoform X23

    Conserved Domains (7) summary
    cd14673
    Location:12971412
    PH_PHLDB1_2; Pleckstrin homology-like domain-containing family B member 2 pleckstrin homology (PH) domain
    pfam00169
    Location:13001407
    PH; PH domain
    pfam00498
    Location:110170
    FHA; FHA domain
    pfam10473
    Location:722865
    CENP-F_leu_zip; Leucine-rich repeats of kinetochore protein Cenp-F/LEK1
    pfam15223
    Location:515598
    DUF4584; Domain of unknown function (DUF4584)
    cl02488
    Location:785986
    SPEC; Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; ...
    cl19107
    Location:761862
    SPFH_like; core domain of the SPFH (stomatin, prohibitin, flotillin, and HflK/C) superfamily
  17. XM_006718803.3XP_006718866.1  pleckstrin homology-like domain family B member 1 isoform X26

    Conserved Domains (7) summary
    cd14673
    Location:12971401
    PH_PHLDB1_2; Pleckstrin homology-like domain-containing family B member 2 pleckstrin homology (PH) domain
    pfam00169
    Location:13001396
    PH; PH domain
    pfam00498
    Location:110170
    FHA; FHA domain
    pfam10473
    Location:722865
    CENP-F_leu_zip; Leucine-rich repeats of kinetochore protein Cenp-F/LEK1
    pfam15223
    Location:515598
    DUF4584; Domain of unknown function (DUF4584)
    cl02488
    Location:785986
    SPEC; Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; ...
    cl19107
    Location:761862
    SPFH_like; core domain of the SPFH (stomatin, prohibitin, flotillin, and HflK/C) superfamily
  18. XM_011542707.2XP_011541009.1  pleckstrin homology-like domain family B member 1 isoform X6

    Conserved Domains (8) summary
    cd14673
    Location:14211536
    PH_PHLDB1_2; Pleckstrin homology-like domain-containing family B member 2 pleckstrin homology (PH) domain
    pfam00169
    Location:14241531
    PH; PH domain
    pfam00498
    Location:110170
    FHA; FHA domain
    pfam10473
    Location:722849
    CENP-F_leu_zip; Leucine-rich repeats of kinetochore protein Cenp-F/LEK1
    pfam15223
    Location:515598
    DUF4584; Domain of unknown function (DUF4584)
    cd16269
    Location:819832
    GBP_C; coiled coil [structural motif]
    cl02488
    Location:758943
    SPEC; Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; ...
    cl20817
    Location:760847
    GBP_C; Guanylate-binding protein, C-terminal domain
  19. XM_017017410.1XP_016872899.1  pleckstrin homology-like domain family B member 1 isoform X14

  20. XM_005271468.3XP_005271525.1  pleckstrin homology-like domain family B member 1 isoform X18

    Conserved Domains (6) summary
    cd14673
    Location:13161431
    PH_PHLDB1_2; Pleckstrin homology-like domain-containing family B member 2 pleckstrin homology (PH) domain
    pfam00169
    Location:13191426
    PH; PH domain
    pfam00498
    Location:110170
    FHA; FHA domain
    pfam14988
    Location:774977
    DUF4515; Domain of unknown function (DUF4515)
    pfam15223
    Location:515598
    DUF4584; Domain of unknown function (DUF4584)
    cl19107
    Location:761858
    SPFH_like; core domain of the SPFH (stomatin, prohibitin, flotillin, and HflK/C) superfamily
  21. XM_005271469.3XP_005271526.1  pleckstrin homology-like domain family B member 1 isoform X20

    Conserved Domains (6) summary
    cd14673
    Location:13161420
    PH_PHLDB1_2; Pleckstrin homology-like domain-containing family B member 2 pleckstrin homology (PH) domain
    pfam00169
    Location:13191415
    PH; PH domain
    pfam00498
    Location:110170
    FHA; FHA domain
    pfam14988
    Location:774977
    DUF4515; Domain of unknown function (DUF4515)
    pfam15223
    Location:515598
    DUF4584; Domain of unknown function (DUF4584)
    cl19107
    Location:761858
    SPFH_like; core domain of the SPFH (stomatin, prohibitin, flotillin, and HflK/C) superfamily
  22. XM_005271470.3XP_005271527.1  pleckstrin homology-like domain family B member 1 isoform X21

    Conserved Domains (6) summary
    cd14673
    Location:13011416
    PH_PHLDB1_2; Pleckstrin homology-like domain-containing family B member 2 pleckstrin homology (PH) domain
    pfam00169
    Location:13041411
    PH; PH domain
    pfam00498
    Location:110170
    FHA; FHA domain
    pfam14988
    Location:774977
    DUF4515; Domain of unknown function (DUF4515)
    pfam15223
    Location:515598
    DUF4584; Domain of unknown function (DUF4584)
    cl19107
    Location:761858
    SPFH_like; core domain of the SPFH (stomatin, prohibitin, flotillin, and HflK/C) superfamily
  23. XM_005271471.3XP_005271528.1  pleckstrin homology-like domain family B member 1 isoform X25

    Conserved Domains (6) summary
    cd14673
    Location:13011405
    PH_PHLDB1_2; Pleckstrin homology-like domain-containing family B member 2 pleckstrin homology (PH) domain
    pfam00169
    Location:13041400
    PH; PH domain
    pfam00498
    Location:110170
    FHA; FHA domain
    pfam14988
    Location:774977
    DUF4515; Domain of unknown function (DUF4515)
    pfam15223
    Location:515598
    DUF4584; Domain of unknown function (DUF4584)
    cl19107
    Location:761858
    SPFH_like; core domain of the SPFH (stomatin, prohibitin, flotillin, and HflK/C) superfamily
  24. XM_005271472.3XP_005271529.1  pleckstrin homology-like domain family B member 1 isoform X27

    Conserved Domains (7) summary
    COG1579
    Location:772976
    COG1579; Predicted nucleic acid-binding protein, contains Zn-ribbon domain [General function prediction only]
    cd14673
    Location:12691384
    PH_PHLDB1_2; Pleckstrin homology-like domain-containing family B member 2 pleckstrin homology (PH) domain
    pfam00169
    Location:12721379
    PH; PH domain
    pfam00498
    Location:110170
    FHA; FHA domain
    pfam10473
    Location:722849
    CENP-F_leu_zip; Leucine-rich repeats of kinetochore protein Cenp-F/LEK1
    pfam15223
    Location:515598
    DUF4584; Domain of unknown function (DUF4584)
    cl19107
    Location:761858
    SPFH_like; core domain of the SPFH (stomatin, prohibitin, flotillin, and HflK/C) superfamily
  25. XM_005271473.3XP_005271530.1  pleckstrin homology-like domain family B member 1 isoform X28

    Conserved Domains (7) summary
    COG1579
    Location:772976
    COG1579; Predicted nucleic acid-binding protein, contains Zn-ribbon domain [General function prediction only]
    cd14673
    Location:12541369
    PH_PHLDB1_2; Pleckstrin homology-like domain-containing family B member 2 pleckstrin homology (PH) domain
    pfam00169
    Location:12571364
    PH; PH domain
    pfam00498
    Location:110170
    FHA; FHA domain
    pfam10473
    Location:722849
    CENP-F_leu_zip; Leucine-rich repeats of kinetochore protein Cenp-F/LEK1
    pfam15223
    Location:515598
    DUF4584; Domain of unknown function (DUF4584)
    cl19107
    Location:761858
    SPFH_like; core domain of the SPFH (stomatin, prohibitin, flotillin, and HflK/C) superfamily
  26. XM_005277680.3XP_005277737.1  pleckstrin homology-like domain family B member 1 isoform X2

    Conserved Domains (6) summary
    cd14673
    Location:14631578
    PH_PHLDB1_2; Pleckstrin homology-like domain-containing family B member 2 pleckstrin homology (PH) domain
    pfam00169
    Location:14661573
    PH; PH domain
    pfam00498
    Location:110170
    FHA; FHA domain
    pfam10473
    Location:721864
    CENP-F_leu_zip; Leucine-rich repeats of kinetochore protein Cenp-F/LEK1
    pfam15223
    Location:514597
    DUF4584; Domain of unknown function (DUF4584)
    cl23750
    Location:784885
    vATP-synt_E; ATP synthase (E/31 kDa) subunit
  27. XM_017017407.1XP_016872896.1  pleckstrin homology-like domain family B member 1 isoform X7

  28. XM_005271475.3XP_005271532.1  pleckstrin homology-like domain family B member 1 isoform X30

    Conserved Domains (2) summary
    pfam00498
    Location:110170
    FHA; FHA domain
    pfam13863
    Location:760840
    DUF4200; Domain of unknown function (DUF4200)
  29. XM_017017411.1XP_016872900.1  pleckstrin homology-like domain family B member 1 isoform X30

    Conserved Domains (2) summary
    pfam00498
    Location:110170
    FHA; FHA domain
    pfam13863
    Location:760840
    DUF4200; Domain of unknown function (DUF4200)
  30. XM_011542714.2XP_011541016.1  pleckstrin homology-like domain family B member 1 isoform X31

    Conserved Domains (2) summary
    pfam00498
    Location:110170
    FHA; FHA domain
    pfam13863
    Location:760839
    DUF4200; Domain of unknown function (DUF4200)
  31. XM_005271474.5XP_005271531.2  pleckstrin homology-like domain family B member 1 isoform X29

    Conserved Domains (6) summary
    cd14673
    Location:12301334
    PH_PHLDB1_2; Pleckstrin homology-like domain-containing family B member 2 pleckstrin homology (PH) domain
    pfam00498
    Location:86146
    FHA; FHA domain
    pfam03528
    Location:686831
    Rabaptin
    cl25545
    Location:10011039
    V-ATPase_G_2; Vacuolar (H+)-ATPase G subunit
    cl25732
    Location:729937
    SMC_N; RecF/RecN/SMC N terminal domain
    cl28033
    Location:174568
    Herpes_ICP4_C; Herpesvirus ICP4-like protein C-terminal region
  32. XM_011542711.2XP_011541013.1  pleckstrin homology-like domain family B member 1 isoform X22

    See identical proteins and their annotated locations for XP_011541013.1

    Conserved Domains (6) summary
    cd14673
    Location:12981413
    PH_PHLDB1_2; Pleckstrin homology-like domain-containing family B member 2 pleckstrin homology (PH) domain
    pfam00169
    Location:13011408
    PH; PH domain
    pfam10473
    Location:556699
    CENP-F_leu_zip; Leucine-rich repeats of kinetochore protein Cenp-F/LEK1
    pfam15223
    Location:349432
    DUF4584; Domain of unknown function (DUF4584)
    cl02488
    Location:619820
    SPEC; Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; ...
    cl19107
    Location:595696
    SPFH_like; core domain of the SPFH (stomatin, prohibitin, flotillin, and HflK/C) superfamily
  33. XM_011542713.2XP_011541015.1  pleckstrin homology-like domain family B member 1 isoform X24

    Conserved Domains (6) summary
    cd14673
    Location:12971412
    PH_PHLDB1_2; Pleckstrin homology-like domain-containing family B member 2 pleckstrin homology (PH) domain
    pfam00169
    Location:13001407
    PH; PH domain
    pfam10473
    Location:555698
    CENP-F_leu_zip; Leucine-rich repeats of kinetochore protein Cenp-F/LEK1
    pfam15223
    Location:348431
    DUF4584; Domain of unknown function (DUF4584)
    cl02488
    Location:618819
    SPEC; Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; ...
    cl19107
    Location:594695
    SPFH_like; core domain of the SPFH (stomatin, prohibitin, flotillin, and HflK/C) superfamily
  34. XM_011542715.3XP_011541017.1  pleckstrin homology-like domain family B member 1 isoform X32

    Conserved Domains (3) summary
    cd14673
    Location:610714
    PH_PHLDB1_2; Pleckstrin homology-like domain-containing family B member 2 pleckstrin homology (PH) domain
    pfam00169
    Location:613709
    PH; PH domain
    cl19107
    Location:117214
    SPFH_like; core domain of the SPFH (stomatin, prohibitin, flotillin, and HflK/C) superfamily

RNA

  1. XR_001747797.1 RNA Sequence

  2. XR_947813.2 RNA Sequence

  3. XR_001747798.1 RNA Sequence

  4. XR_001747799.1 RNA Sequence

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