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Tnrc18 trinucleotide repeat containing 18 [ Mus musculus (house mouse) ]

Gene ID: 231861, updated on 5-Mar-2024

Summary

Official Symbol
Tnrc18provided by MGI
Official Full Name
trinucleotide repeat containing 18provided by MGI
Primary source
MGI:MGI:3648294
See related
Ensembl:ENSMUSG00000039477 AllianceGenome:MGI:3648294
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Zfp469; EG381742
Summary
Predicted to enable chromatin binding activity. Predicted to be located in cytosol; mitochondrion; and nucleus. Orthologous to human TNRC18 (trinucleotide repeat containing 18). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Ubiquitous expression in ovary adult (RPKM 24.2), colon adult (RPKM 14.8) and 25 other tissues See more
Orthologs
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Genomic context

See Tnrc18 in Genome Data Viewer
Location:
5 G2; 5 81.73 cM
Exon count:
34
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 5 NC_000071.7 (142710357..142812386, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 5 NC_000071.6 (142724602..142823668, complement)

Chromosome 5 - NC_000071.7Genomic Context describing neighboring genes Neighboring gene STARR-positive B cell enhancer ABC_E10363 Neighboring gene WD repeat domain, phosphoinositide interacting 2 Neighboring gene STARR-seq mESC enhancer starr_14752 Neighboring gene predicted gene, 40352 Neighboring gene solute carrier family 29 (nucleoside transporters), member 4 Neighboring gene STARR-seq mESC enhancer starr_14754 Neighboring gene STARR-seq mESC enhancer starr_14759 Neighboring gene STARR-seq mESC enhancer starr_14762 Neighboring gene predicted gene, 31365 Neighboring gene predicted gene 15770 Neighboring gene predicted gene, 52793

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Clone Names

  • MGC59613

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables chromatin binding IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
located_in cytosol ISO
Inferred from Sequence Orthology
more info
 
located_in mitochondrion ISO
Inferred from Sequence Orthology
more info
 
located_in nuclear membrane ISO
Inferred from Sequence Orthology
more info
 
located_in nucleoplasm ISO
Inferred from Sequence Orthology
more info
 

General protein information

Preferred Names
trinucleotide repeat-containing gene 18 protein

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001122730.3NP_001116202.2  trinucleotide repeat-containing gene 18 protein isoform A

    Status: VALIDATED

    Description
    Transcript Variant: This variant (A) represents the longer transcript and encodes the longer isoform (A).
    Source sequence(s)
    AC144818, AC240265, AK141849, AW491486, BC049818, BC094365, BY713750, CB244319, CB249572
    UniProtKB/Swiss-Prot
    Q1LZJ7, Q69Z86, Q80WC3
    Related
    ENSMUSP00000117651.3, ENSMUST00000152247.8
    Conserved Domains (4) summary
    PHA03247
    Location:9961305
    PHA03247; large tegument protein UL36; Provisional
    PRK12323
    Location:21692383
    PRK12323; DNA polymerase III subunit gamma/tau
    cd04714
    Location:27032847
    BAH_BAHCC1; BAH, or Bromo Adjacent Homology domain, as present in mammalian BAHCC1 and similar proteins. BAHCC1 stands for BAH domain and coiled-coil containing 1. BAH domains are found in a variety of proteins playing roles in transcriptional silencing and the ...
    cl02573
    Location:21082174
    Tudor_SF; Tudor domain superfamily
  2. NM_178242.3NP_839973.1  trinucleotide repeat-containing gene 18 protein isoform B

    See identical proteins and their annotated locations for NP_839973.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (B) contains an alternate in-frame exon and differs in the 3' UTR and coding sequence compared to variant A. The resulting isoform (B) contains an alternate internal segment and has a shorter and distinct C-terminus compared to isoform A.
    Source sequence(s)
    AC144818, BC049818, BY713750, CB520310
    Consensus CDS
    CCDS19830.1
    UniProtKB/TrEMBL
    D3YV17
    Related
    ENSMUSP00000114769.3, ENSMUST00000151477.8

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000071.7 Reference GRCm39 C57BL/6J

    Range
    142710357..142812386 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_030254452.2XP_030110312.1  trinucleotide repeat-containing gene 18 protein isoform X4

    UniProtKB/Swiss-Prot
    Q1LZJ7, Q69Z86, Q80WC3
    Conserved Domains (4) summary
    PHA03247
    Location:9971306
    PHA03247; large tegument protein UL36; Provisional
    PRK12323
    Location:22132427
    PRK12323; DNA polymerase III subunit gamma/tau
    cd04714
    Location:27472891
    BAH_BAHCC1; BAH, or Bromo Adjacent Homology domain, as present in mammalian BAHCC1 and similar proteins. BAHCC1 stands for BAH domain and coiled-coil containing 1. BAH domains are found in a variety of proteins playing roles in transcriptional silencing and the ...
    cl02573
    Location:21522218
    Tudor_SF; Tudor domain superfamily
  2. XM_011240976.4XP_011239278.1  trinucleotide repeat-containing gene 18 protein isoform X1

    See identical proteins and their annotated locations for XP_011239278.1

    UniProtKB/Swiss-Prot
    Q1LZJ7, Q69Z86, Q80WC3
    Conserved Domains (4) summary
    PHA03247
    Location:10491358
    PHA03247; large tegument protein UL36; Provisional
    PRK12323
    Location:22652479
    PRK12323; DNA polymerase III subunit gamma/tau
    cd04714
    Location:27992943
    BAH_BAHCC1; BAH, or Bromo Adjacent Homology domain, as present in mammalian BAHCC1 and similar proteins. BAHCC1 stands for BAH domain and coiled-coil containing 1. BAH domains are found in a variety of proteins playing roles in transcriptional silencing and the ...
    cl07283
    Location:22122264
    Tudor_3; DNA repair protein Crb2 Tudor domain
  3. XM_036165101.1XP_036020994.1  trinucleotide repeat-containing gene 18 protein isoform X4

    UniProtKB/Swiss-Prot
    Q1LZJ7, Q69Z86, Q80WC3
    Conserved Domains (4) summary
    PHA03247
    Location:9971306
    PHA03247; large tegument protein UL36; Provisional
    PRK12323
    Location:22132427
    PRK12323; DNA polymerase III subunit gamma/tau
    cd04714
    Location:27472891
    BAH_BAHCC1; BAH, or Bromo Adjacent Homology domain, as present in mammalian BAHCC1 and similar proteins. BAHCC1 stands for BAH domain and coiled-coil containing 1. BAH domains are found in a variety of proteins playing roles in transcriptional silencing and the ...
    cl02573
    Location:21522218
    Tudor_SF; Tudor domain superfamily
  4. XM_011240977.4XP_011239279.1  trinucleotide repeat-containing gene 18 protein isoform X1

    See identical proteins and their annotated locations for XP_011239279.1

    UniProtKB/Swiss-Prot
    Q1LZJ7, Q69Z86, Q80WC3
    Conserved Domains (4) summary
    PHA03247
    Location:10491358
    PHA03247; large tegument protein UL36; Provisional
    PRK12323
    Location:22652479
    PRK12323; DNA polymerase III subunit gamma/tau
    cd04714
    Location:27992943
    BAH_BAHCC1; BAH, or Bromo Adjacent Homology domain, as present in mammalian BAHCC1 and similar proteins. BAHCC1 stands for BAH domain and coiled-coil containing 1. BAH domains are found in a variety of proteins playing roles in transcriptional silencing and the ...
    cl07283
    Location:22122264
    Tudor_3; DNA repair protein Crb2 Tudor domain
  5. XM_030254454.2XP_030110314.1  trinucleotide repeat-containing gene 18 protein isoform X5

    UniProtKB/Swiss-Prot
    Q1LZJ7, Q69Z86, Q80WC3
    Conserved Domains (4) summary
    PHA03247
    Location:9961305
    PHA03247; large tegument protein UL36; Provisional
    PRK12323
    Location:22122426
    PRK12323; DNA polymerase III subunit gamma/tau
    cd04714
    Location:27462890
    BAH_BAHCC1; BAH, or Bromo Adjacent Homology domain, as present in mammalian BAHCC1 and similar proteins. BAHCC1 stands for BAH domain and coiled-coil containing 1. BAH domains are found in a variety of proteins playing roles in transcriptional silencing and the ...
    cl07283
    Location:21592211
    Tudor_3; DNA repair protein Crb2 Tudor domain
  6. XM_006504690.5XP_006504753.1  trinucleotide repeat-containing gene 18 protein isoform X4

    See identical proteins and their annotated locations for XP_006504753.1

    UniProtKB/Swiss-Prot
    Q1LZJ7, Q69Z86, Q80WC3
    Conserved Domains (4) summary
    PHA03247
    Location:9971306
    PHA03247; large tegument protein UL36; Provisional
    PRK12323
    Location:22132427
    PRK12323; DNA polymerase III subunit gamma/tau
    cd04714
    Location:27472891
    BAH_BAHCC1; BAH, or Bromo Adjacent Homology domain, as present in mammalian BAHCC1 and similar proteins. BAHCC1 stands for BAH domain and coiled-coil containing 1. BAH domains are found in a variety of proteins playing roles in transcriptional silencing and the ...
    cl02573
    Location:21522218
    Tudor_SF; Tudor domain superfamily
  7. XM_006504688.4XP_006504751.1  trinucleotide repeat-containing gene 18 protein isoform X2

    UniProtKB/Swiss-Prot
    Q1LZJ7, Q69Z86, Q80WC3
    Conserved Domains (4) summary
    PHA03247
    Location:10481357
    PHA03247; large tegument protein UL36; Provisional
    PRK12323
    Location:22642478
    PRK12323; DNA polymerase III subunit gamma/tau
    cd04714
    Location:27982942
    BAH_BAHCC1; BAH, or Bromo Adjacent Homology domain, as present in mammalian BAHCC1 and similar proteins. BAHCC1 stands for BAH domain and coiled-coil containing 1. BAH domains are found in a variety of proteins playing roles in transcriptional silencing and the ...
    cl07283
    Location:22112263
    Tudor_3; DNA repair protein Crb2 Tudor domain
  8. XM_006504689.4XP_006504752.1  trinucleotide repeat-containing gene 18 protein isoform X3

    UniProtKB/Swiss-Prot
    Q1LZJ7, Q69Z86, Q80WC3
    Conserved Domains (4) summary
    PHA03247
    Location:10491358
    PHA03247; large tegument protein UL36; Provisional
    PRK12323
    Location:22222436
    PRK12323; DNA polymerase III subunit gamma/tau
    cd04714
    Location:27562900
    BAH_BAHCC1; BAH, or Bromo Adjacent Homology domain, as present in mammalian BAHCC1 and similar proteins. BAHCC1 stands for BAH domain and coiled-coil containing 1. BAH domains are found in a variety of proteins playing roles in transcriptional silencing and the ...
    cl07283
    Location:21692221
    Tudor_3; DNA repair protein Crb2 Tudor domain
  9. XM_006504687.4XP_006504750.1  trinucleotide repeat-containing gene 18 protein isoform X1

    See identical proteins and their annotated locations for XP_006504750.1

    UniProtKB/Swiss-Prot
    Q1LZJ7, Q69Z86, Q80WC3
    Conserved Domains (4) summary
    PHA03247
    Location:10491358
    PHA03247; large tegument protein UL36; Provisional
    PRK12323
    Location:22652479
    PRK12323; DNA polymerase III subunit gamma/tau
    cd04714
    Location:27992943
    BAH_BAHCC1; BAH, or Bromo Adjacent Homology domain, as present in mammalian BAHCC1 and similar proteins. BAHCC1 stands for BAH domain and coiled-coil containing 1. BAH domains are found in a variety of proteins playing roles in transcriptional silencing and the ...
    cl07283
    Location:22122264
    Tudor_3; DNA repair protein Crb2 Tudor domain
  10. XM_030254453.2XP_030110313.1  trinucleotide repeat-containing gene 18 protein isoform X4

    UniProtKB/Swiss-Prot
    Q1LZJ7, Q69Z86, Q80WC3
    Conserved Domains (4) summary
    PHA03247
    Location:9971306
    PHA03247; large tegument protein UL36; Provisional
    PRK12323
    Location:22132427
    PRK12323; DNA polymerase III subunit gamma/tau
    cd04714
    Location:27472891
    BAH_BAHCC1; BAH, or Bromo Adjacent Homology domain, as present in mammalian BAHCC1 and similar proteins. BAHCC1 stands for BAH domain and coiled-coil containing 1. BAH domains are found in a variety of proteins playing roles in transcriptional silencing and the ...
    cl02573
    Location:21522218
    Tudor_SF; Tudor domain superfamily
  11. XM_030254451.2XP_030110311.1  trinucleotide repeat-containing gene 18 protein isoform X4

    UniProtKB/Swiss-Prot
    Q1LZJ7, Q69Z86, Q80WC3
    Conserved Domains (4) summary
    PHA03247
    Location:9971306
    PHA03247; large tegument protein UL36; Provisional
    PRK12323
    Location:22132427
    PRK12323; DNA polymerase III subunit gamma/tau
    cd04714
    Location:27472891
    BAH_BAHCC1; BAH, or Bromo Adjacent Homology domain, as present in mammalian BAHCC1 and similar proteins. BAHCC1 stands for BAH domain and coiled-coil containing 1. BAH domains are found in a variety of proteins playing roles in transcriptional silencing and the ...
    cl02573
    Location:21522218
    Tudor_SF; Tudor domain superfamily
  12. XM_006504691.5XP_006504754.1  trinucleotide repeat-containing gene 18 protein isoform X6

    UniProtKB/Swiss-Prot
    Q1LZJ7, Q69Z86, Q80WC3
    Conserved Domains (4) summary
    PHA03247
    Location:9751284
    PHA03247; large tegument protein UL36; Provisional
    PRK12323
    Location:21912405
    PRK12323; DNA polymerase III subunit gamma/tau
    cd04714
    Location:27252869
    BAH_BAHCC1; BAH, or Bromo Adjacent Homology domain, as present in mammalian BAHCC1 and similar proteins. BAHCC1 stands for BAH domain and coiled-coil containing 1. BAH domains are found in a variety of proteins playing roles in transcriptional silencing and the ...
    cl07283
    Location:21382190
    Tudor_3; DNA repair protein Crb2 Tudor domain
  13. XM_030254457.2XP_030110317.1  trinucleotide repeat-containing gene 18 protein isoform X7

    UniProtKB/TrEMBL
    F6Z7L1
    Conserved Domains (4) summary
    PHA03247
    Location:545854
    PHA03247; large tegument protein UL36; Provisional
    PRK12323
    Location:17611975
    PRK12323; DNA polymerase III subunit gamma/tau
    cd04714
    Location:22952439
    BAH_BAHCC1; BAH, or Bromo Adjacent Homology domain, as present in mammalian BAHCC1 and similar proteins. BAHCC1 stands for BAH domain and coiled-coil containing 1. BAH domains are found in a variety of proteins playing roles in transcriptional silencing and the ...
    cl07283
    Location:17081760
    Tudor_3; DNA repair protein Crb2 Tudor domain
  14. XM_036165102.1XP_036020995.1  trinucleotide repeat-containing gene 18 protein isoform X8

    Conserved Domains (1) summary
    NF033930
    Location:10351111
    pneumo_PspA; pneumococcal surface protein A