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ZCCHC14 zinc finger CCHC-type containing 14 [ Homo sapiens (human) ]

Gene ID: 23174, updated on 14-Aug-2022

Summary

Official Symbol
ZCCHC14provided by HGNC
Official Full Name
zinc finger CCHC-type containing 14provided by HGNC
Primary source
HGNC:HGNC:24134
See related
Ensembl:ENSG00000140948 AllianceGenome:HGNC:24134
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
BDG29; BDG-29
Summary
Predicted to enable nucleic acid binding activity; phosphatidylinositol binding activity; and zinc ion binding activity. [provided by Alliance of Genome Resources, Apr 2022]
Expression
Broad expression in testis (RPKM 26.9), ovary (RPKM 7.6) and 24 other tissues See more
Orthologs
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Genomic context

See ZCCHC14 in Genome Data Viewer
Location:
16q24.2
Exon count:
14
Annotation release Status Assembly Chr Location
110 current GRCh38.p14 (GCF_000001405.40) 16 NC_000016.10 (87406248..87493024, complement)
110 current T2T-CHM13v2.0 (GCF_009914755.1) 16 NC_060940.1 (93477131..93563941, complement)
105.20220307 previous assembly GRCh37.p13 (GCF_000001405.25) 16 NC_000016.9 (87439854..87526630, complement)

Chromosome 16 - NC_000016.10Genomic Context describing neighboring genes Neighboring gene F-box protein 31 Neighboring gene uncharacterized LOC124903747 Neighboring gene tRNA-Met (anticodon CAT) 6-1 Neighboring gene microtubule associated protein 1 light chain 3 beta Neighboring gene nuclear receptor subfamily 3 group C member 1 pseudogene 1 Neighboring gene ZCCHC14 divergent transcript Neighboring gene uncharacterized LOC124903748

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

HIV-1 interactions

Replication interactions

Interaction Pubs
Knockdown of zinc finger, CCHC domain containing 14 (ZCCHC14) by shRNA library screening inhibits HIV-1 replication in cultured Jurkat T-cells PubMed

Go to the HIV-1, Human Interaction Database

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Clone Names

  • MGC14139, MGC126527

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables nucleic acid binding IEA
Inferred from Electronic Annotation
more info
 
enables phosphatidylinositol binding IEA
Inferred from Electronic Annotation
more info
 
enables protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
enables zinc ion binding IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
zinc finger CCHC domain-containing protein 14
Names
zinc finger, CCHC domain containing 14

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_015144.3NP_055959.2  zinc finger CCHC domain-containing protein 14

    Status: VALIDATED

    Source sequence(s)
    AC010531, AC092720, AC105429
    Consensus CDS
    CCDS10961.1
    UniProtKB/TrEMBL
    A0A590UJW6
    Related
    ENSP00000499622.1, ENST00000671377.2
    Conserved Domains (3) summary
    cd09558
    Location:431495
    SAM_ZCCH14; SAM domain of ZCCH14 subfamily
    pfam00098
    Location:10451060
    zf-CCHC; Zinc knuckle
    cl02563
    Location:256339
    PX_domain; The Phox Homology domain, a phosphoinositide binding module

RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 110 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000016.10 Reference GRCh38.p14 Primary Assembly

    Range
    87406248..87493024 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_005255858.4XP_005255915.3  zinc finger CCHC domain-containing protein 14 isoform X1

  2. XM_017023082.3XP_016878571.1  zinc finger CCHC domain-containing protein 14 isoform X2

    Related
    ENSP00000456499.1, ENST00000561928.1

RNA

  1. XR_243401.4 RNA Sequence

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060940.1 Alternate T2T-CHM13v2.0

    Range
    93477131..93563941 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)