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TBC1D9 TBC1 domain family member 9 [ Homo sapiens (human) ]

Gene ID: 23158, updated on 2-Oct-2018

Summary

Official Symbol
TBC1D9provided by HGNC
Official Full Name
TBC1 domain family member 9provided by HGNC
Primary source
HGNC:HGNC:21710
See related
Ensembl:ENSG00000109436 MIM:618035; Vega:OTTHUMG00000161405
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
MDR1; GRAMD9
Expression
Ubiquitous expression in spleen (RPKM 19.8), brain (RPKM 12.2) and 23 other tissues See more
Orthologs

Genomic context

See TBC1D9 in Genome Data Viewer
Location:
4q31.21
Exon count:
21
Annotation release Status Assembly Chr Location
109 current GRCh38.p12 (GCF_000001405.38) 4 NC_000004.12 (140620782..140756317, complement)
105 previous assembly GRCh37.p13 (GCF_000001405.25) 4 NC_000004.11 (141541936..141677471, complement)

Chromosome 4 - NC_000004.12Genomic Context describing neighboring genes Neighboring gene RNA, 7SL, cytoplasmic 152, pseudogene Neighboring gene uncoupling protein 1 Neighboring gene trinucleotide repeat containing 18 pseudogene 1 Neighboring gene RNY1 pseudogene 14 Neighboring gene ring finger protein 150 Neighboring gene zinc finger protein 330

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Jun 15 11:32:44 2016

Bibliography

GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Clone Names

  • KIAA0882

Gene Ontology Provided by GOA

Function Evidence Code Pubs
GTPase activator activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Rab GTPase binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
calcium ion binding IEA
Inferred from Electronic Annotation
more info
 
protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
Process Evidence Code Pubs
activation of GTPase activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
intracellular protein transport IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Component Evidence Code Pubs
intracellular IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
TBC1 domain family member 9
Names
TBC1 domain family member 9A
TBC1 domain family, member 9 (with GRAM domain)

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_015130.2NP_055945.2  TBC1 domain family member 9

    See identical proteins and their annotated locations for NP_055945.2

    Status: VALIDATED

    Source sequence(s)
    AC108019, AF131785, AI439646, BC038804, BQ308276, CN332501, CN332502
    Consensus CDS
    CCDS47136.1
    UniProtKB/Swiss-Prot
    Q6ZT07
    Related
    ENSP00000411197.2, OTTHUMP00000220169, ENST00000442267.2, OTTHUMT00000364806
    Conserved Domains (3) summary
    smart00164
    Location:512722
    TBC; Domain in Tre-2, BUB2p, and Cdc16p. Probable Rab-GAPs
    cd13354
    Location:304399
    PH-GRAM2_TCB1D9_TCB1D9B; TBC1 domain family members 9 and 9B (TBC1D9 and TBC1D9B) Pleckstrin Homology-Glucosyltransferases, Rab-like GTPase activators and Myotubularins (PH-GRAM) domain, repeat 2
    cd13351
    Location:157255
    PH-GRAM1_TCB1D9_TCB1D9B; TBC1 domain family members 9 and 9B (TBC1D9 and TBC1D9B) Pleckstrin Homology-Glucosyltransferases, Rab-like GTPase activators and Myotubularins (PH-GRAM) domain, repeat 1

RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 109 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p12 Primary Assembly

Genomic

  1. NC_000004.12 Reference GRCh38.p12 Primary Assembly

    Range
    140620782..140756317 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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