U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

SSPOP SCO-spondin, pseudogene [ Homo sapiens (human) ]

Gene ID: 23145, updated on 22-May-2022

Summary

Official Symbol
SSPOPprovided by HGNC
Official Full Name
SCO-spondin, pseudogeneprovided by HGNC
Primary source
HGNC:HGNC:21998
See related
Ensembl:ENSG00000197558 MIM:617356; AllianceGenome:HGNC:21998
Gene type
pseudo
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
SSPO
Summary
Predicted to enable peptidase inhibitor activity. Predicted to be involved in several processes, including cell adhesion; negative regulation of catalytic activity; and regulation of peptidase activity. Predicted to be located in cytoplasm. Predicted to be active in extracellular matrix and extracellular space. [provided by Alliance of Genome Resources, Apr 2022]
Annotation information
Annotation category: suggests misassembly
Expression
Low expression observed in reference dataset See more
Orthologs
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

See SSPOP in Genome Data Viewer
Location:
7q36.1
Exon count:
103
Annotation release Status Assembly Chr Location
110 current GRCh38.p14 (GCF_000001405.40) 7 NC_000007.14 (149776042..149833965)
110 current T2T-CHM13v2.0 (GCF_009914755.1) 7 NC_060931.1 (150957942..151015873)
105.20220307 previous assembly GRCh37.p13 (GCF_000001405.25) 7 NC_000007.13 (149473131..149531054)

Chromosome 7 - NC_000007.14Genomic Context describing neighboring genes Neighboring gene KRAB-A domain containing 1 Neighboring gene uncharacterized LOC124901771 Neighboring gene zinc finger protein 467 Neighboring gene Sharpr-MPRA regulatory region 4172 Neighboring gene zinc finger protein 862 Neighboring gene ATP6V0E2 antisense RNA 1 Neighboring gene ATPase H+ transporting V0 subunit e2

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Other Names

  • SCO protein, thrombospondin domain containing
  • SCO-spondin
  • SCO-spondin homolog (Bos taurus)
  • subcommissural organ spondin

Clone Names

  • FLJ36112, FLJ45737, KIAA2036

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables peptidase inhibitor activity IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
involved_in cell adhesion IEA
Inferred from Electronic Annotation
more info
 
involved_in cell differentiation IEA
Inferred from Electronic Annotation
more info
 
involved_in negative regulation of catalytic activity IEA
Inferred from Electronic Annotation
more info
 
involved_in nervous system development IEA
Inferred from Electronic Annotation
more info
 
involved_in regulation of peptidase activity IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
is_active_in extracellular matrix IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
is_active_in extracellular space IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
located_in extracellular space TAS
Traceable Author Statement
more info
PubMed 
located_in integral component of plasma membrane IEA
Inferred from Electronic Annotation
more info
 
part_of plasma membrane protein complex IEA
Inferred from Electronic Annotation
more info
 

NCBI Reference Sequences (RefSeq)

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

RNA

  1. NR_163594.1 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    AC004877, KF459635, KF459640, KF495712
    Related
    ENST00000378016.5

RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 110 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000007.14 Reference GRCh38.p14 Primary Assembly

    Range
    149776042..149833965
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060931.1 Alternate T2T-CHM13v2.0

    Range
    150957942..151015873
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Suppressed Reference Sequence(s)

The following Reference Sequences have been suppressed. Explain

  1. NM_198455.2: Suppressed sequence

    Description
    NM_198455.2: This RefSeq record was removed by NCBI staff. Contact info@ncbi.nlm.nih.gov for further information.