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RAD54L2 RAD54 like 2 [ Homo sapiens (human) ]

Gene ID: 23132, updated on 13-Mar-2020

Summary

Official Symbol
RAD54L2provided by HGNC
Official Full Name
RAD54 like 2provided by HGNC
Primary source
HGNC:HGNC:29123
See related
Ensembl:ENSG00000164080
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
ARIP4; HSPC325; SRISNF2L
Expression
Ubiquitous expression in testis (RPKM 3.3), spleen (RPKM 2.8) and 25 other tissues See more
Orthologs

Genomic context

See RAD54L2 in Genome Data Viewer
Location:
3p21.2
Exon count:
24
Annotation release Status Assembly Chr Location
109.20200228 current GRCh38.p13 (GCF_000001405.39) 3 NC_000003.12 (51538719..51668660)
105 previous assembly GRCh37.p13 (GCF_000001405.25) 3 NC_000003.11 (51575596..51697634)

Chromosome 3 - NC_000003.12Genomic Context describing neighboring genes Neighboring gene RNA binding motif protein 15B Neighboring gene DDB1 and CUL4 associated factor 1 Neighboring gene uncharacterized LOC105377085 Neighboring gene Sharpr-MPRA regulatory region 62 Neighboring gene RNA, U6atac small nuclear 29, pseudogene Neighboring gene uncharacterized LOC105377086 Neighboring gene testis expressed 264, ER-phagy receptor Neighboring gene RNA, 5S ribosomal pseudogene 132 Neighboring gene glutamate metabotropic receptor 2

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Clone Names

  • FLJ21396, FLJ22400, KIAA0809

Gene Ontology Provided by GOA

Function Evidence Code Pubs
ATP binding IEA
Inferred from Electronic Annotation
more info
 
DNA binding IEA
Inferred from Electronic Annotation
more info
 
DNA helicase activity IEA
Inferred from Electronic Annotation
more info
 
protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
Process Evidence Code Pubs
DNA duplex unwinding IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
nucleus IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
helicase ARIP4
Names
AR interacting protein 4
RAD54-like protein 2
androgen receptor-interacting protein 4
NP_001309182.1
NP_001309185.1
NP_001309186.1
NP_055921.2

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001322253.2NP_001309182.1  helicase ARIP4 isoform a

    Status: VALIDATED

    Source sequence(s)
    AC092037, AC099050, AC113933
    Consensus CDS
    CCDS33765.2
    UniProtKB/Swiss-Prot
    Q9Y4B4
    Conserved Domains (4) summary
    cd00046
    Location:300492
    DEXDc; DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region.
    pfam00176
    Location:274628
    SNF2_N; SNF2 family N-terminal domain
    pfam00271
    Location:720854
    Helicase_C; Helicase conserved C-terminal domain
    pfam15343
    Location:11921278
    DEPP; Decidual protein induced by progesterone family
  2. NM_001322256.2NP_001309185.1  helicase ARIP4 isoform a

    Status: VALIDATED

    Source sequence(s)
    AC092037, AC099050, AC113933
    Consensus CDS
    CCDS33765.2
    UniProtKB/Swiss-Prot
    Q9Y4B4
    Related
    ENSP00000410283.1, ENST00000432863.1
    Conserved Domains (4) summary
    cd00046
    Location:300492
    DEXDc; DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region.
    pfam00176
    Location:274628
    SNF2_N; SNF2 family N-terminal domain
    pfam00271
    Location:720854
    Helicase_C; Helicase conserved C-terminal domain
    pfam15343
    Location:11921278
    DEPP; Decidual protein induced by progesterone family
  3. NM_001322257.1NP_001309186.1  helicase ARIP4 isoform b

    Status: VALIDATED

    Source sequence(s)
    AC099050, AC113933, AK122683, BQ014539
    UniProtKB/TrEMBL
    B3KV54
    Conserved Domains (3) summary
    COG0553
    Location:49496
    HepA; Superfamily II DNA or RNA helicase, SNF2 family [Transcription, Replication, recombination and repair]
    cd00079
    Location:304451
    HELICc; Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may ...
    pfam15343
    Location:781867
    DEPP; Decidual protein induced by progesterone family
  4. NM_015106.4NP_055921.2  helicase ARIP4 isoform a

    See identical proteins and their annotated locations for NP_055921.2

    Status: VALIDATED

    Source sequence(s)
    AC092037, AC099050, AC113933
    Consensus CDS
    CCDS33765.2
    UniProtKB/Swiss-Prot
    Q9Y4B4
    UniProtKB/TrEMBL
    B3KV54
    Related
    ENSP00000386520.1, ENST00000409535.6
    Conserved Domains (4) summary
    cd00046
    Location:300492
    DEXDc; DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region.
    pfam00176
    Location:274628
    SNF2_N; SNF2 family N-terminal domain
    pfam00271
    Location:720854
    Helicase_C; Helicase conserved C-terminal domain
    pfam15343
    Location:11921278
    DEPP; Decidual protein induced by progesterone family

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000003.12 Reference GRCh38.p13 Primary Assembly

    Range
    51538719..51668660
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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