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Ablim2 actin-binding LIM protein 2 [ Mus musculus (house mouse) ]

Gene ID: 231148, updated on 30-Apr-2024

Summary

Official Symbol
Ablim2provided by MGI
Official Full Name
actin-binding LIM protein 2provided by MGI
Primary source
MGI:MGI:2385758
See related
Ensembl:ENSMUSG00000029095 AllianceGenome:MGI:2385758
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
C230091L11
Summary
Predicted to enable actin filament binding activity. Acts upstream of or within positive regulation of transcription by RNA polymerase II. Located in myofibril. Is expressed in several structures, including brain; diaphragm; early conceptus; oocyte; and skeletal muscle. Orthologous to human ABLIM2 (actin binding LIM protein family member 2). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Broad expression in cortex adult (RPKM 21.7), frontal lobe adult (RPKM 17.1) and 17 other tissues See more
Orthologs
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Genomic context

See Ablim2 in Genome Data Viewer
Location:
5 B3; 5 18.75 cM
Exon count:
26
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 5 NC_000071.7 (35915200..36042323)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 5 NC_000071.6 (35757855..35884979)

Chromosome 5 - NC_000071.7Genomic Context describing neighboring genes Neighboring gene STARR-seq mESC enhancer starr_12860 Neighboring gene HtrA serine peptidase 3 Neighboring gene STARR-positive B cell enhancer ABC_E8820 Neighboring gene SH3 domain and tetratricopeptide repeats 1 Neighboring gene predicted gene, 31888 Neighboring gene STARR-positive B cell enhancer ABC_E8050 Neighboring gene H2A histone family, pseudogene 1 Neighboring gene actin filament associated protein 1 Neighboring gene CapStarr-seq enhancer MGSCv37_chr5:36316611-36316857 Neighboring gene STARR-positive B cell enhancer mm9_chr5:36376513-36376814 Neighboring gene sortilin-related VPS10 domain containing receptor 2 Neighboring gene CapStarr-seq enhancer MGSCv37_chr5:36431991-36432296 Neighboring gene predicted gene, 52811

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Endonuclease-mediated (2) 

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables actin binding IEA
Inferred from Electronic Annotation
more info
 
enables actin filament binding IBA
Inferred from Biological aspect of Ancestor
more info
 
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
involved_in cytoskeleton organization IEA
Inferred from Electronic Annotation
more info
 
involved_in lamellipodium assembly IBA
Inferred from Biological aspect of Ancestor
more info
 
acts_upstream_of_or_within positive regulation of transcription by RNA polymerase II IMP
Inferred from Mutant Phenotype
more info
PubMed 
acts_upstream_of transcription by RNA polymerase II IMP
Inferred from Mutant Phenotype
more info
PubMed 
Component Evidence Code Pubs
is_active_in actin cytoskeleton IBA
Inferred from Biological aspect of Ancestor
more info
 
located_in actin cytoskeleton ISO
Inferred from Sequence Orthology
more info
PubMed 
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 
located_in myofibril IDA
Inferred from Direct Assay
more info
PubMed 

General protein information

Preferred Names
actin-binding LIM protein 2
Names
abLIM-2
actin-binding LIM protein family member 2

NCBI Reference Sequences (RefSeq)

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001177696.1NP_001171167.1  actin-binding LIM protein 2 isoform 1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) represents the longest transcript and encodes the longest isoform (1).
    Source sequence(s)
    AC141898
    Consensus CDS
    CCDS51473.1
    UniProtKB/TrEMBL
    E9Q4K0, Q19VH2
    Related
    ENSMUSP00000123525.2, ENSMUST00000129347.8
    Conserved Domains (6) summary
    cd09327
    Location:2475
    LIM1_abLIM; The first LIM domain of actin binding LIM (abLIM) proteins
    cd09328
    Location:80135
    LIM2_abLIM; The second LIM domain on actin binding LIM (abLIM) proteins
    cd09329
    Location:153204
    LIM3_abLIM; The third LIM domain of actin binding LIM (abLIM) proteins
    cd09330
    Location:212267
    LIM4_abLIM; The fourth LIM domain of actin binding LIM (abLIM) proteins
    pfam02209
    Location:630664
    VHP; Villin headpiece domain
    pfam16182
    Location:296628
    AbLIM_anchor; Putative adherens-junction anchoring region of AbLIM
  2. NM_001177697.1NP_001171168.1  actin-binding LIM protein 2 isoform 2

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) lacks three alternate exons and includes an alternate exon, compared to variant 1. The resulting isoform (2) lacks two internal segments and includes an additional internal segment, compared to isoform 1.
    Source sequence(s)
    AC141898, AK046243, AK046879
    Consensus CDS
    CCDS51475.1
    UniProtKB/TrEMBL
    Q3U409
    Related
    ENSMUSP00000109844.3, ENSMUST00000114206.9
    Conserved Domains (6) summary
    cd09327
    Location:2475
    LIM1_abLIM; The first LIM domain of actin binding LIM (abLIM) proteins
    cd09328
    Location:80135
    LIM2_abLIM; The second LIM domain on actin binding LIM (abLIM) proteins
    cd09329
    Location:153204
    LIM3_abLIM; The third LIM domain of actin binding LIM (abLIM) proteins
    cd09330
    Location:212267
    LIM4_abLIM; The fourth LIM domain of actin binding LIM (abLIM) proteins
    pfam02209
    Location:583617
    VHP; Villin headpiece domain
    pfam16182
    Location:277581
    AbLIM_anchor; Putative adherens-junction anchoring region of AbLIM
  3. NM_001177698.1NP_001171169.1  actin-binding LIM protein 2 isoform 4

    Status: VALIDATED

    Description
    Transcript Variant: This variant (4) lacks three alternate exons, compared to variant 1. The resulting isoform (4) lacks two internal segments, compared to isoform 1.
    Source sequence(s)
    AC141898
    Consensus CDS
    CCDS51474.1
    UniProtKB/TrEMBL
    E9Q0W6, Q3U409
    Related
    ENSMUSP00000098838.4, ENSMUST00000101280.10
    Conserved Domains (6) summary
    cd09327
    Location:2475
    LIM1_abLIM; The first LIM domain of actin binding LIM (abLIM) proteins
    cd09328
    Location:80135
    LIM2_abLIM; The second LIM domain on actin binding LIM (abLIM) proteins
    cd09329
    Location:153204
    LIM3_abLIM; The third LIM domain of actin binding LIM (abLIM) proteins
    cd09330
    Location:212267
    LIM4_abLIM; The fourth LIM domain of actin binding LIM (abLIM) proteins
    pfam02209
    Location:573607
    VHP; Villin headpiece domain
    pfam16182
    Location:296571
    AbLIM_anchor; Putative adherens-junction anchoring region of AbLIM
  4. NM_001177699.1NP_001171170.1  actin-binding LIM protein 2 isoform 5

    See identical proteins and their annotated locations for NP_001171170.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (5) lacks three alternate exons, compared to variant 1. The resulting isoform (5) lacks two internal segments, compared to isoform 1.
    Source sequence(s)
    AC141898, AY274116
    Consensus CDS
    CCDS51476.1
    UniProtKB/TrEMBL
    Q3U409
    Related
    ENSMUSP00000109842.2, ENSMUST00000114204.8
    Conserved Domains (6) summary
    cd09327
    Location:2475
    LIM1_abLIM; The first LIM domain of actin binding LIM (abLIM) proteins
    cd09328
    Location:80135
    LIM2_abLIM; The second LIM domain on actin binding LIM (abLIM) proteins
    cd09329
    Location:153204
    LIM3_abLIM; The third LIM domain of actin binding LIM (abLIM) proteins
    cd09330
    Location:212267
    LIM4_abLIM; The fourth LIM domain of actin binding LIM (abLIM) proteins
    pfam02209
    Location:572606
    VHP; Villin headpiece domain
    pfam16182
    Location:277570
    AbLIM_anchor; Putative adherens-junction anchoring region of AbLIM
  5. NM_001177700.1NP_001171171.1  actin-binding LIM protein 2 isoform 6

    See identical proteins and their annotated locations for NP_001171171.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (6) lacks four alternate exons, compared to variant 1. The resulting isoform (6) lacks three internal segments, compared to isoform 1.
    Source sequence(s)
    AC141898
    Consensus CDS
    CCDS51477.1
    UniProtKB/TrEMBL
    Q3U409
    Related
    ENSMUSP00000109843.2, ENSMUST00000114205.8
    Conserved Domains (6) summary
    cd09327
    Location:2475
    LIM1_abLIM; The first LIM domain of actin binding LIM (abLIM) proteins
    cd09328
    Location:80135
    LIM2_abLIM; The second LIM domain on actin binding LIM (abLIM) proteins
    cd09329
    Location:153204
    LIM3_abLIM; The third LIM domain of actin binding LIM (abLIM) proteins
    cd09330
    Location:212267
    LIM4_abLIM; The fourth LIM domain of actin binding LIM (abLIM) proteins
    pfam02209
    Location:539573
    VHP; Villin headpiece domain
    pfam16182
    Location:277537
    AbLIM_anchor; Putative adherens-junction anchoring region of AbLIM
  6. NM_177678.7NP_808346.3  actin-binding LIM protein 2 isoform 3

    See identical proteins and their annotated locations for NP_808346.3

    Status: VALIDATED

    Description
    Transcript Variant: This variant (3) lacks two alternate exons, compared to variant 1. The resulting isoform (3) lacks two internal segments, compared to isoform 1.
    Source sequence(s)
    AC141898, AK046243, AK046879
    Consensus CDS
    CCDS19235.1
    UniProtKB/Swiss-Prot
    B2RUF8, Q6H8P8, Q80WK6, Q8BL65, Q8BUT1, Q8BXI7
    UniProtKB/TrEMBL
    Q19VH2
    Related
    ENSMUSP00000050571.6, ENSMUST00000054598.12
    Conserved Domains (6) summary
    cd09327
    Location:2475
    LIM1_abLIM; The first LIM domain of actin binding LIM (abLIM) proteins
    cd09328
    Location:80135
    LIM2_abLIM; The second LIM domain on actin binding LIM (abLIM) proteins
    cd09329
    Location:153204
    LIM3_abLIM; The third LIM domain of actin binding LIM (abLIM) proteins
    cd09330
    Location:212267
    LIM4_abLIM; The fourth LIM domain of actin binding LIM (abLIM) proteins
    pfam02209
    Location:578612
    VHP; Villin headpiece domain
    pfam16182
    Location:277576
    AbLIM_anchor; Putative adherens-junction anchoring region of AbLIM

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000071.7 Reference GRCm39 C57BL/6J

    Range
    35915200..36042323
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006503906.2XP_006503969.1  actin-binding LIM protein 2 isoform X2

    UniProtKB/TrEMBL
    Q19VH2
    Conserved Domains (6) summary
    cd09327
    Location:2475
    LIM1_abLIM; The first LIM domain of actin binding LIM (abLIM) proteins
    cd09328
    Location:80135
    LIM2_abLIM; The second LIM domain on actin binding LIM (abLIM) proteins
    cd09329
    Location:153204
    LIM3_abLIM; The third LIM domain of actin binding LIM (abLIM) proteins
    cd09330
    Location:212267
    LIM4_abLIM; The fourth LIM domain of actin binding LIM (abLIM) proteins
    pfam02209
    Location:680714
    VHP; Villin headpiece domain
    pfam16182
    Location:295678
    AbLIM_anchor; Putative adherens-junction anchoring region of AbLIM
  2. XM_006503912.2XP_006503975.1  actin-binding LIM protein 2 isoform X13

    UniProtKB/TrEMBL
    Q19VH2
    Conserved Domains (6) summary
    cd09327
    Location:2475
    LIM1_abLIM; The first LIM domain of actin binding LIM (abLIM) proteins
    cd09328
    Location:80135
    LIM2_abLIM; The second LIM domain on actin binding LIM (abLIM) proteins
    cd09329
    Location:153204
    LIM3_abLIM; The third LIM domain of actin binding LIM (abLIM) proteins
    cd09330
    Location:212267
    LIM4_abLIM; The fourth LIM domain of actin binding LIM (abLIM) proteins
    pfam02209
    Location:640674
    VHP; Villin headpiece domain
    pfam16182
    Location:295638
    AbLIM_anchor; Putative adherens-junction anchoring region of AbLIM
  3. XM_030254381.2XP_030110241.1  actin-binding LIM protein 2 isoform X22

    UniProtKB/TrEMBL
    Q19VH2
    Conserved Domains (6) summary
    cd09327
    Location:2475
    LIM1_abLIM; The first LIM domain of actin binding LIM (abLIM) proteins
    cd09328
    Location:80135
    LIM2_abLIM; The second LIM domain on actin binding LIM (abLIM) proteins
    cd09329
    Location:153204
    LIM3_abLIM; The third LIM domain of actin binding LIM (abLIM) proteins
    cd09330
    Location:212267
    LIM4_abLIM; The fourth LIM domain of actin binding LIM (abLIM) proteins
    pfam02209
    Location:607641
    VHP; Villin headpiece domain
    pfam16182
    Location:295605
    AbLIM_anchor; Putative adherens-junction anchoring region of AbLIM
  4. XM_006503907.2XP_006503970.1  actin-binding LIM protein 2 isoform X4

    UniProtKB/TrEMBL
    Q19VH2
    Conserved Domains (6) summary
    cd09327
    Location:2475
    LIM1_abLIM; The first LIM domain of actin binding LIM (abLIM) proteins
    cd09328
    Location:80135
    LIM2_abLIM; The second LIM domain on actin binding LIM (abLIM) proteins
    cd09329
    Location:153204
    LIM3_abLIM; The third LIM domain of actin binding LIM (abLIM) proteins
    cd09330
    Location:212267
    LIM4_abLIM; The fourth LIM domain of actin binding LIM (abLIM) proteins
    pfam02209
    Location:669703
    VHP; Villin headpiece domain
    pfam16182
    Location:295667
    AbLIM_anchor; Putative adherens-junction anchoring region of AbLIM
  5. XM_006503908.2XP_006503971.1  actin-binding LIM protein 2 isoform X6

    UniProtKB/TrEMBL
    Q19VH2
    Conserved Domains (6) summary
    cd09327
    Location:2475
    LIM1_abLIM; The first LIM domain of actin binding LIM (abLIM) proteins
    cd09328
    Location:80135
    LIM2_abLIM; The second LIM domain on actin binding LIM (abLIM) proteins
    cd09329
    Location:153204
    LIM3_abLIM; The third LIM domain of actin binding LIM (abLIM) proteins
    cd09330
    Location:212267
    LIM4_abLIM; The fourth LIM domain of actin binding LIM (abLIM) proteins
    pfam02209
    Location:661695
    VHP; Villin headpiece domain
    pfam16182
    Location:276659
    AbLIM_anchor; Putative adherens-junction anchoring region of AbLIM
  6. XM_036165035.1XP_036020928.1  actin-binding LIM protein 2 isoform X18

    UniProtKB/TrEMBL
    Q19VH2
    Conserved Domains (6) summary
    cd09327
    Location:2475
    LIM1_abLIM; The first LIM domain of actin binding LIM (abLIM) proteins
    cd09328
    Location:80135
    LIM2_abLIM; The second LIM domain on actin binding LIM (abLIM) proteins
    cd09329
    Location:153204
    LIM3_abLIM; The third LIM domain of actin binding LIM (abLIM) proteins
    cd09330
    Location:212267
    LIM4_abLIM; The fourth LIM domain of actin binding LIM (abLIM) proteins
    pfam02209
    Location:621655
    VHP; Villin headpiece domain
    pfam16182
    Location:276620
    AbLIM_anchor; Putative adherens-junction anchoring region of AbLIM
  7. XM_036165042.1XP_036020935.1  actin-binding LIM protein 2 isoform X28

    UniProtKB/TrEMBL
    Q19VH2
    Conserved Domains (6) summary
    cd09327
    Location:2475
    LIM1_abLIM; The first LIM domain of actin binding LIM (abLIM) proteins
    cd09328
    Location:80135
    LIM2_abLIM; The second LIM domain on actin binding LIM (abLIM) proteins
    cd09329
    Location:153204
    LIM3_abLIM; The third LIM domain of actin binding LIM (abLIM) proteins
    cd09330
    Location:212267
    LIM4_abLIM; The fourth LIM domain of actin binding LIM (abLIM) proteins
    pfam02209
    Location:588622
    VHP; Villin headpiece domain
    pfam16182
    Location:276587
    AbLIM_anchor; Putative adherens-junction anchoring region of AbLIM
  8. XM_006503909.2XP_006503972.1  actin-binding LIM protein 2 isoform X9

    UniProtKB/TrEMBL
    Q19VH2
    Conserved Domains (6) summary
    cd09327
    Location:2475
    LIM1_abLIM; The first LIM domain of actin binding LIM (abLIM) proteins
    cd09328
    Location:80135
    LIM2_abLIM; The second LIM domain on actin binding LIM (abLIM) proteins
    cd09329
    Location:153204
    LIM3_abLIM; The third LIM domain of actin binding LIM (abLIM) proteins
    cd09330
    Location:212267
    LIM4_abLIM; The fourth LIM domain of actin binding LIM (abLIM) proteins
    pfam02209
    Location:650684
    VHP; Villin headpiece domain
    pfam16182
    Location:276648
    AbLIM_anchor; Putative adherens-junction anchoring region of AbLIM
  9. XM_030254383.2XP_030110243.1  actin-binding LIM protein 2 isoform X32

    UniProtKB/TrEMBL
    Q19VH2
    Conserved Domains (6) summary
    cd09327
    Location:2475
    LIM1_abLIM; The first LIM domain of actin binding LIM (abLIM) proteins
    cd09328
    Location:80135
    LIM2_abLIM; The second LIM domain on actin binding LIM (abLIM) proteins
    cd09329
    Location:153204
    LIM3_abLIM; The third LIM domain of actin binding LIM (abLIM) proteins
    cd09330
    Location:212267
    LIM4_abLIM; The fourth LIM domain of actin binding LIM (abLIM) proteins
    pfam02209
    Location:559593
    VHP; Villin headpiece domain
    pfam16182
    Location:276557
    AbLIM_anchor; Putative adherens-junction anchoring region of AbLIM
  10. XM_006503922.2XP_006503985.1  actin-binding LIM protein 2 isoform X33

    UniProtKB/TrEMBL
    Q19VH2
    Conserved Domains (6) summary
    smart00153
    Location:525560
    VHP; Villin headpiece domain
    cd09327
    Location:2475
    LIM1_abLIM; The first LIM domain of actin binding LIM (abLIM) proteins
    cd09328
    Location:80135
    LIM2_abLIM; The second LIM domain on actin binding LIM (abLIM) proteins
    cd09329
    Location:153204
    LIM3_abLIM; The third LIM domain of actin binding LIM (abLIM) proteins
    cd09330
    Location:212267
    LIM4_abLIM; The fourth LIM domain of actin binding LIM (abLIM) proteins
    pfam16182
    Location:276523
    AbLIM_anchor; Putative adherens-junction anchoring region of AbLIM
  11. XM_006503916.2XP_006503979.1  actin-binding LIM protein 2 isoform X21

    UniProtKB/TrEMBL
    Q19VH2
    Related
    ENSMUSP00000109848.3, ENSMUST00000114210.9
    Conserved Domains (6) summary
    cd09327
    Location:2475
    LIM1_abLIM; The first LIM domain of actin binding LIM (abLIM) proteins
    cd09328
    Location:80135
    LIM2_abLIM; The second LIM domain on actin binding LIM (abLIM) proteins
    cd09329
    Location:153204
    LIM3_abLIM; The third LIM domain of actin binding LIM (abLIM) proteins
    cd09330
    Location:212267
    LIM4_abLIM; The fourth LIM domain of actin binding LIM (abLIM) proteins
    pfam02209
    Location:610644
    VHP; Villin headpiece domain
    pfam16182
    Location:276608
    AbLIM_anchor; Putative adherens-junction anchoring region of AbLIM
  12. XM_030254382.2XP_030110242.1  actin-binding LIM protein 2 isoform X27

    UniProtKB/TrEMBL
    Q19VH2
    Conserved Domains (6) summary
    cd09327
    Location:2475
    LIM1_abLIM; The first LIM domain of actin binding LIM (abLIM) proteins
    cd09328
    Location:80135
    LIM2_abLIM; The second LIM domain on actin binding LIM (abLIM) proteins
    cd09329
    Location:153204
    LIM3_abLIM; The third LIM domain of actin binding LIM (abLIM) proteins
    cd09330
    Location:212267
    LIM4_abLIM; The fourth LIM domain of actin binding LIM (abLIM) proteins
    pfam02209
    Location:592626
    VHP; Villin headpiece domain
    pfam16182
    Location:276590
    AbLIM_anchor; Putative adherens-junction anchoring region of AbLIM
  13. XM_036165027.1XP_036020920.1  actin-binding LIM protein 2 isoform X8

    UniProtKB/TrEMBL
    Q19VH2
    Conserved Domains (6) summary
    cd09327
    Location:2980
    LIM1_abLIM; The first LIM domain of actin binding LIM (abLIM) proteins
    cd09328
    Location:85140
    LIM2_abLIM; The second LIM domain on actin binding LIM (abLIM) proteins
    cd09329
    Location:158209
    LIM3_abLIM; The third LIM domain of actin binding LIM (abLIM) proteins
    cd09330
    Location:217272
    LIM4_abLIM; The fourth LIM domain of actin binding LIM (abLIM) proteins
    pfam02209
    Location:652686
    VHP; Villin headpiece domain
    pfam16182
    Location:300651
    AbLIM_anchor; Putative adherens-junction anchoring region of AbLIM
  14. XM_036165033.1XP_036020926.1  actin-binding LIM protein 2 isoform X16

    UniProtKB/TrEMBL
    Q19VH2
    Conserved Domains (5) summary
    cd09327
    Location:2980
    LIM1_abLIM; The first LIM domain of actin binding LIM (abLIM) proteins
    cd09328
    Location:85140
    LIM2_abLIM; The second LIM domain on actin binding LIM (abLIM) proteins
    cd09329
    Location:158209
    LIM3_abLIM; The third LIM domain of actin binding LIM (abLIM) proteins
    cd09330
    Location:217272
    LIM4_abLIM; The fourth LIM domain of actin binding LIM (abLIM) proteins
    pfam16182
    Location:300657
    AbLIM_anchor; Putative adherens-junction anchoring region of AbLIM
  15. XM_036165039.1XP_036020932.1  actin-binding LIM protein 2 isoform X24

    UniProtKB/TrEMBL
    Q19VH2
    Conserved Domains (5) summary
    cd09327
    Location:2980
    LIM1_abLIM; The first LIM domain of actin binding LIM (abLIM) proteins
    cd09328
    Location:85140
    LIM2_abLIM; The second LIM domain on actin binding LIM (abLIM) proteins
    cd09329
    Location:158209
    LIM3_abLIM; The third LIM domain of actin binding LIM (abLIM) proteins
    cd09330
    Location:217272
    LIM4_abLIM; The fourth LIM domain of actin binding LIM (abLIM) proteins
    pfam16182
    Location:300632
    AbLIM_anchor; Putative adherens-junction anchoring region of AbLIM
  16. XM_036165043.1XP_036020936.1  actin-binding LIM protein 2 isoform X29

    UniProtKB/TrEMBL
    Q3U409
    Conserved Domains (5) summary
    cd09327
    Location:2980
    LIM1_abLIM; The first LIM domain of actin binding LIM (abLIM) proteins
    cd09328
    Location:85140
    LIM2_abLIM; The second LIM domain on actin binding LIM (abLIM) proteins
    cd09329
    Location:158209
    LIM3_abLIM; The third LIM domain of actin binding LIM (abLIM) proteins
    cd09330
    Location:217272
    LIM4_abLIM; The fourth LIM domain of actin binding LIM (abLIM) proteins
    pfam16182
    Location:300586
    AbLIM_anchor; Putative adherens-junction anchoring region of AbLIM
  17. XM_036165023.1XP_036020916.1  actin-binding LIM protein 2 isoform X1

    UniProtKB/TrEMBL
    Q19VH2
    Conserved Domains (6) summary
    cd09327
    Location:2980
    LIM1_abLIM; The first LIM domain of actin binding LIM (abLIM) proteins
    cd09328
    Location:85140
    LIM2_abLIM; The second LIM domain on actin binding LIM (abLIM) proteins
    cd09329
    Location:158209
    LIM3_abLIM; The third LIM domain of actin binding LIM (abLIM) proteins
    cd09330
    Location:217272
    LIM4_abLIM; The fourth LIM domain of actin binding LIM (abLIM) proteins
    pfam02209
    Location:685719
    VHP; Villin headpiece domain
    pfam16182
    Location:300684
    AbLIM_anchor; Putative adherens-junction anchoring region of AbLIM
  18. XM_036165030.1XP_036020923.1  actin-binding LIM protein 2 isoform X12

    UniProtKB/TrEMBL
    Q19VH2
    Conserved Domains (6) summary
    cd09327
    Location:2980
    LIM1_abLIM; The first LIM domain of actin binding LIM (abLIM) proteins
    cd09328
    Location:85140
    LIM2_abLIM; The second LIM domain on actin binding LIM (abLIM) proteins
    cd09329
    Location:158209
    LIM3_abLIM; The third LIM domain of actin binding LIM (abLIM) proteins
    cd09330
    Location:217272
    LIM4_abLIM; The fourth LIM domain of actin binding LIM (abLIM) proteins
    pfam02209
    Location:641675
    VHP; Villin headpiece domain
    pfam16182
    Location:300640
    AbLIM_anchor; Putative adherens-junction anchoring region of AbLIM
  19. XM_036165037.1XP_036020930.1  actin-binding LIM protein 2 isoform X20

    UniProtKB/TrEMBL
    Q19VH2
    Conserved Domains (6) summary
    cd09327
    Location:2980
    LIM1_abLIM; The first LIM domain of actin binding LIM (abLIM) proteins
    cd09328
    Location:85140
    LIM2_abLIM; The second LIM domain on actin binding LIM (abLIM) proteins
    cd09329
    Location:158209
    LIM3_abLIM; The third LIM domain of actin binding LIM (abLIM) proteins
    cd09330
    Location:217272
    LIM4_abLIM; The fourth LIM domain of actin binding LIM (abLIM) proteins
    pfam02209
    Location:612646
    VHP; Villin headpiece domain
    pfam16182
    Location:300611
    AbLIM_anchor; Putative adherens-junction anchoring region of AbLIM
  20. XM_036165034.1XP_036020927.1  actin-binding LIM protein 2 isoform X17

    UniProtKB/TrEMBL
    Q19VH2
    Conserved Domains (6) summary
    cd09327
    Location:2980
    LIM1_abLIM; The first LIM domain of actin binding LIM (abLIM) proteins
    cd09328
    Location:85140
    LIM2_abLIM; The second LIM domain on actin binding LIM (abLIM) proteins
    cd09329
    Location:158209
    LIM3_abLIM; The third LIM domain of actin binding LIM (abLIM) proteins
    cd09330
    Location:217272
    LIM4_abLIM; The fourth LIM domain of actin binding LIM (abLIM) proteins
    pfam02209
    Location:622656
    VHP; Villin headpiece domain
    pfam16182
    Location:281621
    AbLIM_anchor; Putative adherens-junction anchoring region of AbLIM
  21. XM_036165025.1XP_036020918.1  actin-binding LIM protein 2 isoform X5

    UniProtKB/TrEMBL
    Q19VH2
    Conserved Domains (6) summary
    cd09327
    Location:2980
    LIM1_abLIM; The first LIM domain of actin binding LIM (abLIM) proteins
    cd09328
    Location:85140
    LIM2_abLIM; The second LIM domain on actin binding LIM (abLIM) proteins
    cd09329
    Location:158209
    LIM3_abLIM; The third LIM domain of actin binding LIM (abLIM) proteins
    cd09330
    Location:217272
    LIM4_abLIM; The fourth LIM domain of actin binding LIM (abLIM) proteins
    pfam02209
    Location:666700
    VHP; Villin headpiece domain
    pfam16182
    Location:281665
    AbLIM_anchor; Putative adherens-junction anchoring region of AbLIM
  22. XM_036165028.1XP_036020921.1  actin-binding LIM protein 2 isoform X10

    UniProtKB/TrEMBL
    Q3U409
    Conserved Domains (6) summary
    cd09327
    Location:2980
    LIM1_abLIM; The first LIM domain of actin binding LIM (abLIM) proteins
    cd09328
    Location:85140
    LIM2_abLIM; The second LIM domain on actin binding LIM (abLIM) proteins
    cd09329
    Location:158209
    LIM3_abLIM; The third LIM domain of actin binding LIM (abLIM) proteins
    cd09330
    Location:217272
    LIM4_abLIM; The fourth LIM domain of actin binding LIM (abLIM) proteins
    pfam02209
    Location:646680
    VHP; Villin headpiece domain
    pfam16182
    Location:300645
    AbLIM_anchor; Putative adherens-junction anchoring region of AbLIM
  23. XM_036165032.1XP_036020925.1  actin-binding LIM protein 2 isoform X15

    UniProtKB/TrEMBL
    Q19VH2
    Conserved Domains (6) summary
    cd09327
    Location:2980
    LIM1_abLIM; The first LIM domain of actin binding LIM (abLIM) proteins
    cd09328
    Location:85140
    LIM2_abLIM; The second LIM domain on actin binding LIM (abLIM) proteins
    cd09329
    Location:158209
    LIM3_abLIM; The third LIM domain of actin binding LIM (abLIM) proteins
    cd09330
    Location:217272
    LIM4_abLIM; The fourth LIM domain of actin binding LIM (abLIM) proteins
    pfam02209
    Location:627661
    VHP; Villin headpiece domain
    pfam16182
    Location:300626
    AbLIM_anchor; Putative adherens-junction anchoring region of AbLIM
  24. XM_036165024.1XP_036020917.1  actin-binding LIM protein 2 isoform X3

    UniProtKB/TrEMBL
    Q19VH2
    Conserved Domains (6) summary
    cd09327
    Location:2980
    LIM1_abLIM; The first LIM domain of actin binding LIM (abLIM) proteins
    cd09328
    Location:85140
    LIM2_abLIM; The second LIM domain on actin binding LIM (abLIM) proteins
    cd09329
    Location:158209
    LIM3_abLIM; The third LIM domain of actin binding LIM (abLIM) proteins
    cd09330
    Location:217272
    LIM4_abLIM; The fourth LIM domain of actin binding LIM (abLIM) proteins
    pfam02209
    Location:674708
    VHP; Villin headpiece domain
    pfam16182
    Location:300673
    AbLIM_anchor; Putative adherens-junction anchoring region of AbLIM
  25. XM_036165041.1XP_036020934.1  actin-binding LIM protein 2 isoform X26

    UniProtKB/TrEMBL
    Q19VH2
    Conserved Domains (6) summary
    cd09327
    Location:2980
    LIM1_abLIM; The first LIM domain of actin binding LIM (abLIM) proteins
    cd09328
    Location:85140
    LIM2_abLIM; The second LIM domain on actin binding LIM (abLIM) proteins
    cd09329
    Location:158209
    LIM3_abLIM; The third LIM domain of actin binding LIM (abLIM) proteins
    cd09330
    Location:217272
    LIM4_abLIM; The fourth LIM domain of actin binding LIM (abLIM) proteins
    pfam02209
    Location:593627
    VHP; Villin headpiece domain
    pfam16182
    Location:281592
    AbLIM_anchor; Putative adherens-junction anchoring region of AbLIM
  26. XM_036165029.1XP_036020922.1  actin-binding LIM protein 2 isoform X11

    UniProtKB/TrEMBL
    Q19VH2
    Conserved Domains (6) summary
    cd09327
    Location:2980
    LIM1_abLIM; The first LIM domain of actin binding LIM (abLIM) proteins
    cd09328
    Location:85140
    LIM2_abLIM; The second LIM domain on actin binding LIM (abLIM) proteins
    cd09329
    Location:158209
    LIM3_abLIM; The third LIM domain of actin binding LIM (abLIM) proteins
    cd09330
    Location:217272
    LIM4_abLIM; The fourth LIM domain of actin binding LIM (abLIM) proteins
    pfam02209
    Location:645679
    VHP; Villin headpiece domain
    pfam16182
    Location:300644
    AbLIM_anchor; Putative adherens-junction anchoring region of AbLIM
  27. XM_036165040.1XP_036020933.1  actin-binding LIM protein 2 isoform X25

    UniProtKB/TrEMBL
    Q19VH2
    Conserved Domains (6) summary
    cd09327
    Location:2980
    LIM1_abLIM; The first LIM domain of actin binding LIM (abLIM) proteins
    cd09328
    Location:85140
    LIM2_abLIM; The second LIM domain on actin binding LIM (abLIM) proteins
    cd09329
    Location:158209
    LIM3_abLIM; The third LIM domain of actin binding LIM (abLIM) proteins
    cd09330
    Location:217272
    LIM4_abLIM; The fourth LIM domain of actin binding LIM (abLIM) proteins
    pfam02209
    Location:601635
    VHP; Villin headpiece domain
    pfam16182
    Location:300600
    AbLIM_anchor; Putative adherens-junction anchoring region of AbLIM
  28. XM_036165026.1XP_036020919.1  actin-binding LIM protein 2 isoform X7

    UniProtKB/TrEMBL
    Q19VH2
    Conserved Domains (6) summary
    cd09327
    Location:2980
    LIM1_abLIM; The first LIM domain of actin binding LIM (abLIM) proteins
    cd09328
    Location:85140
    LIM2_abLIM; The second LIM domain on actin binding LIM (abLIM) proteins
    cd09329
    Location:158209
    LIM3_abLIM; The third LIM domain of actin binding LIM (abLIM) proteins
    cd09330
    Location:217272
    LIM4_abLIM; The fourth LIM domain of actin binding LIM (abLIM) proteins
    pfam02209
    Location:655689
    VHP; Villin headpiece domain
    pfam16182
    Location:281654
    AbLIM_anchor; Putative adherens-junction anchoring region of AbLIM
  29. XM_036165045.1XP_036020938.1  actin-binding LIM protein 2 isoform X31

    UniProtKB/TrEMBL
    Q19VH2
    Conserved Domains (6) summary
    cd09327
    Location:2980
    LIM1_abLIM; The first LIM domain of actin binding LIM (abLIM) proteins
    cd09328
    Location:85140
    LIM2_abLIM; The second LIM domain on actin binding LIM (abLIM) proteins
    cd09329
    Location:158209
    LIM3_abLIM; The third LIM domain of actin binding LIM (abLIM) proteins
    cd09330
    Location:217272
    LIM4_abLIM; The fourth LIM domain of actin binding LIM (abLIM) proteins
    pfam02209
    Location:582616
    VHP; Villin headpiece domain
    pfam16182
    Location:281581
    AbLIM_anchor; Putative adherens-junction anchoring region of AbLIM
  30. XM_036165031.1XP_036020924.1  actin-binding LIM protein 2 isoform X14

    UniProtKB/TrEMBL
    Q19VH2
    Conserved Domains (6) summary
    cd09327
    Location:2980
    LIM1_abLIM; The first LIM domain of actin binding LIM (abLIM) proteins
    cd09328
    Location:85140
    LIM2_abLIM; The second LIM domain on actin binding LIM (abLIM) proteins
    cd09329
    Location:158209
    LIM3_abLIM; The third LIM domain of actin binding LIM (abLIM) proteins
    cd09330
    Location:217272
    LIM4_abLIM; The fourth LIM domain of actin binding LIM (abLIM) proteins
    pfam02209
    Location:634668
    VHP; Villin headpiece domain
    pfam16182
    Location:300633
    AbLIM_anchor; Putative adherens-junction anchoring region of AbLIM
  31. XM_036165038.1XP_036020931.1  actin-binding LIM protein 2 isoform X23

    UniProtKB/TrEMBL
    Q3U409
    Conserved Domains (6) summary
    cd09327
    Location:2980
    LIM1_abLIM; The first LIM domain of actin binding LIM (abLIM) proteins
    cd09328
    Location:85140
    LIM2_abLIM; The second LIM domain on actin binding LIM (abLIM) proteins
    cd09329
    Location:158209
    LIM3_abLIM; The third LIM domain of actin binding LIM (abLIM) proteins
    cd09330
    Location:217272
    LIM4_abLIM; The fourth LIM domain of actin binding LIM (abLIM) proteins
    pfam02209
    Location:606640
    VHP; Villin headpiece domain
    pfam16182
    Location:300605
    AbLIM_anchor; Putative adherens-junction anchoring region of AbLIM
  32. XM_036165044.1XP_036020937.1  actin-binding LIM protein 2 isoform X30

    UniProtKB/TrEMBL
    Q3U409
    Conserved Domains (6) summary
    cd09327
    Location:2980
    LIM1_abLIM; The first LIM domain of actin binding LIM (abLIM) proteins
    cd09328
    Location:85140
    LIM2_abLIM; The second LIM domain on actin binding LIM (abLIM) proteins
    cd09329
    Location:158209
    LIM3_abLIM; The third LIM domain of actin binding LIM (abLIM) proteins
    cd09330
    Location:217272
    LIM4_abLIM; The fourth LIM domain of actin binding LIM (abLIM) proteins
    pfam02209
    Location:587621
    VHP; Villin headpiece domain
    pfam16182
    Location:281586
    AbLIM_anchor; Putative adherens-junction anchoring region of AbLIM
  33. XM_036165036.1XP_036020929.1  actin-binding LIM protein 2 isoform X19

    UniProtKB/TrEMBL
    Q19VH2
    Conserved Domains (6) summary
    cd09327
    Location:2980
    LIM1_abLIM; The first LIM domain of actin binding LIM (abLIM) proteins
    cd09328
    Location:85140
    LIM2_abLIM; The second LIM domain on actin binding LIM (abLIM) proteins
    cd09329
    Location:158209
    LIM3_abLIM; The third LIM domain of actin binding LIM (abLIM) proteins
    cd09330
    Location:217272
    LIM4_abLIM; The fourth LIM domain of actin binding LIM (abLIM) proteins
    pfam02209
    Location:615649
    VHP; Villin headpiece domain
    pfam16182
    Location:281614
    AbLIM_anchor; Putative adherens-junction anchoring region of AbLIM
  34. XM_006503925.4XP_006503988.1  actin-binding LIM protein 2 isoform X34

    Conserved Domains (3) summary
    cl02475
    Location:124
    LIM; LIM is a small protein-protein interaction domain, containing two zinc fingers
    pfam02209
    Location:437471
    VHP; Villin headpiece domain
    pfam16182
    Location:52435
    AbLIM_anchor; Putative adherens-junction anchoring region of AbLIM
  35. XM_036165049.1XP_036020942.1  actin-binding LIM protein 2 isoform X40

    UniProtKB/TrEMBL
    D3Z0Y4
    Conserved Domains (3) summary
    pfam02209
    Location:364398
    VHP; Villin headpiece domain
    pfam16182
    Location:52363
    AbLIM_anchor; Putative adherens-junction anchoring region of AbLIM
    cl02475
    Location:124
    LIM; LIM is a small protein-protein interaction domain, containing two zinc fingers
  36. XM_006503926.4XP_006503989.1  actin-binding LIM protein 2 isoform X35

    Conserved Domains (3) summary
    smart00153
    Location:418453
    VHP; Villin headpiece domain
    cl02475
    Location:124
    LIM; LIM is a small protein-protein interaction domain, containing two zinc fingers
    pfam16182
    Location:33416
    AbLIM_anchor; Putative adherens-junction anchoring region of AbLIM
  37. XM_036165051.1XP_036020944.1  actin-binding LIM protein 2 isoform X42

    UniProtKB/TrEMBL
    D3Z0Y4
    Related
    ENSMUSP00000109841.2, ENSMUST00000114203.8
    Conserved Domains (3) summary
    smart00153
    Location:345380
    VHP; Villin headpiece domain
    pfam16182
    Location:33344
    AbLIM_anchor; Putative adherens-junction anchoring region of AbLIM
    cl02475
    Location:124
    LIM; LIM is a small protein-protein interaction domain, containing two zinc fingers
  38. XM_036165046.1XP_036020939.1  actin-binding LIM protein 2 isoform X36

    UniProtKB/TrEMBL
    D3Z0Y4
    Conserved Domains (3) summary
    pfam02209
    Location:397431
    VHP; Villin headpiece domain
    pfam16182
    Location:52396
    AbLIM_anchor; Putative adherens-junction anchoring region of AbLIM
    cl02475
    Location:124
    LIM; LIM is a small protein-protein interaction domain, containing two zinc fingers
  39. XM_036165048.1XP_036020941.1  actin-binding LIM protein 2 isoform X38

    UniProtKB/TrEMBL
    D3Z0Y4
    Conserved Domains (3) summary
    pfam02209
    Location:378412
    VHP; Villin headpiece domain
    pfam16182
    Location:33377
    AbLIM_anchor; Putative adherens-junction anchoring region of AbLIM
    cl02475
    Location:124
    LIM; LIM is a small protein-protein interaction domain, containing two zinc fingers
  40. XM_030254385.2XP_030110245.1  actin-binding LIM protein 2 isoform X43

    UniProtKB/TrEMBL
    D3Z0Y4
    Conserved Domains (3) summary
    smart00153
    Location:334369
    VHP; Villin headpiece domain
    cl02475
    Location:124
    LIM; LIM is a small protein-protein interaction domain, containing two zinc fingers
    pfam16182
    Location:33332
    AbLIM_anchor; Putative adherens-junction anchoring region of AbLIM
  41. XM_036165047.1XP_036020940.1  actin-binding LIM protein 2 isoform X37

    Conserved Domains (3) summary
    pfam02209
    Location:386420
    VHP; Villin headpiece domain
    pfam16182
    Location:52385
    AbLIM_anchor; Putative adherens-junction anchoring region of AbLIM
    cl02475
    Location:124
    LIM; LIM is a small protein-protein interaction domain, containing two zinc fingers
  42. XM_036165050.1XP_036020943.1  actin-binding LIM protein 2 isoform X41

    UniProtKB/TrEMBL
    D3Z0Y4
    Conserved Domains (3) summary
    pfam02209
    Location:349383
    VHP; Villin headpiece domain
    pfam16182
    Location:33348
    AbLIM_anchor; Putative adherens-junction anchoring region of AbLIM
    cl02475
    Location:124
    LIM; LIM is a small protein-protein interaction domain, containing two zinc fingers
  43. XM_030254384.2XP_030110244.1  actin-binding LIM protein 2 isoform X39

    UniProtKB/TrEMBL
    D3Z0Y4
    Conserved Domains (3) summary
    smart00153
    Location:367402
    VHP; Villin headpiece domain
    cl02475
    Location:124
    LIM; LIM is a small protein-protein interaction domain, containing two zinc fingers
    pfam16182
    Location:33365
    AbLIM_anchor; Putative adherens-junction anchoring region of AbLIM

RNA

  1. XR_004942495.1 RNA Sequence