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NFASC neurofascin [ Homo sapiens (human) ]

Gene ID: 23114, updated on 3-Jan-2019

Summary

Official Symbol
NFASCprovided by HGNC
Official Full Name
neurofascinprovided by HGNC
Primary source
HGNC:HGNC:29866
See related
Ensembl:ENSG00000163531 MIM:609145
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
NF; NRCAML
Summary
This gene encodes an L1 family immunoglobulin cell adhesion molecule with multiple IGcam and fibronectin domains. The protein functions in neurite outgrowth, neurite fasciculation, and organization of the axon initial segment (AIS) and nodes of Ranvier on axons during early development. Both the AIS and nodes of Ranvier contain high densities of voltage-gated Na+ (Nav) channels which are clustered by interactions with cytoskeletal and scaffolding proteins including this protein, gliomedin, ankyrin 3 (ankyrin-G), and betaIV spectrin. This protein links the AIS extracellular matrix to the intracellular cytoskeleton. This gene undergoes extensive alternative splicing, and the full-length nature of some variants has not been determined.[provided by RefSeq, May 2009]
Expression
Broad expression in brain (RPKM 17.7), kidney (RPKM 6.6) and 19 other tissues See more
Orthologs

Genomic context

See NFASC in Genome Data Viewer
Location:
1q32.1
Exon count:
36
Annotation release Status Assembly Chr Location
109 current GRCh38.p12 (GCF_000001405.38) 1 NC_000001.11 (204828652..205022822)
105 previous assembly GRCh37.p13 (GCF_000001405.25) 1 NC_000001.10 (204797782..204991950)

Chromosome 1 - NC_000001.11Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC105371693 Neighboring gene uncharacterized LOC105371695 Neighboring gene uncharacterized LOC105371694 Neighboring gene ribosomal protein L13a pseudogene 11 Neighboring gene contactin 2 Neighboring gene transmembrane protein 81

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

Phenotypes

NHGRI GWAS Catalog

Description
Clozapine-induced agranulocytosis is associated with rare HLA-DQB1 and HLA-B alleles.
NHGRI GWA Catalog
Genome-wide association study combining pathway analysis for typical sporadic amyotrophic lateral sclerosis in Chinese Han populations.
NHGRI GWA Catalog
GWAS of dental caries patterns in the permanent dentition.
NHGRI GWA Catalog
NCK2 is significantly associated with opiates addiction in African-origin men.
NHGRI GWA Catalog

Pathways from BioSystems

  • Axon guidance, organism-specific biosystem (from REACTOME)
    Axon guidance, organism-specific biosystemAxon guidance / axon pathfinding is the process by which neurons send out axons to reach the correct targets. Growing axons have a highly motile structure at the growing tip called the growth cone, w...
  • Cell adhesion molecules (CAMs), organism-specific biosystem (from KEGG)
    Cell adhesion molecules (CAMs), organism-specific biosystemCell adhesion molecules are (glyco)proteins expressed on the cell surface and play a critical role in a wide array of biologic processes that include hemostasis, the immune response, inflammation, em...
  • Cell adhesion molecules (CAMs), conserved biosystem (from KEGG)
    Cell adhesion molecules (CAMs), conserved biosystemCell adhesion molecules are (glyco)proteins expressed on the cell surface and play a critical role in a wide array of biologic processes that include hemostasis, the immune response, inflammation, em...
  • Developmental Biology, organism-specific biosystem (from REACTOME)
    Developmental Biology, organism-specific biosystemAs a first step towards capturing the array of processes by which a fertilized egg gives rise to the diverse tissues of the body, examples of three kinds of processes have been annotated. These are a...
  • Immune System, organism-specific biosystem (from REACTOME)
    Immune System, organism-specific biosystemHumans are exposed to millions of potential pathogens daily, through contact, ingestion, and inhalation. Our ability to avoid infection depends on the adaptive immune system and during the first crit...
  • Innate Immune System, organism-specific biosystem (from REACTOME)
    Innate Immune System, organism-specific biosystemInnate immunity encompases the nonspecific part of immunity tha are part of an individual's natural biologic makeup
  • Interaction between L1 and Ankyrins, organism-specific biosystem (from REACTOME)
    Interaction between L1 and Ankyrins, organism-specific biosystemAnkyrins are a family of adaptor proteins that couple membrane proteins such as voltage gated Na+ channels and the Na+/K+ anion exchanger to the spectrin actin cytoskeleton. Ankyrins are encoded by t...
  • L1CAM interactions, organism-specific biosystem (from REACTOME)
    L1CAM interactions, organism-specific biosystemThe L1 family of cell adhesion molecules (L1CAMs) are a subfamily of the immunoglobulin superfamily of transmembrane receptors, comprised of four structurally related proteins: L1, Close Homolog of L...
  • Neurofascin interactions, organism-specific biosystem (from REACTOME)
    Neurofascin interactions, organism-specific biosystemNeurofascin is an L1 family immunoglobulin cell adhesion molecule involved in axon subcellular targeting and synapse formation during neural development. There are a range of different isoforms ident...
  • Neutrophil degranulation, organism-specific biosystem (from REACTOME)
    Neutrophil degranulation, organism-specific biosystemNeutrophils are the most abundant leukocytes (white blood cells), indispensable in defending the body against invading microorganisms. In response to infection, neutrophils leave the circulation and ...

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Clone Names

  • FLJ46866, KIAA0756, DKFZp686P2250

Gene Ontology Provided by GOA

Function Evidence Code Pubs
protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
protein binding involved in heterotypic cell-cell adhesion IEA
Inferred from Electronic Annotation
more info
 
protein domain specific binding IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
axon guidance IEA
Inferred from Electronic Annotation
more info
 
clustering of voltage-gated sodium channels IEA
Inferred from Electronic Annotation
more info
 
heterotypic cell-cell adhesion IEA
Inferred from Electronic Annotation
more info
 
myelination ISS
Inferred from Sequence or Structural Similarity
more info
 
neutrophil degranulation TAS
Traceable Author Statement
more info
 
paranodal junction assembly IEA
Inferred from Electronic Annotation
more info
 
peripheral nervous system development ISS
Inferred from Sequence or Structural Similarity
more info
 
protein localization to juxtaparanode region of axon IEA
Inferred from Electronic Annotation
more info
 
protein localization to paranode region of axon IEA
Inferred from Electronic Annotation
more info
 
protein localization to plasma membrane IEA
Inferred from Electronic Annotation
more info
 
synapse organization IEA
Inferred from Electronic Annotation
more info
 
transmission of nerve impulse IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
Schwann cell microvillus IEA
Inferred from Electronic Annotation
more info
 
axon initial segment ISS
Inferred from Sequence or Structural Similarity
more info
 
dendrite IEA
Inferred from Electronic Annotation
more info
 
ficolin-1-rich granule membrane TAS
Traceable Author Statement
more info
 
focal adhesion HDA PubMed 
integral component of plasma membrane IEA
Inferred from Electronic Annotation
more info
 
node of Ranvier ISS
Inferred from Sequence or Structural Similarity
more info
 
node of Ranvier TAS
Traceable Author Statement
more info
PubMed 
paranodal junction IEA
Inferred from Electronic Annotation
more info
 
paranode region of axon IEA
Inferred from Electronic Annotation
more info
 
plasma membrane TAS
Traceable Author Statement
more info
 

General protein information

Preferred Names
neurofascin
Names
neurofascin homolog
neurofascin isoform 140

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

Genomic

  1. NG_029938.1 RefSeqGene

    Range
    5001..199169
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001005388.2NP_001005388.2  neurofascin isoform 1 precursor

    See identical proteins and their annotated locations for NP_001005388.2

    Status: REVIEWED

    Description
    Transcript Variant: This variant (1) represents the longest transcript and encodes the longest isoform (1). This isoform lacks the third fibronectin type 3 (FNIII) repeat and includes the mucin-like domain. Isoform 1 is also known as NF186, as described by Davis et al. (PMID: 8947556).
    Source sequence(s)
    AB018299, AL391822, BC035389, BC040674, BC117674
    Consensus CDS
    CCDS53460.1
    UniProtKB/Swiss-Prot
    O94856
    Related
    ENSP00000344786.6, ENST00000339876.10
    Conserved Domains (8) summary
    cd05875
    Location:59135
    Ig_hNeurofascin_like; Immunoglobulin (Ig)-like domain of human neurofascin (NF)
    cd00063
    Location:628718
    FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
    pfam00041
    Location:10141086
    fn3; Fibronectin type III domain
    pfam13882
    Location:11321216
    Bravo_FIGEY; Bravo-like intracellular region
    cd00096
    Location:449515
    Ig; Immunoglobulin domain
    cd05731
    Location:264334
    Ig3_L1-CAM_like; Third immunoglobulin (Ig)-like domain of the L1 cell adhesion molecule (CAM)
    cl11960
    Location:140232
    Ig; Immunoglobulin domain
    cl28434
    Location:528609
    I-set; Immunoglobulin I-set domain
  2. NM_001005389.1NP_001005389.2  neurofascin isoform 5 precursor

    See identical proteins and their annotated locations for NP_001005389.2

    Status: REVIEWED

    Description
    Transcript Variant: This variant (5) uses an alternate 3' coding region and 3' UTR, compared to variant 1. The resulting isoform (5) has a substantially shorter and distinct C-terminus that lacks the fibronectin domains, compared to isoform 1.
    Source sequence(s)
    AA514945, AK090639, BC040674
    Consensus CDS
    CCDS53461.1
    UniProtKB/Swiss-Prot
    O94856
    Related
    ENSP00000384875.1, ENST00000403080.5
    Conserved Domains (6) summary
    cd05731
    Location:264334
    Ig3_L1-CAM_like; Third immunoglobulin (Ig)-like domain of the L1 cell adhesion molecule (CAM)
    cd05875
    Location:59135
    Ig6_hNeurofascin_like; Sixth immunoglobulin (Ig)-like domain of human neurofascin (NF)
    smart00408
    Location:449508
    IGc2; Immunoglobulin C-2 Type
    smart00410
    Location:254333
    IG_like; Immunoglobulin like
    pfam07679
    Location:528609
    I-set; Immunoglobulin I-set domain
    cl11960
    Location:140232
    Ig; Immunoglobulin domain
  3. NM_001160331.1NP_001153803.1  neurofascin isoform 2 precursor

    Status: REVIEWED

    Description
    Transcript Variant: This variant (2) has multiple differences in the coding region but maintains the reading frame, compared to variant 1. The promoter and 5' UTR for this variant have not been determined. The resulting isoform (2) includes the third fibronectin type 3 (FNIII) repeat, lacks the mucin-like domain, and has several differences near the N-terminus, compared to isoform 1. Isoform 2 is also known as NF155, as described by Davis et al. (PMID: 8947556).
    Source sequence(s)
    AL391822, BC035389
    UniProtKB/Swiss-Prot
    O94856
    Related
    ENSP00000415031.1, ENST00000430393.5
    Conserved Domains (8) summary
    cd05731
    Location:275345
    Ig3_L1-CAM_like; Third immunoglobulin (Ig)-like domain of the L1 cell adhesion molecule (CAM)
    cd05875
    Location:53129
    Ig6_hNeurofascin_like; Sixth immunoglobulin (Ig)-like domain of human neurofascin (NF)
    smart00408
    Location:460519
    IGc2; Immunoglobulin C-2 Type
    smart00410
    Location:265344
    IG_like; Immunoglobulin like
    cd00063
    Location:639729
    FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
    pfam07679
    Location:539620
    I-set; Immunoglobulin I-set domain
    pfam13882
    Location:10811165
    Bravo_FIGEY; Bravo-like intracellular region
    cl11960
    Location:134226
    Ig; Immunoglobulin domain
  4. NM_001160332.1NP_001153804.1  neurofascin isoform 3 precursor

    Status: REVIEWED

    Description
    Transcript Variant: This variant (3) has multiple differences in the coding region but maintains the reading frame, compared to variant 1. The resulting isoform (3) includes the third fibronectin type 3 (FNIII) repeat, lacks the mucin-like domain, and has several differences in the N-terminal and central regions, compared to isoform 1.
    Source sequence(s)
    AC096675, AL391822, BC035389
    Consensus CDS
    CCDS53462.1
    UniProtKB/Swiss-Prot
    O94856
    Related
    ENSP00000438614.1, ENST00000539706.5
    Conserved Domains (8) summary
    cd05731
    Location:275345
    Ig3_L1-CAM_like; Third immunoglobulin (Ig)-like domain of the L1 cell adhesion molecule (CAM)
    cd05875
    Location:53129
    Ig6_hNeurofascin_like; Sixth immunoglobulin (Ig)-like domain of human neurofascin (NF)
    smart00408
    Location:460519
    IGc2; Immunoglobulin C-2 Type
    smart00410
    Location:265344
    IG_like; Immunoglobulin like
    cd00063
    Location:624714
    FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
    pfam07679
    Location:539620
    I-set; Immunoglobulin I-set domain
    pfam13882
    Location:10661150
    Bravo_FIGEY; Bravo-like intracellular region
    cl11960
    Location:134226
    Ig; Immunoglobulin domain
  5. NM_001160333.1NP_001153805.1  neurofascin isoform 6 precursor

    Status: REVIEWED

    Description
    Transcript Variant: This variant (6) lacks the second coding exon and uses an alternate 3' coding region and 3' UTR, compared to variant 1. The resulting isoform (5) lacks an internal domain and has a substantially shorter and distinct C-terminus that lacks the fibronectin domains, compared to isoform 1.
    Source sequence(s)
    AA514945, AK090639, AK299262, BC040674
    UniProtKB/Swiss-Prot
    O94856
    UniProtKB/TrEMBL
    B4DRH7
    Conserved Domains (6) summary
    cd05731
    Location:258328
    Ig3_L1-CAM_like; Third immunoglobulin (Ig)-like domain of the L1 cell adhesion molecule (CAM)
    cd05875
    Location:53129
    Ig6_hNeurofascin_like; Sixth immunoglobulin (Ig)-like domain of human neurofascin (NF)
    smart00408
    Location:443502
    IGc2; Immunoglobulin C-2 Type
    smart00410
    Location:248327
    IG_like; Immunoglobulin like
    pfam07679
    Location:522603
    I-set; Immunoglobulin I-set domain
    cl11960
    Location:134226
    Ig; Immunoglobulin domain
  6. NM_001365986.1NP_001352915.1  neurofascin isoform 7 precursor

    Status: REVIEWED

    Source sequence(s)
    AC096675, AL391822
    Conserved Domains (7) summary
    cd05875
    Location:53129
    Ig_hNeurofascin_like; Immunoglobulin (Ig)-like domain of human neurofascin (NF)
    cd00063
    Location:624714
    FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
    pfam07679
    Location:539620
    I-set; Immunoglobulin I-set domain
    pfam13882
    Location:9541038
    Bravo_FIGEY; Bravo-like intracellular region
    cd00096
    Location:460526
    Ig; Immunoglobulin domain
    cd05731
    Location:275345
    Ig3_L1-CAM_like; Third immunoglobulin (Ig)-like domain of the L1 cell adhesion molecule (CAM)
    cl11960
    Location:134226
    Ig; Immunoglobulin domain
  7. NM_015090.3NP_055905.2  neurofascin isoform 4 precursor

    See identical proteins and their annotated locations for NP_055905.2

    Status: REVIEWED

    Description
    Transcript Variant: This variant (4) has multiple differences in the coding region but maintains the reading frame, compared to variant 1. The resulting isoform (4) includes the third fibronectin type 3 (FNIII) repeat, lacks the mucin-like domain, and has several differences in the N-terminal and central regions, compared to isoform 1.
    Source sequence(s)
    AB018299, AL391822, BC035389, BC040674
    Consensus CDS
    CCDS30982.1
    UniProtKB/Swiss-Prot
    O94856
    Related
    ENSP00000353154.4, ENST00000360049.8
    Conserved Domains (8) summary
    cd05731
    Location:275345
    Ig3_L1-CAM_like; Third immunoglobulin (Ig)-like domain of the L1 cell adhesion molecule (CAM)
    cd05875
    Location:53129
    Ig6_hNeurofascin_like; Sixth immunoglobulin (Ig)-like domain of human neurofascin (NF)
    smart00408
    Location:460519
    IGc2; Immunoglobulin C-2 Type
    smart00410
    Location:265344
    IG_like; Immunoglobulin like
    cd00063
    Location:624714
    FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
    pfam07679
    Location:539620
    I-set; Immunoglobulin I-set domain
    pfam13882
    Location:10611145
    Bravo_FIGEY; Bravo-like intracellular region
    cl11960
    Location:134226
    Ig; Immunoglobulin domain

RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 109

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p12 Primary Assembly

Genomic

  1. NC_000001.11 Reference GRCh38.p12 Primary Assembly

    Range
    204828652..205022822
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_011509318.2XP_011507620.1  neurofascin isoform X11

    Conserved Domains (9) summary
    cd05731
    Location:377447
    Ig3_L1-CAM_like; Third immunoglobulin (Ig)-like domain of the L1 cell adhesion molecule (CAM)
    cd05875
    Location:155231
    Ig6_hNeurofascin_like; Sixth immunoglobulin (Ig)-like domain of human neurofascin (NF)
    smart00408
    Location:562621
    IGc2; Immunoglobulin C-2 Type
    smart00410
    Location:367446
    IG_like; Immunoglobulin like
    cd00063
    Location:741831
    FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
    pfam07679
    Location:641722
    I-set; Immunoglobulin I-set domain
    pfam00041
    Location:12351306
    fn3; Fibronectin type III domain
    pfam13882
    Location:13521436
    Bravo_FIGEY; Bravo-like intracellular region
    cl11960
    Location:236328
    Ig; Immunoglobulin domain
  2. XM_017000738.1XP_016856227.1  neurofascin isoform X25

  3. XM_017000739.1XP_016856228.1  neurofascin isoform X26

  4. XM_017000740.1XP_016856229.1  neurofascin isoform X30

  5. XM_011509320.2XP_011507622.1  neurofascin isoform X13

    Conserved Domains (9) summary
    cd05731
    Location:360430
    Ig3_L1-CAM_like; Third immunoglobulin (Ig)-like domain of the L1 cell adhesion molecule (CAM)
    cd05875
    Location:155231
    Ig6_hNeurofascin_like; Sixth immunoglobulin (Ig)-like domain of human neurofascin (NF)
    smart00408
    Location:545604
    IGc2; Immunoglobulin C-2 Type
    smart00410
    Location:350429
    IG_like; Immunoglobulin like
    cd00063
    Location:724814
    FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
    pfam07679
    Location:624705
    I-set; Immunoglobulin I-set domain
    pfam00041
    Location:12181289
    fn3; Fibronectin type III domain
    pfam13882
    Location:13351419
    Bravo_FIGEY; Bravo-like intracellular region
    cl11960
    Location:236328
    Ig; Immunoglobulin domain
  6. XM_017000743.1XP_016856232.1  neurofascin isoform X35

    UniProtKB/TrEMBL
    B4DRH7
    Conserved Domains (6) summary
    cd05731
    Location:360430
    Ig3_L1-CAM_like; Third immunoglobulin (Ig)-like domain of the L1 cell adhesion molecule (CAM)
    cd05875
    Location:155231
    Ig6_hNeurofascin_like; Sixth immunoglobulin (Ig)-like domain of human neurofascin (NF)
    smart00408
    Location:545604
    IGc2; Immunoglobulin C-2 Type
    smart00410
    Location:350429
    IG_like; Immunoglobulin like
    pfam07679
    Location:624705
    I-set; Immunoglobulin I-set domain
    cl11960
    Location:236328
    Ig; Immunoglobulin domain
  7. XM_024454300.1XP_024310068.1  neurofascin isoform X27

    Conserved Domains (8) summary
    cd05875
    Location:59135
    Ig_hNeurofascin_like; Immunoglobulin (Ig)-like domain of human neurofascin (NF)
    cd00063
    Location:628718
    FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
    pfam00041
    Location:10141086
    fn3; Fibronectin type III domain
    pfam13882
    Location:11321216
    Bravo_FIGEY; Bravo-like intracellular region
    cd00096
    Location:449515
    Ig; Immunoglobulin domain
    cd05731
    Location:264334
    Ig3_L1-CAM_like; Third immunoglobulin (Ig)-like domain of the L1 cell adhesion molecule (CAM)
    cl11960
    Location:140232
    Ig; Immunoglobulin domain
    cl28434
    Location:528609
    I-set; Immunoglobulin I-set domain
  8. XM_011509316.1XP_011507618.1  neurofascin isoform X10

    Conserved Domains (9) summary
    cd05731
    Location:281351
    Ig3_L1-CAM_like; Third immunoglobulin (Ig)-like domain of the L1 cell adhesion molecule (CAM)
    cd05875
    Location:59135
    Ig6_hNeurofascin_like; Sixth immunoglobulin (Ig)-like domain of human neurofascin (NF)
    smart00408
    Location:466525
    IGc2; Immunoglobulin C-2 Type
    smart00410
    Location:271350
    IG_like; Immunoglobulin like
    cd00063
    Location:645735
    FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
    pfam07679
    Location:545626
    I-set; Immunoglobulin I-set domain
    pfam00041
    Location:11391210
    fn3; Fibronectin type III domain
    pfam13882
    Location:12561340
    Bravo_FIGEY; Bravo-like intracellular region
    cl11960
    Location:140232
    Ig; Immunoglobulin domain
  9. XM_011509319.1XP_011507621.1  neurofascin isoform X12

    See identical proteins and their annotated locations for XP_011507621.1

    UniProtKB/Swiss-Prot
    O94856
    Conserved Domains (9) summary
    cd05731
    Location:264334
    Ig3_L1-CAM_like; Third immunoglobulin (Ig)-like domain of the L1 cell adhesion molecule (CAM)
    cd05875
    Location:59135
    Ig6_hNeurofascin_like; Sixth immunoglobulin (Ig)-like domain of human neurofascin (NF)
    smart00408
    Location:449508
    IGc2; Immunoglobulin C-2 Type
    smart00410
    Location:254333
    IG_like; Immunoglobulin like
    cd00063
    Location:628718
    FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
    pfam07679
    Location:528609
    I-set; Immunoglobulin I-set domain
    pfam00041
    Location:11221193
    fn3; Fibronectin type III domain
    pfam13882
    Location:12391323
    Bravo_FIGEY; Bravo-like intracellular region
    cl11960
    Location:140232
    Ig; Immunoglobulin domain
  10. XM_024454301.1XP_024310069.1  neurofascin isoform X31

    Conserved Domains (6) summary
    cd05875
    Location:59135
    Ig_hNeurofascin_like; Immunoglobulin (Ig)-like domain of human neurofascin (NF)
    cd00063
    Location:628718
    FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
    pfam07679
    Location:528609
    I-set; Immunoglobulin I-set domain
    cd00096
    Location:449515
    Ig; Immunoglobulin domain
    cd05731
    Location:264334
    Ig3_L1-CAM_like; Third immunoglobulin (Ig)-like domain of the L1 cell adhesion molecule (CAM)
    cl11960
    Location:140232
    Ig; Immunoglobulin domain
  11. XM_024454302.1XP_024310070.1  neurofascin isoform X31

    Conserved Domains (6) summary
    cd05875
    Location:59135
    Ig_hNeurofascin_like; Immunoglobulin (Ig)-like domain of human neurofascin (NF)
    cd00063
    Location:628718
    FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
    pfam07679
    Location:528609
    I-set; Immunoglobulin I-set domain
    cd00096
    Location:449515
    Ig; Immunoglobulin domain
    cd05731
    Location:264334
    Ig3_L1-CAM_like; Third immunoglobulin (Ig)-like domain of the L1 cell adhesion molecule (CAM)
    cl11960
    Location:140232
    Ig; Immunoglobulin domain
  12. XM_024454283.1XP_024310051.1  neurofascin isoform X1

    Conserved Domains (8) summary
    cd05875
    Location:208284
    Ig_hNeurofascin_like; Immunoglobulin (Ig)-like domain of human neurofascin (NF)
    cd00063
    Location:794884
    FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
    pfam07679
    Location:694775
    I-set; Immunoglobulin I-set domain
    pfam00041
    Location:12871359
    fn3; Fibronectin type III domain
    pfam13882
    Location:14051489
    Bravo_FIGEY; Bravo-like intracellular region
    cd00096
    Location:615681
    Ig; Immunoglobulin domain
    cd05731
    Location:430500
    Ig3_L1-CAM_like; Third immunoglobulin (Ig)-like domain of the L1 cell adhesion molecule (CAM)
    cl11960
    Location:289381
    Ig; Immunoglobulin domain
  13. XM_011509311.2XP_011507613.2  neurofascin isoform X2

    Conserved Domains (8) summary
    cd05875
    Location:208284
    Ig_hNeurofascin_like; Immunoglobulin (Ig)-like domain of human neurofascin (NF)
    cd00063
    Location:794884
    FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
    pfam07679
    Location:694775
    I-set; Immunoglobulin I-set domain
    pfam00041
    Location:12821354
    fn3; Fibronectin type III domain
    pfam13882
    Location:14001484
    Bravo_FIGEY; Bravo-like intracellular region
    cd00096
    Location:615681
    Ig; Immunoglobulin domain
    cd05731
    Location:430500
    Ig3_L1-CAM_like; Third immunoglobulin (Ig)-like domain of the L1 cell adhesion molecule (CAM)
    cl11960
    Location:289381
    Ig; Immunoglobulin domain
  14. XM_024454285.1XP_024310053.1  neurofascin isoform X4

    Conserved Domains (8) summary
    cd05875
    Location:208284
    Ig_hNeurofascin_like; Immunoglobulin (Ig)-like domain of human neurofascin (NF)
    cd00063
    Location:779869
    FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
    pfam07679
    Location:694775
    I-set; Immunoglobulin I-set domain
    pfam00041
    Location:12721344
    fn3; Fibronectin type III domain
    pfam13882
    Location:13901474
    Bravo_FIGEY; Bravo-like intracellular region
    cd00096
    Location:615681
    Ig; Immunoglobulin domain
    cd05731
    Location:430500
    Ig3_L1-CAM_like; Third immunoglobulin (Ig)-like domain of the L1 cell adhesion molecule (CAM)
    cl11960
    Location:289381
    Ig; Immunoglobulin domain
  15. XM_024454292.1XP_024310060.1  neurofascin isoform X8

    Conserved Domains (8) summary
    cd05875
    Location:208284
    Ig_hNeurofascin_like; Immunoglobulin (Ig)-like domain of human neurofascin (NF)
    cd00063
    Location:762852
    FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
    pfam07679
    Location:677758
    I-set; Immunoglobulin I-set domain
    pfam00041
    Location:12551327
    fn3; Fibronectin type III domain
    pfam13882
    Location:13731457
    Bravo_FIGEY; Bravo-like intracellular region
    cd00096
    Location:598664
    Ig; Immunoglobulin domain
    cd05731
    Location:413483
    Ig3_L1-CAM_like; Third immunoglobulin (Ig)-like domain of the L1 cell adhesion molecule (CAM)
    cl11960
    Location:289381
    Ig; Immunoglobulin domain
  16. XM_011509322.2XP_011507624.2  neurofascin isoform X15

    Conserved Domains (7) summary
    cd05875
    Location:208284
    Ig_hNeurofascin_like; Immunoglobulin (Ig)-like domain of human neurofascin (NF)
    cd00063
    Location:794884
    FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
    pfam07679
    Location:694775
    I-set; Immunoglobulin I-set domain
    pfam13882
    Location:13151399
    Bravo_FIGEY; Bravo-like intracellular region
    cd00096
    Location:615681
    Ig; Immunoglobulin domain
    cd05731
    Location:430500
    Ig3_L1-CAM_like; Third immunoglobulin (Ig)-like domain of the L1 cell adhesion molecule (CAM)
    cl11960
    Location:289381
    Ig; Immunoglobulin domain
  17. XM_011509321.2XP_011507623.2  neurofascin isoform X14

    Conserved Domains (8) summary
    cd05875
    Location:208284
    Ig_hNeurofascin_like; Immunoglobulin (Ig)-like domain of human neurofascin (NF)
    cd00063
    Location:794884
    FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
    pfam07679
    Location:694775
    I-set; Immunoglobulin I-set domain
    pfam00041
    Location:12081280
    fn3; Fibronectin type III domain
    pfam13882
    Location:13261410
    Bravo_FIGEY; Bravo-like intracellular region
    cd00096
    Location:615681
    Ig; Immunoglobulin domain
    cd05731
    Location:430500
    Ig3_L1-CAM_like; Third immunoglobulin (Ig)-like domain of the L1 cell adhesion molecule (CAM)
    cl11960
    Location:289381
    Ig; Immunoglobulin domain
  18. XM_024454288.1XP_024310056.1  neurofascin isoform X5

    Conserved Domains (8) summary
    cd05875
    Location:208284
    Ig_hNeurofascin_like; Immunoglobulin (Ig)-like domain of human neurofascin (NF)
    cd00063
    Location:777867
    FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
    pfam07679
    Location:677758
    I-set; Immunoglobulin I-set domain
    pfam00041
    Location:12701342
    fn3; Fibronectin type III domain
    pfam13882
    Location:13881472
    Bravo_FIGEY; Bravo-like intracellular region
    cd00096
    Location:598664
    Ig; Immunoglobulin domain
    cd05731
    Location:413483
    Ig3_L1-CAM_like; Third immunoglobulin (Ig)-like domain of the L1 cell adhesion molecule (CAM)
    cl11960
    Location:289381
    Ig; Immunoglobulin domain
  19. XM_024454299.1XP_024310067.1  neurofascin isoform X21

    Conserved Domains (7) summary
    cd05875
    Location:208284
    Ig_hNeurofascin_like; Immunoglobulin (Ig)-like domain of human neurofascin (NF)
    cd00063
    Location:779869
    FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
    pfam07679
    Location:694775
    I-set; Immunoglobulin I-set domain
    pfam13882
    Location:12211305
    Bravo_FIGEY; Bravo-like intracellular region
    cd00096
    Location:615681
    Ig; Immunoglobulin domain
    cd05731
    Location:430500
    Ig3_L1-CAM_like; Third immunoglobulin (Ig)-like domain of the L1 cell adhesion molecule (CAM)
    cl11960
    Location:289381
    Ig; Immunoglobulin domain
  20. XM_024454297.1XP_024310065.1  neurofascin isoform X18

    Conserved Domains (7) summary
    cd05875
    Location:208284
    Ig_hNeurofascin_like; Immunoglobulin (Ig)-like domain of human neurofascin (NF)
    cd00063
    Location:794884
    FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
    pfam07679
    Location:694775
    I-set; Immunoglobulin I-set domain
    pfam13882
    Location:12361320
    Bravo_FIGEY; Bravo-like intracellular region
    cd00096
    Location:615681
    Ig; Immunoglobulin domain
    cd05731
    Location:430500
    Ig3_L1-CAM_like; Third immunoglobulin (Ig)-like domain of the L1 cell adhesion molecule (CAM)
    cl11960
    Location:289381
    Ig; Immunoglobulin domain
  21. XM_011509325.2XP_011507627.2  neurofascin isoform X19

    Conserved Domains (7) summary
    cd05875
    Location:208284
    Ig_hNeurofascin_like; Immunoglobulin (Ig)-like domain of human neurofascin (NF)
    cd00063
    Location:794884
    FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
    pfam07679
    Location:694775
    I-set; Immunoglobulin I-set domain
    pfam13882
    Location:12311315
    Bravo_FIGEY; Bravo-like intracellular region
    cd00096
    Location:615681
    Ig; Immunoglobulin domain
    cd05731
    Location:430500
    Ig3_L1-CAM_like; Third immunoglobulin (Ig)-like domain of the L1 cell adhesion molecule (CAM)
    cl11960
    Location:289381
    Ig; Immunoglobulin domain
  22. XM_011509323.2XP_011507625.2  neurofascin isoform X16

    Conserved Domains (8) summary
    cd05875
    Location:208284
    Ig_hNeurofascin_like; Immunoglobulin (Ig)-like domain of human neurofascin (NF)
    cd00063
    Location:794884
    FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
    pfam07679
    Location:694775
    I-set; Immunoglobulin I-set domain
    pfam00041
    Location:11801252
    fn3; Fibronectin type III domain
    pfam13882
    Location:12981382
    Bravo_FIGEY; Bravo-like intracellular region
    cd00096
    Location:615681
    Ig; Immunoglobulin domain
    cd05731
    Location:430500
    Ig3_L1-CAM_like; Third immunoglobulin (Ig)-like domain of the L1 cell adhesion molecule (CAM)
    cl11960
    Location:289381
    Ig; Immunoglobulin domain
  23. XM_024454296.1XP_024310064.1  neurofascin isoform X17

    Conserved Domains (8) summary
    cd05875
    Location:208284
    Ig_hNeurofascin_like; Immunoglobulin (Ig)-like domain of human neurofascin (NF)
    cd00063
    Location:777867
    FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
    pfam07679
    Location:677758
    I-set; Immunoglobulin I-set domain
    pfam00041
    Location:11631235
    fn3; Fibronectin type III domain
    pfam13882
    Location:12811365
    Bravo_FIGEY; Bravo-like intracellular region
    cd00096
    Location:598664
    Ig; Immunoglobulin domain
    cd05731
    Location:413483
    Ig3_L1-CAM_like; Third immunoglobulin (Ig)-like domain of the L1 cell adhesion molecule (CAM)
    cl11960
    Location:289381
    Ig; Immunoglobulin domain
  24. XM_011509326.2XP_011507628.2  neurofascin isoform X28

    Conserved Domains (7) summary
    cd05875
    Location:208284
    Ig_hNeurofascin_like; Immunoglobulin (Ig)-like domain of human neurofascin (NF)
    cd00063
    Location:794884
    FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
    pfam07679
    Location:694775
    I-set; Immunoglobulin I-set domain
    pfam13882
    Location:11291213
    Bravo_FIGEY; Bravo-like intracellular region
    cd00096
    Location:615681
    Ig; Immunoglobulin domain
    cd05731
    Location:430500
    Ig3_L1-CAM_like; Third immunoglobulin (Ig)-like domain of the L1 cell adhesion molecule (CAM)
    cl11960
    Location:289381
    Ig; Immunoglobulin domain
  25. XM_011509327.2XP_011507629.2  neurofascin isoform X29

    Conserved Domains (7) summary
    cd05875
    Location:208284
    Ig_hNeurofascin_like; Immunoglobulin (Ig)-like domain of human neurofascin (NF)
    cd00063
    Location:794884
    FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
    pfam07679
    Location:694775
    I-set; Immunoglobulin I-set domain
    pfam13882
    Location:11241208
    Bravo_FIGEY; Bravo-like intracellular region
    cd00096
    Location:615681
    Ig; Immunoglobulin domain
    cd05731
    Location:430500
    Ig3_L1-CAM_like; Third immunoglobulin (Ig)-like domain of the L1 cell adhesion molecule (CAM)
    cl11960
    Location:289381
    Ig; Immunoglobulin domain
  26. XM_011509328.2XP_011507630.2  neurofascin isoform X36

    Related
    ENSP00000356141.3, ENST00000367173.7
    Conserved Domains (7) summary
    cd05875
    Location:208284
    Ig_hNeurofascin_like; Immunoglobulin (Ig)-like domain of human neurofascin (NF)
    cd00063
    Location:777867
    FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
    pfam07679
    Location:677758
    I-set; Immunoglobulin I-set domain
    pfam13882
    Location:11121196
    Bravo_FIGEY; Bravo-like intracellular region
    cd00096
    Location:598664
    Ig; Immunoglobulin domain
    cd05731
    Location:413483
    Ig3_L1-CAM_like; Third immunoglobulin (Ig)-like domain of the L1 cell adhesion molecule (CAM)
    cl11960
    Location:289381
    Ig; Immunoglobulin domain
  27. XM_011509312.1XP_011507614.1  neurofascin isoform X3

    Conserved Domains (9) summary
    cd05731
    Location:352422
    Ig3_L1-CAM_like; Third immunoglobulin (Ig)-like domain of the L1 cell adhesion molecule (CAM)
    cd05875
    Location:130206
    Ig6_hNeurofascin_like; Sixth immunoglobulin (Ig)-like domain of human neurofascin (NF)
    smart00408
    Location:537596
    IGc2; Immunoglobulin C-2 Type
    smart00410
    Location:342421
    IG_like; Immunoglobulin like
    cd00063
    Location:716806
    FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
    pfam07679
    Location:616697
    I-set; Immunoglobulin I-set domain
    pfam00041
    Location:12101281
    fn3; Fibronectin type III domain
    pfam13882
    Location:13271411
    Bravo_FIGEY; Bravo-like intracellular region
    cl11960
    Location:211303
    Ig; Immunoglobulin domain
  28. XM_005244989.3XP_005245046.2  neurofascin isoform X20

    Conserved Domains (8) summary
    cd05731
    Location:352422
    Ig3_L1-CAM_like; Third immunoglobulin (Ig)-like domain of the L1 cell adhesion molecule (CAM)
    cd05875
    Location:130206
    Ig6_hNeurofascin_like; Sixth immunoglobulin (Ig)-like domain of human neurofascin (NF)
    smart00408
    Location:537596
    IGc2; Immunoglobulin C-2 Type
    smart00410
    Location:342421
    IG_like; Immunoglobulin like
    cd00063
    Location:716806
    FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
    pfam07679
    Location:616697
    I-set; Immunoglobulin I-set domain
    pfam13882
    Location:11581242
    Bravo_FIGEY; Bravo-like intracellular region
    cl11960
    Location:211303
    Ig; Immunoglobulin domain
  29. XM_017000733.1XP_016856222.1  neurofascin isoform X6

  30. XM_005244991.3XP_005245048.2  neurofascin isoform X22

    Conserved Domains (8) summary
    cd05731
    Location:352422
    Ig3_L1-CAM_like; Third immunoglobulin (Ig)-like domain of the L1 cell adhesion molecule (CAM)
    cd05875
    Location:130206
    Ig6_hNeurofascin_like; Sixth immunoglobulin (Ig)-like domain of human neurofascin (NF)
    smart00408
    Location:537596
    IGc2; Immunoglobulin C-2 Type
    smart00410
    Location:342421
    IG_like; Immunoglobulin like
    cd00063
    Location:701791
    FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
    pfam07679
    Location:616697
    I-set; Immunoglobulin I-set domain
    pfam13882
    Location:11431227
    Bravo_FIGEY; Bravo-like intracellular region
    cl11960
    Location:211303
    Ig; Immunoglobulin domain
  31. XM_011509314.1XP_011507616.1  neurofascin isoform X7

    Conserved Domains (9) summary
    cd05731
    Location:335405
    Ig3_L1-CAM_like; Third immunoglobulin (Ig)-like domain of the L1 cell adhesion molecule (CAM)
    cd05875
    Location:130206
    Ig6_hNeurofascin_like; Sixth immunoglobulin (Ig)-like domain of human neurofascin (NF)
    smart00408
    Location:520579
    IGc2; Immunoglobulin C-2 Type
    smart00410
    Location:325404
    IG_like; Immunoglobulin like
    cd00063
    Location:699789
    FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
    pfam07679
    Location:599680
    I-set; Immunoglobulin I-set domain
    pfam00041
    Location:11931264
    fn3; Fibronectin type III domain
    pfam13882
    Location:13101394
    Bravo_FIGEY; Bravo-like intracellular region
    cl11960
    Location:211303
    Ig; Immunoglobulin domain
  32. XM_017000734.1XP_016856223.1  neurofascin isoform X9

  33. XM_005244993.3XP_005245050.2  neurofascin isoform X24

    Related
    ENSP00000385676.1, ENST00000404076.5
    Conserved Domains (8) summary
    cd05731
    Location:335405
    Ig3_L1-CAM_like; Third immunoglobulin (Ig)-like domain of the L1 cell adhesion molecule (CAM)
    cd05875
    Location:130206
    Ig6_hNeurofascin_like; Sixth immunoglobulin (Ig)-like domain of human neurofascin (NF)
    smart00408
    Location:520579
    IGc2; Immunoglobulin C-2 Type
    smart00410
    Location:325404
    IG_like; Immunoglobulin like
    cd00063
    Location:684774
    FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
    pfam07679
    Location:599680
    I-set; Immunoglobulin I-set domain
    pfam13882
    Location:11261210
    Bravo_FIGEY; Bravo-like intracellular region
    cl11960
    Location:211303
    Ig; Immunoglobulin domain
  34. XM_005244992.4XP_005245049.2  neurofascin isoform X23

    Conserved Domains (8) summary
    cd05731
    Location:352422
    Ig3_L1-CAM_like; Third immunoglobulin (Ig)-like domain of the L1 cell adhesion molecule (CAM)
    cd05875
    Location:130206
    Ig6_hNeurofascin_like; Sixth immunoglobulin (Ig)-like domain of human neurofascin (NF)
    smart00408
    Location:537596
    IGc2; Immunoglobulin C-2 Type
    smart00410
    Location:342421
    IG_like; Immunoglobulin like
    cd00063
    Location:701791
    FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
    pfam07679
    Location:616697
    I-set; Immunoglobulin I-set domain
    pfam13882
    Location:11381222
    Bravo_FIGEY; Bravo-like intracellular region
    cl11960
    Location:211303
    Ig; Immunoglobulin domain
  35. XM_005244997.3XP_005245054.2  neurofascin isoform X34

    See identical proteins and their annotated locations for XP_005245054.2

    Conserved Domains (6) summary
    cd05731
    Location:335405
    Ig3_L1-CAM_like; Third immunoglobulin (Ig)-like domain of the L1 cell adhesion molecule (CAM)
    cd05875
    Location:130206
    Ig6_hNeurofascin_like; Sixth immunoglobulin (Ig)-like domain of human neurofascin (NF)
    smart00408
    Location:520579
    IGc2; Immunoglobulin C-2 Type
    smart00410
    Location:325404
    IG_like; Immunoglobulin like
    pfam07679
    Location:599680
    I-set; Immunoglobulin I-set domain
    cl11960
    Location:211303
    Ig; Immunoglobulin domain
  36. XM_017000742.2XP_016856231.1  neurofascin isoform X33

  37. XM_017000741.1XP_016856230.1  neurofascin isoform X32

Suppressed Reference Sequence(s)

The following Reference Sequences have been suppressed. Explain

  1. NM_001005387.1: Suppressed sequence

    Description
    NM_001005387.1: This RefSeq was permanently suppressed because it is a nonsense-mediated mRNA decay (NMD) candidate.
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