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DDN dendrin [ Homo sapiens (human) ]

Gene ID: 23109, updated on 5-Aug-2018

Summary

Official Symbol
DDNprovided by HGNC
Official Full Name
dendrinprovided by HGNC
Primary source
HGNC:HGNC:24458
See related
Ensembl:ENSG00000181418 MIM:610588; Vega:OTTHUMG00000156183
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Expression
Biased expression in brain (RPKM 36.7) and kidney (RPKM 8.9) See more
Orthologs

Genomic context

See DDN in Genome Data Viewer
Location:
12q13.12
Exon count:
3
Annotation release Status Assembly Chr Location
109 current GRCh38.p12 (GCF_000001405.38) 12 NC_000012.12 (48995149..49001773, complement)
105 previous assembly GRCh37.p13 (GCF_000001405.25) 12 NC_000012.11 (49388933..49393088, complement)

Chromosome 12 - NC_000012.12Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC105369757 Neighboring gene Wnt family member 1 Neighboring gene uncharacterized LOC105369756 Neighboring gene DDN and PRKAG1 antisense RNA 1 Neighboring gene protein kinase AMP-activated non-catalytic subunit gamma 1 Neighboring gene lysine methyltransferase 2D

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Jun 15 11:32:44 2016

Bibliography

GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Clone Names

  • KIAA0749

Gene Ontology Provided by GOA

Function Evidence Code Pubs
RNA polymerase II proximal promoter sequence-specific DNA binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
transcription factor activity, RNA polymerase II proximal promoter sequence-specific DNA binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Process Evidence Code Pubs
positive regulation of transcription by RNA polymerase II IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Component Evidence Code Pubs
cell projection IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
cell projection IDA
Inferred from Direct Assay
more info
PubMed 
cytoplasm IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
cytoplasm IDA
Inferred from Direct Assay
more info
PubMed 
dendritic spine membrane IEA
Inferred from Electronic Annotation
more info
 
endoplasmic reticulum membrane IEA
Inferred from Electronic Annotation
more info
 
nucleus IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
perikaryon IEA
Inferred from Electronic Annotation
more info
 

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_015086.1NP_055901.2  dendrin

    See identical proteins and their annotated locations for NP_055901.2

    Status: VALIDATED

    Source sequence(s)
    AB018292, BC039264
    Consensus CDS
    CCDS31791.2
    UniProtKB/Swiss-Prot
    O94850
    Related
    ENSP00000390590.2, OTTHUMP00000209341, ENST00000421952.2, OTTHUMT00000343335
    Conserved Domains (1) summary
    pfam15498
    Location:55709
    Dendrin; Nephrin and CD2AP-binding protein, Dendrin

RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 109 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p12 Primary Assembly

Genomic

  1. NC_000012.12 Reference GRCh38.p12 Primary Assembly

    Range
    48995149..49001773 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_011538055.3XP_011536357.1  dendrin isoform X1

    See identical proteins and their annotated locations for XP_011536357.1

    Conserved Domains (1) summary
    pfam15498
    Location:1655
    Dendrin; Nephrin and CD2AP-binding protein, Dendrin
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