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Yrdc yrdC domain containing (E.coli) [ Mus musculus (house mouse) ]

Gene ID: 230734, updated on 5-Mar-2024

Summary

Official Symbol
Yrdcprovided by MGI
Official Full Name
yrdC domain containing (E.coli)provided by MGI
Primary source
MGI:MGI:2387201
See related
Ensembl:ENSMUSG00000028889 AllianceGenome:MGI:2387201
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
IRIP; ITIP
Summary
Predicted to enable nucleotidyltransferase activity and tRNA binding activity. Predicted to be involved in regulation of translational fidelity. Predicted to act upstream of or within negative regulation of transport. Located in membrane. Orthologous to human YRDC (yrdC N6-threonylcarbamoyltransferase domain containing). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Ubiquitous expression in adrenal adult (RPKM 33.7), ovary adult (RPKM 30.6) and 28 other tissues See more
Orthologs
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Genomic context

See Yrdc in Genome Data Viewer
Location:
4 D2.2; 4 57.92 cM
Exon count:
5
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 4 NC_000070.7 (124744552..124749035)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 4 NC_000070.6 (124850759..124855242)

Chromosome 4 - NC_000070.7Genomic Context describing neighboring genes Neighboring gene metal response element binding transcription factor 1 Neighboring gene RIKEN cDNA 1110065P20 gene Neighboring gene predicted gene, 54256 Neighboring gene mannosidase, endo-alpha-like Neighboring gene RIKEN cDNA 1700125G02 gene Neighboring gene Eph receptor A10 Neighboring gene cell division cycle associated 8 Neighboring gene STARR-positive B cell enhancer ABC_E424

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Endonuclease-mediated (1) 

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Clone Names

  • MGC38336

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables L-threonylcarbamoyladenylate synthase ISO
Inferred from Sequence Orthology
more info
 
enables double-stranded RNA binding IEA
Inferred from Electronic Annotation
more info
 
enables nucleotidyltransferase activity IBA
Inferred from Biological aspect of Ancestor
more info
 
enables protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
enables tRNA binding IBA
Inferred from Biological aspect of Ancestor
more info
 
enables transferase activity IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
acts_upstream_of_or_within negative regulation of transport ISO
Inferred from Sequence Orthology
more info
PubMed 
involved_in regulation of translational fidelity IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in tRNA threonylcarbamoyladenosine modification ISO
Inferred from Sequence Orthology
more info
 
Component Evidence Code Pubs
is_active_in cytoplasm IBA
Inferred from Biological aspect of Ancestor
more info
 
is_active_in cytoplasm ISO
Inferred from Sequence Orthology
more info
 
located_in membrane IDA
Inferred from Direct Assay
more info
PubMed 
is_active_in mitochondrion ISO
Inferred from Sequence Orthology
more info
 
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
threonylcarbamoyl-AMP synthase
Names
Ischemia/reperfusion-inducible protein
mIRIP
yrdC domain-containing protein, mitochondrial
NP_705794.2

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_153566.2NP_705794.2  threonylcarbamoyl-AMP synthase precursor

    See identical proteins and their annotated locations for NP_705794.2

    Status: VALIDATED

    Source sequence(s)
    AI413772, AK153627
    Consensus CDS
    CCDS18628.2
    UniProtKB/Swiss-Prot
    B1ARW9, B1ARX2, Q3U5F4, Q7TSY0, Q8CII1
    Related
    ENSMUSP00000099688.5, ENSMUST00000102628.11
    Conserved Domains (1) summary
    COG0009
    Location:70257
    SUA5; tRNA A37 threonylcarbamoyladenosine synthetase subunit TsaC/SUA5/YrdC [Translation, ribosomal structure and biogenesis]

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000070.7 Reference GRCm39 C57BL/6J

    Range
    124744552..124749035
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)