U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Zyg11a zyg-11 family member A, cell cycle regulator [ Mus musculus (house mouse) ]

Gene ID: 230590, updated on 5-Mar-2024

Summary

Official Symbol
Zyg11aprovided by MGI
Official Full Name
zyg-11 family member A, cell cycle regulatorprovided by MGI
Primary source
MGI:MGI:2446208
See related
Ensembl:ENSMUSG00000034645 AllianceGenome:MGI:2446208
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Summary
Predicted to be part of Cul2-RING ubiquitin ligase complex. Orthologous to human ZYG11A (zyg-11 family member A, cell cycle regulator). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Biased expression in liver adult (RPKM 1.6), mammary gland adult (RPKM 1.2) and 12 other tissues See more
Orthologs
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

See Zyg11a in Genome Data Viewer
Location:
4 C7; 4 50.31 cM
Exon count:
15
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 4 NC_000070.7 (108037442..108075285, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 4 NC_000070.6 (108180245..108218088, complement)

Chromosome 4 - NC_000070.7Genomic Context describing neighboring genes Neighboring gene predicted gene, 54248 Neighboring gene STARR-seq mESC enhancer starr_11032 Neighboring gene enoyl Coenzyme A hydratase domain containing 2 Neighboring gene STARR-seq mESC enhancer starr_11034 Neighboring gene predicted gene, 54249 Neighboring gene zyg-ll family member B, cell cycle regulator Neighboring gene STARR-positive B cell enhancer ABC_E2701 Neighboring gene STARR-seq mESC enhancer starr_11037 Neighboring gene STARR-seq mESC enhancer starr_11038 Neighboring gene STARR-positive B cell enhancer ABC_E11249 Neighboring gene STARR-positive B cell enhancer ABC_E10246 Neighboring gene STARR-positive B cell enhancer ABC_E7979 Neighboring gene CapStarr-seq enhancer MGSCv37_chr4:108000774-108000883 Neighboring gene STARR-positive B cell enhancer ABC_E2702 Neighboring gene cytochrome c oxidase assembly factor 7

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

General protein information

Preferred Names
protein zyg-11 homolog A
Names
zyg-11 homolog A

NCBI Reference Sequences (RefSeq)

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001167936.3NP_001161408.2  protein zyg-11 homolog A

    Status: VALIDATED

    Source sequence(s)
    BX293563
    Consensus CDS
    CCDS51256.2
    UniProtKB/TrEMBL
    A0A217FL76, F8WHU3
    Related
    ENSMUSP00000102301.3, ENSMUST00000106690.9

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000070.7 Reference GRCm39 C57BL/6J

    Range
    108037442..108075285 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006502976.4XP_006503039.1  protein zyg-11 homolog A isoform X1

    UniProtKB/TrEMBL
    A0A1Y7VNL1, F8WHU3
    Related
    ENSMUSP00000152477.2, ENSMUST00000223127.2
    Conserved Domains (2) summary
    COG4886
    Location:156294
    LRR; Leucine-rich repeat (LRR) protein [Transcription]
    sd00034
    Location:158182
    LRR_AMN1; leucine-rich repeat [structural motif]
  2. XM_017320136.1XP_017175625.1  protein zyg-11 homolog A isoform X2

    UniProtKB/Swiss-Prot
    A2BFL2, Q8VC01
    Conserved Domains (2) summary
    COG4886
    Location:56194
    LRR; Leucine-rich repeat (LRR) protein [Transcription]
    sd00034
    Location:5882
    LRR_AMN1; leucine-rich repeat [structural motif]