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Coq3 coenzyme Q3 methyltransferase [ Mus musculus (house mouse) ]

Gene ID: 230027, updated on 31-Jan-2019

Summary

Official Symbol
Coq3provided by MGI
Official Full Name
coenzyme Q3 methyltransferaseprovided by MGI
Primary source
MGI:MGI:101813
See related
Ensembl:ENSMUSG00000028247
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
C77934; 4732433J24
Expression
Ubiquitous expression in heart adult (RPKM 5.7), placenta adult (RPKM 4.2) and 28 other tissues See more
Orthologs

Genomic context

See Coq3 in Genome Data Viewer
Location:
4 A3; 4 9.11 cM
Exon count:
8
Annotation release Status Assembly Chr Location
106 current GRCm38.p4 (GCF_000001635.24) 4 NC_000070.6 (21879675..21912163)
Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 4 NC_000070.5 (21806822..21839273)

Chromosome 4 - NC_000070.6Genomic Context describing neighboring genes Neighboring gene thiosulfate sulfurtransferase (rhodanese)-like domain containing 3 Neighboring gene ubiquitin specific petidase 45 Neighboring gene RIKEN cDNA 4930528A17 gene Neighboring gene PNN interacting serine/arginine-rich Neighboring gene failed axon connections homolog Neighboring gene WEE1 homolog 2 pseudogene

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Gene trapped (1) 
  • Endonuclease-mediated (1) 

Pathways from BioSystems

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
2-polyprenyl-6-methoxy-1,4-benzoquinone methyltransferase activity IEA
Inferred from Electronic Annotation
more info
 
3-demethylubiquinone-9 3-O-methyltransferase activity IEA
Inferred from Electronic Annotation
more info
 
O-methyltransferase activity ISO
Inferred from Sequence Orthology
more info
 
hexaprenyldihydroxybenzoate methyltransferase activity ISO
Inferred from Sequence Orthology
more info
 
methyltransferase activity IEA
Inferred from Electronic Annotation
more info
 
transferase activity IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
glycerol metabolic process ISO
Inferred from Sequence Orthology
more info
 
methylation ISO
Inferred from Sequence Orthology
more info
 
regulation of ubiquinone biosynthetic process ISO
Inferred from Sequence Orthology
more info
 
ubiquinone biosynthetic process ISO
Inferred from Sequence Orthology
more info
 
Component Evidence Code Pubs
membrane IEA
Inferred from Electronic Annotation
more info
 
mitochondrial inner membrane IEA
Inferred from Electronic Annotation
more info
 
mitochondrion HDA PubMed 
mitochondrion ISO
Inferred from Sequence Orthology
more info
 

General protein information

Preferred Names
ubiquinone biosynthesis O-methyltransferase, mitochondrial
Names
2-polyprenyl-6-hydroxyphenol methylase
2-polyprenyl-6-hydroxyphenyl methylase
3,4-dihydroxy-5-hexaprenylbenzoate methyltransferase
3-demethylubiquinol 3-O-methyltransferase
3-demethylubiquinone-9 3-methyltransferase
Coenzyme Q (ubiquinone)
DHHB methyltransferase
DHHB-MT
DHHB-MTase
coenzyme Q3 homolog, methyltransferase
dihydroxyhexaprenylbenzoate methyltransferase
hexaprenyldihydroxybenzoate methyltransferase, mitochondrial
polyprenyldihydroxybenzoate methyltransferase
NP_766275.1
XP_006537871.1

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001356348.1NP_001343277.1  ubiquinone biosynthesis O-methyltransferase, mitochondrial isoform 2

    Status: VALIDATED

    Source sequence(s)
    AK028680, AK035318, AL772187
    Conserved Domains (1) summary
    TIGR01983
    Location:38268
    UbiG; ubiquinone biosynthesis O-methyltransferase
  2. NM_172687.2NP_766275.1  ubiquinone biosynthesis O-methyltransferase, mitochondrial isoform 1

    See identical proteins and their annotated locations for NP_766275.1

    Status: VALIDATED

    Source sequence(s)
    AK028680, AL772187, CJ077260
    Consensus CDS
    CCDS18003.1
    UniProtKB/Swiss-Prot
    Q8BMS4
    Related
    ENSMUSP00000029909.2, ENSMUST00000029909.2
    Conserved Domains (2) summary
    TIGR01983
    Location:97327
    UbiG; ubiquinone biosynthesis O-methyltransferase
    pfam08241
    Location:152251
    Methyltransf_11; Methyltransferase domain

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 106

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm38.p4 C57BL/6J

Genomic

  1. NC_000070.6 Reference GRCm38.p4 C57BL/6J

    Range
    21879675..21912163
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006537808.2XP_006537871.1  ubiquinone biosynthesis O-methyltransferase, mitochondrial isoform X1

    UniProtKB/Swiss-Prot
    Q8BMS4
    Conserved Domains (1) summary
    TIGR01983
    Location:38268
    UbiG; ubiquinone biosynthesis O-methyltransferase
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