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Ciart circadian associated repressor of transcription [ Mus musculus (house mouse) ]

Gene ID: 229599, updated on 5-Mar-2024

Summary

Official Symbol
Ciartprovided by MGI
Official Full Name
circadian associated repressor of transcriptionprovided by MGI
Primary source
MGI:MGI:2684975
See related
Ensembl:ENSMUSG00000038550 AllianceGenome:MGI:2684975
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Gm129; Chrono
Summary
Enables E-box binding activity. Involved in circadian regulation of gene expression; locomotor rhythm; and negative regulation of transcription, DNA-templated. Located in nucleus. Orthologous to human CIART (circadian associated repressor of transcription). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Broad expression in bladder adult (RPKM 9.0), cortex adult (RPKM 8.4) and 20 other tissues See more
Orthologs
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Genomic context

See Ciart in Genome Data Viewer
Location:
3 F2.1; 3 41.42 cM
Exon count:
9
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 3 NC_000069.7 (95785812..95790012, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 3 NC_000069.6 (95878500..95882257, complement)

Chromosome 3 - NC_000069.7Genomic Context describing neighboring genes Neighboring gene pre-mRNA processing factor 3 Neighboring gene STARR-positive B cell enhancer ABC_E10199 Neighboring gene RIKEN cDNA C920021L13 gene Neighboring gene mitochondrial ribosomal protein S21 Neighboring gene STARR-positive B cell enhancer ABC_E9562 Neighboring gene cDNA sequence BC028528 Neighboring gene STARR-positive B cell enhancer ABC_E2673 Neighboring gene aph1 homolog A, gamma secretase subunit Neighboring gene carbonic anhydrase 14 Neighboring gene CapStarr-seq enhancer MGSCv37_chr3:95732686-95732932 Neighboring gene predicted gene, 46815

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Gene trapped (1) 
  • Targeted (2) 
  • Endonuclease-mediated (5) 

General gene information

Markers

Gene Ontology Provided by MGI

Process Evidence Code Pubs
involved_in circadian regulation of gene expression IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in circadian regulation of gene expression IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in locomotor rhythm IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in negative regulation of DNA-templated transcription IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in negative regulation of DNA-templated transcription IDA
Inferred from Direct Assay
more info
PubMed 
acts_upstream_of_or_within rhythmic process IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
 
located_in nucleus IDA
Inferred from Direct Assay
more info
PubMed 

General protein information

Preferred Names
circadian-associated transcriptional repressor
Names
chIP-derived repressor of network oscillator
computationally highlighted repressor of the network oscillator

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001033302.3NP_001028474.1  circadian-associated transcriptional repressor isoform 1

    See identical proteins and their annotated locations for NP_001028474.1

    Status: VALIDATED

    Source sequence(s)
    AC092855
    Consensus CDS
    CCDS50997.1
    UniProtKB/Swiss-Prot
    Q3TQ03, Q3U1B8
    UniProtKB/TrEMBL
    A2RTE4
    Related
    ENSMUSP00000049308.4, ENSMUST00000036418.10
    Conserved Domains (1) summary
    pfam15673
    Location:85360
    Ciart; Circadian-associated transcriptional repressor
  2. NM_001411319.1NP_001398248.1  circadian-associated transcriptional repressor isoform 1

    Status: VALIDATED

    Source sequence(s)
    AC092855
    UniProtKB/Swiss-Prot
    Q3TQ03, Q3U1B8
    UniProtKB/TrEMBL
    A2RTE4
  3. NM_001411320.1NP_001398249.1  circadian-associated transcriptional repressor isoform 1

    Status: VALIDATED

    Source sequence(s)
    AC092855
    UniProtKB/Swiss-Prot
    Q3TQ03, Q3U1B8
    UniProtKB/TrEMBL
    A2RTE4
  4. NM_001411321.1NP_001398250.1  circadian-associated transcriptional repressor isoform 1

    Status: VALIDATED

    Source sequence(s)
    AC092855
    UniProtKB/Swiss-Prot
    Q3TQ03, Q3U1B8
    UniProtKB/TrEMBL
    A2RTE4
  5. NM_001411322.1NP_001398251.1  circadian-associated transcriptional repressor isoform 1

    Status: VALIDATED

    Source sequence(s)
    AC092855
    UniProtKB/Swiss-Prot
    Q3TQ03, Q3U1B8
    UniProtKB/TrEMBL
    A2RTE4
  6. NM_001411323.1NP_001398252.1  circadian-associated transcriptional repressor isoform 1

    Status: VALIDATED

    Source sequence(s)
    AC092855
    UniProtKB/Swiss-Prot
    Q3TQ03, Q3U1B8
    UniProtKB/TrEMBL
    A2RTE4
    Related
    ENSMUSP00000124943.2, ENSMUST00000159739.8
  7. NM_001411324.1NP_001398253.1  circadian-associated transcriptional repressor isoform 2

    Status: VALIDATED

    Source sequence(s)
    AC092855
  8. NM_001411325.1NP_001398254.1  circadian-associated transcriptional repressor isoform 2

    Status: VALIDATED

    Source sequence(s)
    AC092855
  9. NM_001411326.1NP_001398255.1  circadian-associated transcriptional repressor isoform 2

    Status: VALIDATED

    Source sequence(s)
    AC092855
  10. NM_001411327.1NP_001398256.1  circadian-associated transcriptional repressor isoform 2

    Status: VALIDATED

    Source sequence(s)
    AC092855
  11. NM_001411328.1NP_001398257.1  circadian-associated transcriptional repressor isoform 2

    Status: VALIDATED

    Source sequence(s)
    AC092855
  12. NM_001411329.1NP_001398258.1  circadian-associated transcriptional repressor isoform 3

    Status: VALIDATED

    Source sequence(s)
    AC092855
  13. NM_001411330.1NP_001398259.1  circadian-associated transcriptional repressor isoform 3

    Status: VALIDATED

    Source sequence(s)
    AC092855

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000069.7 Reference GRCm39 C57BL/6J

    Range
    95785812..95790012 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)