Format

Send to:

Choose Destination

Pbxip1 pre B cell leukemia transcription factor interacting protein 1 [ Mus musculus (house mouse) ]

Gene ID: 229534, updated on 25-Nov-2021

Summary

Official Symbol
Pbxip1provided by MGI
Official Full Name
pre B cell leukemia transcription factor interacting protein 1provided by MGI
Primary source
MGI:MGI:2441670
See related
Ensembl:ENSMUSG00000042613
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
4732463H20Rik
Expression
Ubiquitous expression in bladder adult (RPKM 58.7), colon adult (RPKM 38.5) and 25 other tissues See more
Orthologs
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

See Pbxip1 in Genome Data Viewer
Location:
3; 3 F1
Exon count:
11
Annotation release Status Assembly Chr Location
109 current GRCm39 (GCF_000001635.27) 3 NC_000069.7 (89343982..89358259)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 3 NC_000069.6 (89436675..89450952)
Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 3 NC_000069.5 (89240626..89254874)

Chromosome 3 - NC_000069.7Genomic Context describing neighboring genes Neighboring gene src homology 2 domain-containing transforming protein C1 Neighboring gene pygopus 2 Neighboring gene phosphomevalonate kinase Neighboring gene potassium intermediate/small conductance calcium-activated channel, subfamily N, member 3

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Clone Names

  • MGC38361

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables DNA-binding transcription factor binding ISO
Inferred from Sequence Orthology
more info
 
enables protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
enables transcription coactivator activity IDA
Inferred from Direct Assay
more info
PubMed 
enables transcription coactivator activity IMP
Inferred from Mutant Phenotype
more info
PubMed 
enables transcription corepressor activity IEA
Inferred from Electronic Annotation
more info
 
enables transcription corepressor activity ISO
Inferred from Sequence Orthology
more info
 
Process Evidence Code Pubs
acts_upstream_of_or_within articular cartilage development IMP
Inferred from Mutant Phenotype
more info
PubMed 
acts_upstream_of_or_within cell adhesion IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in cell differentiation IEA
Inferred from Electronic Annotation
more info
 
acts_upstream_of_or_within cell migration IMP
Inferred from Mutant Phenotype
more info
PubMed 
acts_upstream_of_or_within extracellular matrix disassembly IMP
Inferred from Mutant Phenotype
more info
PubMed 
acts_upstream_of_or_within gene expression IMP
Inferred from Mutant Phenotype
more info
PubMed 
acts_upstream_of_or_within gene expression involved in extracellular matrix organization IMP
Inferred from Mutant Phenotype
more info
PubMed 
acts_upstream_of_or_within histone H3-K56 acetylation IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in negative regulation of transcription, DNA-templated IEA
Inferred from Electronic Annotation
more info
 
involved_in negative regulation of transcription, DNA-templated ISO
Inferred from Sequence Orthology
more info
 
acts_upstream_of_or_within positive regulation of Wnt signaling pathway IDA
Inferred from Direct Assay
more info
PubMed 
acts_upstream_of_or_within positive regulation of Wnt signaling pathway IMP
Inferred from Mutant Phenotype
more info
PubMed 
acts_upstream_of_or_within positive regulation of chondrocyte proliferation IMP
Inferred from Mutant Phenotype
more info
PubMed 
acts_upstream_of_or_within positive regulation of transcription, DNA-templated IDA
Inferred from Direct Assay
more info
PubMed 
acts_upstream_of_or_within positive regulation of transcription, DNA-templated IMP
Inferred from Mutant Phenotype
more info
PubMed 
acts_upstream_of_or_within production of molecular mediator involved in inflammatory response IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in regulation of Rho guanyl-nucleotide exchange factor activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Component Evidence Code Pubs
located_in chromatin IDA
Inferred from Direct Assay
more info
PubMed 
located_in cytoplasm IDA
Inferred from Direct Assay
more info
PubMed 
located_in cytoskeleton IEA
Inferred from Electronic Annotation
more info
 
located_in cytosol ISO
Inferred from Sequence Orthology
more info
 
is_active_in membrane IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
located_in microtubule IEA
Inferred from Electronic Annotation
more info
 
located_in nucleus IDA
Inferred from Direct Assay
more info
PubMed 
located_in nucleus ISO
Inferred from Sequence Orthology
more info
 
part_of transcription regulator complex IDA
Inferred from Direct Assay
more info
PubMed 

General protein information

Preferred Names
pre-B-cell leukemia transcription factor-interacting protein 1
Names
hematopoietic PBX-interacting protein

NCBI Reference Sequences (RefSeq)

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_146131.2NP_666243.1  pre-B-cell leukemia transcription factor-interacting protein 1

    See identical proteins and their annotated locations for NP_666243.1

    Status: VALIDATED

    Source sequence(s)
    AC171273, AK028858, AK047898, CD742482
    Consensus CDS
    CCDS17510.1
    UniProtKB/Swiss-Prot
    Q3TVI8
    Related
    ENSMUSP00000040429.4, ENSMUST00000038942.10
    Conserved Domains (1) summary
    TIGR04211
    Location:283403
    SH3_and_anchor; SH3 domain protein

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000069.7 Reference GRCm39 C57BL/6J

    Range
    89343982..89358259
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006501351.2XP_006501414.1  pre-B-cell leukemia transcription factor-interacting protein 1 isoform X1

    See identical proteins and their annotated locations for XP_006501414.1

    Conserved Domains (1) summary
    TIGR04211
    Location:290410
    SH3_and_anchor; SH3 domain protein
  2. XM_006501353.3XP_006501416.1  pre-B-cell leukemia transcription factor-interacting protein 1 isoform X2

    See identical proteins and their annotated locations for XP_006501416.1

    UniProtKB/Swiss-Prot
    Q3TVI8
    Conserved Domains (1) summary
    TIGR04211
    Location:283403
    SH3_and_anchor; SH3 domain protein
  3. XM_006501352.3XP_006501415.1  pre-B-cell leukemia transcription factor-interacting protein 1 isoform X1

    See identical proteins and their annotated locations for XP_006501415.1

    Conserved Domains (1) summary
    TIGR04211
    Location:290410
    SH3_and_anchor; SH3 domain protein
Support Center