Format

Send to:

Choose Destination

HABP4 hyaluronan binding protein 4 [ Homo sapiens (human) ]

Gene ID: 22927, updated on 4-May-2020

Summary

Official Symbol
HABP4provided by HGNC
Official Full Name
hyaluronan binding protein 4provided by HGNC
Primary source
HGNC:HGNC:17062
See related
Ensembl:ENSG00000130956 MIM:617369
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
IHABP4; IHABP-4; Ki-1/57; SERBP1L
Expression
Broad expression in brain (RPKM 24.4), testis (RPKM 16.9) and 22 other tissues See more
Orthologs

Genomic context

See HABP4 in Genome Data Viewer
Location:
9q22.32
Exon count:
9
Annotation release Status Assembly Chr Location
109.20200228 current GRCh38.p13 (GCF_000001405.39) 9 NC_000009.12 (96450162..96491336)
105 previous assembly GRCh37.p13 (GCF_000001405.25) 9 NC_000009.11 (99212414..99253618)

Chromosome 9 - NC_000009.12Genomic Context describing neighboring genes Neighboring gene hydroxysteroid 17-beta dehydrogenase 3 Neighboring gene solute carrier family 35 member D2 Neighboring gene zinc finger protein 367 Neighboring gene NSA2 pseudogene 7 Neighboring gene cell division cycle 14B Neighboring gene uncharacterized LOC105376163 Neighboring gene peroxiredoxin like 2C

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Clone Names

  • MGC825

Gene Ontology Provided by GOA

Function Evidence Code Pubs
RNA binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
RNA binding IEA
Inferred from Electronic Annotation
more info
 
SUMO binding IDA
Inferred from Direct Assay
more info
PubMed 
protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
Process Evidence Code Pubs
PML body organization IDA
Inferred from Direct Assay
more info
PubMed 
RNA splicing IEA
Inferred from Electronic Annotation
more info
 
cellular response to mechanical stimulus ISS
Inferred from Sequence or Structural Similarity
more info
 
mRNA processing IEA
Inferred from Electronic Annotation
more info
 
negative regulation of DNA binding IDA
Inferred from Direct Assay
more info
PubMed 
platelet degranulation TAS
Traceable Author Statement
more info
 
positive regulation of RNA splicing IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
positive regulation of RNA splicing IMP
Inferred from Mutant Phenotype
more info
PubMed 
positive regulation of translational initiation IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
positive regulation of translational initiation IMP
Inferred from Mutant Phenotype
more info
PubMed 
Component Evidence Code Pubs
Cajal body IDA
Inferred from Direct Assay
more info
PubMed 
Gemini of coiled bodies IDA
Inferred from Direct Assay
more info
PubMed 
Golgi apparatus IDA
Inferred from Direct Assay
more info
 
cytoplasm IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
cytoplasm IDA
Inferred from Direct Assay
more info
PubMed 
cytoplasm ISS
Inferred from Sequence or Structural Similarity
more info
 
cytoplasmic stress granule IDA
Inferred from Direct Assay
more info
PubMed 
cytosol IDA
Inferred from Direct Assay
more info
 
cytosol TAS
Traceable Author Statement
more info
 
extracellular region TAS
Traceable Author Statement
more info
 
nuclear speck IDA
Inferred from Direct Assay
more info
PubMed 
nucleolus IDA
Inferred from Direct Assay
more info
PubMed 
nucleoplasm IDA
Inferred from Direct Assay
more info
 
nucleus IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
nucleus IDA
Inferred from Direct Assay
more info
PubMed 
nucleus ISS
Inferred from Sequence or Structural Similarity
more info
 
sarcomere ISS
Inferred from Sequence or Structural Similarity
more info
 
sarcoplasm IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
intracellular hyaluronan-binding protein 4
Names
chromodomain helicase DNA binding protein 3 interacting protein
intracellular antigen detected by monoclonal antibody Ki-1
ki-1/57 intracellular antigen

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_014282.4NP_055097.2  intracellular hyaluronan-binding protein 4

    See identical proteins and their annotated locations for NP_055097.2

    Status: VALIDATED

    Source sequence(s)
    AF241831, AK025144, BC018788, CN287447, DR006985
    Consensus CDS
    CCDS6719.1
    UniProtKB/Swiss-Prot
    Q5JVS0
    Related
    ENSP00000364398.4, ENST00000375249.5
    Conserved Domains (2) summary
    pfam04774
    Location:212316
    HABP4_PAI-RBP1; Hyaluronan / mRNA binding family
    pfam16174
    Location:16131
    IHABP4_N; Intracellular hyaluronan-binding protein 4 N-terminal

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000009.12 Reference GRCh38.p13 Primary Assembly

    Range
    96450162..96491336
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_017014484.1XP_016869973.1  intracellular hyaluronan-binding protein 4 isoform X2

    Conserved Domains (1) summary
    pfam04774
    Location:74178
    HABP4_PAI-RBP1; Hyaluronan / mRNA binding family
  2. XM_005251812.3XP_005251869.1  intracellular hyaluronan-binding protein 4 isoform X1

    Conserved Domains (1) summary
    pfam04774
    Location:102206
    HABP4_PAI-RBP1; Hyaluronan / mRNA binding family

RNA

  1. XR_001746249.1 RNA Sequence

Support Center