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Zbtb10 zinc finger and BTB domain containing 10 [ Mus musculus (house mouse) ]

Gene ID: 229055, updated on 8-Feb-2024

Summary

Official Symbol
Zbtb10provided by MGI
Official Full Name
zinc finger and BTB domain containing 10provided by MGI
Primary source
MGI:MGI:2139883
See related
Ensembl:ENSMUSG00000069114 AllianceGenome:MGI:2139883
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
RINZF; 4832414A18
Summary
Predicted to enable RNA polymerase II transcription regulatory region sequence-specific DNA binding activity. Predicted to be involved in negative regulation of transcription by RNA polymerase II. Predicted to be located in nucleoplasm. Predicted to be active in nucleus. Orthologous to human ZBTB10 (zinc finger and BTB domain containing 10). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Broad expression in placenta adult (RPKM 9.7), CNS E11.5 (RPKM 3.6) and 18 other tissues See more
Orthologs
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Genomic context

See Zbtb10 in Genome Data Viewer
Location:
3 A1; 3 2.25 cM
Exon count:
6
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 3 NC_000069.7 (9315627..9350393)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 3 NC_000069.6 (9250567..9285333)

Chromosome 3 - NC_000069.7Genomic Context describing neighboring genes Neighboring gene predicted gene, 33018 Neighboring gene STARR-seq mESC enhancer starr_06898 Neighboring gene predicted gene, 52635 Neighboring gene STARR-seq mESC enhancer starr_06899 Neighboring gene STARR-positive B cell enhancer mm9_chr3:9249729-9250030 Neighboring gene STARR-seq mESC enhancer starr_06901 Neighboring gene predicted gene, 41997 Neighboring gene STARR-seq mESC enhancer starr_06902 Neighboring gene VISTA enhancer mm551 Neighboring gene RIKEN cDNA C030034L19 gene Neighboring gene STARR-seq mESC enhancer starr_06904 Neighboring gene zinc finger protein 704

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Endonuclease-mediated (3) 

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Gene Ontology Provided by MGI

Process Evidence Code Pubs
involved_in negative regulation of transcription by RNA polymerase II ISO
Inferred from Sequence Orthology
more info
 
involved_in regulation of transcription by RNA polymerase II IBA
Inferred from Biological aspect of Ancestor
more info
 
Component Evidence Code Pubs
located_in chromosome, telomeric region ISO
Inferred from Sequence Orthology
more info
 
located_in nucleoplasm ISO
Inferred from Sequence Orthology
more info
 
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
 

General protein information

Preferred Names
zinc finger and BTB domain-containing protein 10

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_177660.3NP_808328.2  zinc finger and BTB domain-containing protein 10

    Status: VALIDATED

    Source sequence(s)
    AC126450, AK048280, AK048365, AK083443, BM899487, BY718125, CB525445, CJ114435, CK341409
    Consensus CDS
    CCDS50861.1
    UniProtKB/TrEMBL
    E9Q8X5
    Related
    ENSMUSP00000119386.2, ENSMUST00000155203.2
    Conserved Domains (6) summary
    smart00225
    Location:358454
    BTB; Broad-Complex, Tramtrack and Bric a brac
    smart00597
    Location:242309
    ZnF_TTF; zinc finger in transposases and transcription factors
    sd00017
    Location:716736
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam00651
    Location:347453
    BTB; BTB/POZ domain
    pfam13465
    Location:729753
    zf-H2C2_2; Zinc-finger double domain
    pfam13909
    Location:714738
    zf-H2C2_5; C2H2-type zinc-finger domain

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000069.7 Reference GRCm39 C57BL/6J

    Range
    9315627..9350393
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)