U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Kat14 lysine acetyltransferase 14 [ Mus musculus (house mouse) ]

Gene ID: 228714, updated on 5-Mar-2024

Summary

Official Symbol
Kat14provided by MGI
Official Full Name
lysine acetyltransferase 14provided by MGI
Primary source
MGI:MGI:1917264
See related
Ensembl:ENSMUSG00000027425 AllianceGenome:MGI:1917264
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
ATAC2; Csrp2bp; D2Wsu131e; D2Ertd473e; E430020F17; 2510008M08Rik
Summary
Predicted to enable histone acetyltransferase activity. Acts upstream of or within G2/M transition of mitotic cell cycle and histone acetylation. Located in nucleus. Part of ATAC complex. Is expressed in embryo and extraembryonic component. Orthologous to human KAT14 (lysine acetyltransferase 14). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Ubiquitous expression in CNS E11.5 (RPKM 11.4), placenta adult (RPKM 8.8) and 28 other tissues See more
Orthologs
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

See Kat14 in Genome Data Viewer
Location:
2 G1; 2 71.01 cM
Exon count:
11
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 2 NC_000068.8 (144210952..144249595)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 2 NC_000068.7 (144369032..144407675)

Chromosome 2 - NC_000068.8Genomic Context describing neighboring genes Neighboring gene peptidylprolyl isomerase A pseudogene 2_1789.1 Neighboring gene STARR-seq mESC enhancer starr_05912 Neighboring gene calcium binding and coiled-coil domain 2 pseudogene Neighboring gene PET117 homolog Neighboring gene STARR-seq mESC enhancer starr_05913 Neighboring gene predicted gene, 46768 Neighboring gene zinc finger protein 133, pseudogene

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables acyltransferase activity, transferring groups other than amino-acyl groups IEA
Inferred from Electronic Annotation
more info
 
enables histone acetyltransferase activity IBA
Inferred from Biological aspect of Ancestor
more info
 
enables histone acetyltransferase activity ISO
Inferred from Sequence Orthology
more info
PubMed 
enables protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
Component Evidence Code Pubs
part_of ATAC complex IDA
Inferred from Direct Assay
more info
PubMed 
part_of ATAC complex ISO
Inferred from Sequence Orthology
more info
 
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 
located_in mitotic spindle NAS
Non-traceable Author Statement
more info
PubMed 
located_in nucleus IDA
Inferred from Direct Assay
more info
PubMed 
located_in nucleus ISO
Inferred from Sequence Orthology
more info
 

General protein information

Preferred Names
cysteine-rich protein 2-binding protein
Names
ADA2A-containing complex subunit 2
CRP2-binding partner
CRP2BP
CSRP2-binding protein
cysteine and glycine-rich protein 2 binding protein

NCBI Reference Sequences (RefSeq)

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001166640.1NP_001160112.1  cysteine-rich protein 2-binding protein isoform 2

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) lacks an internal segment in the 5' region, resulting in a downstream AUG start codon, as compared to variant 1. The resulting isoform (2) has a shorter N-terminus, as compared to isoform 1.
    Source sequence(s)
    AL808123
    UniProtKB/TrEMBL
    E9QA90
    Related
    ENSMUSP00000130785.2, ENSMUST00000147747.8
    Conserved Domains (2) summary
    COG0456
    Location:554632
    RimI; Ribosomal protein S18 acetylase RimI and related acetyltransferases [Translation, ribosomal structure and biogenesis]
    pfam00583
    Location:552621
    Acetyltransf_1; Acetyltransferase (GNAT) family
  2. NM_181417.3NP_852082.2  cysteine-rich protein 2-binding protein isoform 1

    See identical proteins and their annotated locations for NP_852082.2

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) encodes the longer isoform (1).
    Source sequence(s)
    AL808123
    Consensus CDS
    CCDS16819.1
    UniProtKB/Swiss-Prot
    A2ANA8, Q8CID0
    Related
    ENSMUSP00000028911.9, ENSMUST00000028911.15
    Conserved Domains (2) summary
    COG0456
    Location:648760
    RimI; Ribosomal protein S18 acetylase RimI and related acetyltransferases [Translation, ribosomal structure and biogenesis]
    pfam00583
    Location:680749
    Acetyltransf_1; Acetyltransferase (GNAT) family

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000068.8 Reference GRCm39 C57BL/6J

    Range
    144210952..144249595
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)